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Article: Graphene-based high-efficiency surface-enhanced Raman scattering-active platform for sensitive and multiplex DNA detection

TitleGraphene-based high-efficiency surface-enhanced Raman scattering-active platform for sensitive and multiplex DNA detection
Authors
He, ShijiangLiu, Keng KuSu, ShaoYan, JuanMao, XiuhaiWang, DongfangHe, YaoLi, Lain JongSong, ShipingFan, Chunhai
Issue Date2012
Citation
Analytical Chemistry, 2012, v. 84, n. 10, p. 4622-4627 How to Cite?
DOI: http://dx.doi.org/10.1021/ac300577d
AbstractWe have developed a surface-enhanced Raman scattering (SERS)-active substrate based on gold nanoparticle-decorated chemical vapor deposition (CVD)-growth graphene and used it for multiplexing detection of DNA. Due to the combination of gold nanoparticles and graphene, the Raman signals of dye were dramatically enhanced by this novel substrate. With the gold nanoparticles, DNA capture probes could be easily assembled on the surface of graphene films which have a drawback to directly immobilize DNA. This platform exhibits extraordinarily high sensitivity and excellent specificity for DNA detection. A detection limit as low as 10 pM is obtained. Importantly, two different DNA targets could be detected simultaneously on the same substrate just using one light source. © 2012 American Chemical Society.
Persistent Identifierhttp://hdl.handle.net/10722/298559
ISSN
0003-2700
2021 Impact Factor: 8.008
2020 SCImago Journal Rankings: 2.117
ISI Accession Number ID
WOS:000303965500054

 

DC FieldValueLanguage
dc.contributor.authorHe, Shijiang-
dc.contributor.authorLiu, Keng Ku-
dc.contributor.authorSu, Shao-
dc.contributor.authorYan, Juan-
dc.contributor.authorMao, Xiuhai-
dc.contributor.authorWang, Dongfang-
dc.contributor.authorHe, Yao-
dc.contributor.authorLi, Lain Jong-
dc.contributor.authorSong, Shiping-
dc.contributor.authorFan, Chunhai-
dc.date.accessioned2021-04-08T03:08:45Z-
dc.date.available2021-04-08T03:08:45Z-
dc.date.issued2012-
dc.identifier.citationAnalytical Chemistry, 2012, v. 84, n. 10, p. 4622-4627-
dc.identifier.issn0003-2700-
dc.identifier.urihttp://hdl.handle.net/10722/298559-
dc.description.abstractWe have developed a surface-enhanced Raman scattering (SERS)-active substrate based on gold nanoparticle-decorated chemical vapor deposition (CVD)-growth graphene and used it for multiplexing detection of DNA. Due to the combination of gold nanoparticles and graphene, the Raman signals of dye were dramatically enhanced by this novel substrate. With the gold nanoparticles, DNA capture probes could be easily assembled on the surface of graphene films which have a drawback to directly immobilize DNA. This platform exhibits extraordinarily high sensitivity and excellent specificity for DNA detection. A detection limit as low as 10 pM is obtained. Importantly, two different DNA targets could be detected simultaneously on the same substrate just using one light source. © 2012 American Chemical Society.-
dc.languageeng-
dc.relation.ispartofAnalytical Chemistry-
dc.titleGraphene-based high-efficiency surface-enhanced Raman scattering-active platform for sensitive and multiplex DNA detection-
dc.typeArticle-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1021/ac300577d-
dc.identifier.pmid22497579-
dc.identifier.scopuseid_2-s2.0-84861109555-
dc.identifier.volume84-
dc.identifier.issue10-
dc.identifier.spage4622-
dc.identifier.epage4627-
dc.identifier.isiWOS:000303965500054-
dc.identifier.issnl0003-2700-

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