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Article: Time course of esophageal lesions after catheter ablation with cryothermal and radiofrequency ablation: Implication for atrio-esophageal fistula formation after catheter ablation for atrial fibrillation

TitleTime course of esophageal lesions after catheter ablation with cryothermal and radiofrequency ablation: Implication for atrio-esophageal fistula formation after catheter ablation for atrial fibrillation
Authors
Issue Date2007
PublisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1045-3873
Citation
Journal Of Cardiovascular Electrophysiology, 2007, v. 18 n. 6, p. 642-646 How to Cite?
AbstractBackground: Atrio-esophageal fistulas have been described as a consequence of radiofrequency (RF) ablation for the treatment of atrial fibrillation (AF). However, whether cryoablation can avoid this potential fatal complication remains unclear. Methods and Results: We studied the effects of direct application of RF and cryoablation on the cervical esophagus in 16 calves. Cryoablation was performed with a 6.5-mm catheter probe using a single 5-minute freeze at <-80°C, and RF ablation was delivered with an 8-mm catheter electrode at 50 W and 50°C for 45-60 seconds. Histopathologic assessments were performed at 1, 4, 7, and 14 day(s) after completion of the ablation protocol: four animals were examined each day. A total of 85 direct esophageal ablations were performed: 41 with RF and 44 with cryoablation. There were no significant differences in lesion width, depth, or volume between cryoablation and RF ablation at Day 1, 4, and 14 after the procedure (P > 0.05). However, lesion width and volume were significantly larger with RF than with cryoablation at Day 7. Although acute (Day 1) and chronic (Day 14) RF and cryoablation lesions were of comparable size, histologic evidence of partial- to full-wall esophageal lesion ulceration was observed in 0 of 44 (0%) lesions with cryoablation, compared with 9 of 41 (22%) lesions with RF ablation (P = 0.0025). Conclusions: Direct application of cryoablation and RF ablation created similar acute and chronic lesion dimensions on the esophagus. However, cryoablation was associated with a significantly lower risk of esophageal ulceration, compared with RF ablation. © 2007 by Futura Publishing Company, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/76863
ISSN
2015 Impact Factor: 3.097
2015 SCImago Journal Rankings: 1.863
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorRipley, KLen_HK
dc.contributor.authorGage, AAen_HK
dc.contributor.authorOlsen, DBen_HK
dc.contributor.authorVan Vleet, JFen_HK
dc.contributor.authorLau, CPen_HK
dc.contributor.authorTse, HFen_HK
dc.date.accessioned2010-09-06T07:25:43Z-
dc.date.available2010-09-06T07:25:43Z-
dc.date.issued2007en_HK
dc.identifier.citationJournal Of Cardiovascular Electrophysiology, 2007, v. 18 n. 6, p. 642-646en_HK
dc.identifier.issn1045-3873en_HK
dc.identifier.urihttp://hdl.handle.net/10722/76863-
dc.description.abstractBackground: Atrio-esophageal fistulas have been described as a consequence of radiofrequency (RF) ablation for the treatment of atrial fibrillation (AF). However, whether cryoablation can avoid this potential fatal complication remains unclear. Methods and Results: We studied the effects of direct application of RF and cryoablation on the cervical esophagus in 16 calves. Cryoablation was performed with a 6.5-mm catheter probe using a single 5-minute freeze at <-80°C, and RF ablation was delivered with an 8-mm catheter electrode at 50 W and 50°C for 45-60 seconds. Histopathologic assessments were performed at 1, 4, 7, and 14 day(s) after completion of the ablation protocol: four animals were examined each day. A total of 85 direct esophageal ablations were performed: 41 with RF and 44 with cryoablation. There were no significant differences in lesion width, depth, or volume between cryoablation and RF ablation at Day 1, 4, and 14 after the procedure (P > 0.05). However, lesion width and volume were significantly larger with RF than with cryoablation at Day 7. Although acute (Day 1) and chronic (Day 14) RF and cryoablation lesions were of comparable size, histologic evidence of partial- to full-wall esophageal lesion ulceration was observed in 0 of 44 (0%) lesions with cryoablation, compared with 9 of 41 (22%) lesions with RF ablation (P = 0.0025). Conclusions: Direct application of cryoablation and RF ablation created similar acute and chronic lesion dimensions on the esophagus. However, cryoablation was associated with a significantly lower risk of esophageal ulceration, compared with RF ablation. © 2007 by Futura Publishing Company, Inc.en_HK
dc.languageengen_HK
dc.publisherWiley-Blackwell Publishing, Inc.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=1045-3873en_HK
dc.relation.ispartofJournal of Cardiovascular Electrophysiologyen_HK
dc.subject.meshAnimalsen_HK
dc.subject.meshAtrial Fibrillation - surgeryen_HK
dc.subject.meshCatheter Ablation - adverse effectsen_HK
dc.subject.meshCattleen_HK
dc.subject.meshCryosurgery - adverse effectsen_HK
dc.subject.meshDisease Models, Animalen_HK
dc.subject.meshEsophageal Diseases - etiology - pathologyen_HK
dc.subject.meshEsophageal Fistula - etiologyen_HK
dc.subject.meshHeart Atria - injuriesen_HK
dc.subject.meshHeart Injuries - etiologyen_HK
dc.subject.meshMaleen_HK
dc.subject.meshNecrosisen_HK
dc.subject.meshTime Factorsen_HK
dc.titleTime course of esophageal lesions after catheter ablation with cryothermal and radiofrequency ablation: Implication for atrio-esophageal fistula formation after catheter ablation for atrial fibrillationen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1045-3873&volume=18&issue=6&spage=642&epage=6&date=2007&atitle=Time+course+of+esophageal+lesions+after+catheter+ablation+with+cryothermal+and+radiofrequency+ablation:+implication+for+atrio-esophageal+fistula+formation+after+catheter+ablation+for+atrial+fibrillation.en_HK
dc.identifier.emailTse, HF:hftse@hkucc.hku.hken_HK
dc.identifier.authorityTse, HF=rp00428en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1540-8167.2007.00790.xen_HK
dc.identifier.pmid17428270-
dc.identifier.scopuseid_2-s2.0-34249298673en_HK
dc.identifier.hkuros136562en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-34249298673&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume18en_HK
dc.identifier.issue6en_HK
dc.identifier.spage642en_HK
dc.identifier.epage646en_HK
dc.identifier.isiWOS:000246685400013-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridRipley, KL=6701380533en_HK
dc.identifier.scopusauthoridGage, AA=35478279100en_HK
dc.identifier.scopusauthoridOlsen, DB=36784520600en_HK
dc.identifier.scopusauthoridVan Vleet, JF=7005542715en_HK
dc.identifier.scopusauthoridLau, CP=7401968501en_HK
dc.identifier.scopusauthoridTse, HF=7006070805en_HK
dc.identifier.citeulike1334197-

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