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Article: Candida Tropicalis renal microabscesses in a child with leukemia confirmed using nucleic acid amplification and recovery after prolonged antifungal and corticosteroid treatment

TitleCandida Tropicalis renal microabscesses in a child with leukemia confirmed using nucleic acid amplification and recovery after prolonged antifungal and corticosteroid treatment
Authors
Rosa Duque, JAIME STo, KKWChiang, AKSChan, GCFPoon, WSRYuen, KYHa, SYCheuk, DKL
KeywordsCandida
Leukemia
Nucleic acid amplification
Polymerase chain reaction
Renal abscess
Issue Date2019
PublisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijid
Citation
International Journal of Infectious Diseases, 2019, v. 81, p. 110-113 How to Cite?
DOI: http://dx.doi.org/10.1016/j.ijid.2019.02.002
AbstractWe report the first case of microabscesses detected by polymerase chain reaction (PCR) amplification of nucleic acid from ultrasound-guided aspirated fluid in a three-year old boy with acute lymphoblastic leukemia and febrile neutropenia during induction chemotherapy. Fever persisted despite effective antifungal treatment. The addition of corticosteroid therapy successfully controlled the suspected immune reconstitution inflammatory syndrome (IRIS). This case highlights the utility of PCR and adjunctive corticosteroid in the approach of Candida tropicalis renal microabscesses in leukemic patients undergoing chemotherapy. © 2019 The Author(s)
Persistent Identifierhttp://hdl.handle.net/10722/273961
ISSN
1201-9712
2021 Impact Factor: 12.074
2020 SCImago Journal Rankings: 1.278
ISI Accession Number ID
WOS:000463889700023

 

DC FieldValueLanguage
dc.contributor.authorRosa Duque, JAIME S-
dc.contributor.authorTo, KKW-
dc.contributor.authorChiang, AKS-
dc.contributor.authorChan, GCF-
dc.contributor.authorPoon, WSR-
dc.contributor.authorYuen, KY-
dc.contributor.authorHa, SY-
dc.contributor.authorCheuk, DKL-
dc.date.accessioned2019-08-18T14:52:13Z-
dc.date.available2019-08-18T14:52:13Z-
dc.date.issued2019-
dc.identifier.citationInternational Journal of Infectious Diseases, 2019, v. 81, p. 110-113-
dc.identifier.issn1201-9712-
dc.identifier.urihttp://hdl.handle.net/10722/273961-
dc.description.abstractWe report the first case of microabscesses detected by polymerase chain reaction (PCR) amplification of nucleic acid from ultrasound-guided aspirated fluid in a three-year old boy with acute lymphoblastic leukemia and febrile neutropenia during induction chemotherapy. Fever persisted despite effective antifungal treatment. The addition of corticosteroid therapy successfully controlled the suspected immune reconstitution inflammatory syndrome (IRIS). This case highlights the utility of PCR and adjunctive corticosteroid in the approach of Candida tropicalis renal microabscesses in leukemic patients undergoing chemotherapy. © 2019 The Author(s)-
dc.languageeng-
dc.publisherElsevier Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijid-
dc.relation.ispartofInternational Journal of Infectious Diseases-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectCandida-
dc.subjectLeukemia-
dc.subjectNucleic acid amplification-
dc.subjectPolymerase chain reaction-
dc.subjectRenal abscess-
dc.titleCandida Tropicalis renal microabscesses in a child with leukemia confirmed using nucleic acid amplification and recovery after prolonged antifungal and corticosteroid treatment-
dc.typeArticle-
dc.identifier.emailTo, KKW: kelvinto@hku.hk-
dc.identifier.emailPoon, WSR: rosana@hkucc.hku.hk-
dc.identifier.emailYuen, KY: kyyuen@hkucc.hku.hk-
dc.identifier.authorityTo, KKW=rp01384-
dc.identifier.authorityYuen, KY=rp00366-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1016/j.ijid.2019.02.002-
dc.identifier.pmid30772467-
dc.identifier.scopuseid_2-s2.0-85061992511-
dc.identifier.hkuros301135-
dc.identifier.hkuros315814-
dc.identifier.hkuros317766-
dc.identifier.volume81-
dc.identifier.spage110-
dc.identifier.epage113-
dc.identifier.isiWOS:000463889700023-
dc.publisher.placeUnited Kingdom-
dc.identifier.issnl1201-9712-

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