File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: A behavioral test battery for the repeated assessment of motor skills, mood, and cognition in mice

TitleA behavioral test battery for the repeated assessment of motor skills, mood, and cognition in mice
Authors
KeywordsAnxiety
Behavior
Cognition
Depression
Issue 145
Issue Date2019
PublisherJournal of Visualized Experiments. The Journal's web site is located at http://www.jove.com
Citation
Journal of Visualized Experiments, 2019, n. 145, article no. e58973 How to Cite?
AbstractPharmacological and toxicological studies in neurodegeneration require comprehensive behavioral analysis in mice because motor dysfunctions and dysfunctions in mood and cognition are common and often shared symptoms in neurodegenerative diseases. Shown here is a behavioral test battery for motor, mood, and cognition, which can be repeatedly tested in a longitudinal study. This battery assesses the overall behavioral phenotype in mice by examining each domain of behavior with at least two independent well-accepted tests (i.e., open-field test and rotarod test for motor function, social interaction test, elevated plus maze test, and forced swim test for emotional function, and Morris water maze test and novel object recognition test for cognitive function). Therefore, this sensitive and comprehensive test battery is a powerful tool for the study of behavioral alternation in neurodegeneration. © 2019 Journal of Visualized Experiments.
Persistent Identifierhttp://hdl.handle.net/10722/276230
ISSN
2019 Impact Factor: 1.163
2015 SCImago Journal Rankings: 0.451
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorYou, R-
dc.contributor.authorLiu, Y-
dc.contributor.authorChang, RCC-
dc.date.accessioned2019-09-10T02:58:38Z-
dc.date.available2019-09-10T02:58:38Z-
dc.date.issued2019-
dc.identifier.citationJournal of Visualized Experiments, 2019, n. 145, article no. e58973-
dc.identifier.issn1940-087X-
dc.identifier.urihttp://hdl.handle.net/10722/276230-
dc.description.abstractPharmacological and toxicological studies in neurodegeneration require comprehensive behavioral analysis in mice because motor dysfunctions and dysfunctions in mood and cognition are common and often shared symptoms in neurodegenerative diseases. Shown here is a behavioral test battery for motor, mood, and cognition, which can be repeatedly tested in a longitudinal study. This battery assesses the overall behavioral phenotype in mice by examining each domain of behavior with at least two independent well-accepted tests (i.e., open-field test and rotarod test for motor function, social interaction test, elevated plus maze test, and forced swim test for emotional function, and Morris water maze test and novel object recognition test for cognitive function). Therefore, this sensitive and comprehensive test battery is a powerful tool for the study of behavioral alternation in neurodegeneration. © 2019 Journal of Visualized Experiments.-
dc.languageeng-
dc.publisherJournal of Visualized Experiments. The Journal's web site is located at http://www.jove.com-
dc.relation.ispartofJournal of Visualized Experiments-
dc.rightsCopyright © 2019 Journal of Visualized Experiments.-
dc.subjectAnxiety-
dc.subjectBehavior-
dc.subjectCognition-
dc.subjectDepression-
dc.subjectIssue 145-
dc.titleA behavioral test battery for the repeated assessment of motor skills, mood, and cognition in mice-
dc.typeArticle-
dc.identifier.emailChang, RCC: rccchang@hku.hk-
dc.identifier.authorityChang, RCC=rp00470-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3791/58973-
dc.identifier.pmid30882789-
dc.identifier.scopuseid_2-s2.0-85063256391-
dc.identifier.hkuros303907-
dc.identifier.issue145-
dc.identifier.spagearticle no. e58973-
dc.identifier.epagearticle no. e58973-
dc.identifier.isiWOS:000462909500040-
dc.publisher.placeUnited States-
dc.identifier.issnl1940-087X-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats