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Article: Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective

TitlePolysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective
Authors
Keywordspolysaccharide-based nanomaterials
polysaccharides
ocular drug delivery
nanocarriers
nano
Issue Date2020
PublisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/bioengineering_and_biotechnology
Citation
Frontiers in Bioengineering and Biotechnology, 2020, v. 8, p. article no. 601246 How to Cite?
AbstractOcular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues.
Persistent Identifierhttp://hdl.handle.net/10722/295498
ISSN
2021 Impact Factor: 6.064
2020 SCImago Journal Rankings: 1.081
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYu, H-
dc.contributor.authorWu, W-
dc.contributor.authorLin, X-
dc.contributor.authorFeng, Y-
dc.date.accessioned2021-01-25T11:15:45Z-
dc.date.available2021-01-25T11:15:45Z-
dc.date.issued2020-
dc.identifier.citationFrontiers in Bioengineering and Biotechnology, 2020, v. 8, p. article no. 601246-
dc.identifier.issn2296-4185-
dc.identifier.urihttp://hdl.handle.net/10722/295498-
dc.description.abstractOcular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues.-
dc.languageeng-
dc.publisherFrontiers Research Foundation. The Journal's web site is located at http://www.frontiersin.org/bioengineering_and_biotechnology-
dc.relation.ispartofFrontiers in Bioengineering and Biotechnology-
dc.rightsThis Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectpolysaccharide-based nanomaterials-
dc.subjectpolysaccharides-
dc.subjectocular drug delivery-
dc.subjectnanocarriers-
dc.subjectnano-
dc.titlePolysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective-
dc.typeArticle-
dc.identifier.emailLin, X: linxiang@hku.hk-
dc.identifier.authorityLin, X=rp02623-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3389/fbioe.2020.601246-
dc.identifier.pmid33363130-
dc.identifier.pmcidPMC7758246-
dc.identifier.scopuseid_2-s2.0-85098223099-
dc.identifier.hkuros321012-
dc.identifier.volume8-
dc.identifier.spagearticle no. 601246-
dc.identifier.epagearticle no. 601246-
dc.identifier.isiWOS:000601272300001-
dc.publisher.placeSwitzerland-

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