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Article: Is Smoking a Risk Factor of Breast Cancer?

TitleIs Smoking a Risk Factor of Breast Cancer?
Authors
KeywordsBreast cancer
Risk factor
Smoking
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
Issue Date2019
PublisherCrimson Publishers, LLC. The Journal's web site is located at https://doi.org/10.31031/nacs
Citation
Novel Approaches in Cancer Study, 2019, v. 2 n. 3, p. article no. NACS.000540.2019 How to Cite?
AbstractThe incidence of breast cancer is increasing worldwide, making it the most common cancer among women. The etiology of breast cancer is multifactorial, including genetic risk factors, family history, age, gender, ethnicity, dense breast tissue and life-style related risk factors. Cigarette smoking is one of the risk factors in many cancers and recently been shown to be associated with breast cancer. The relationship between cigarette smoking and breast cancer has been explored in vitro and in vivo. One of the important components of cigarette smoke, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a representative carcinogen of N-nitrosamines, has also gained focus in breast cancer carcinogenesis. Other than promoting tumor growth in cancer cells, NNK has also been proved to cause malignant transformation in normal breast cells. However, clinical association of NNK and breast cells is still limited, and there are controversies that warrant further explorations
Persistent Identifierhttp://hdl.handle.net/10722/271308
ISSN

 

DC FieldValueLanguage
dc.contributor.authorGUAN, Z-
dc.contributor.authorCheuk, IW-
dc.contributor.authorShin, VY-
dc.contributor.authorKwong, A-
dc.date.accessioned2019-06-24T01:07:22Z-
dc.date.available2019-06-24T01:07:22Z-
dc.date.issued2019-
dc.identifier.citationNovel Approaches in Cancer Study, 2019, v. 2 n. 3, p. article no. NACS.000540.2019-
dc.identifier.issn2637-773X-
dc.identifier.urihttp://hdl.handle.net/10722/271308-
dc.description.abstractThe incidence of breast cancer is increasing worldwide, making it the most common cancer among women. The etiology of breast cancer is multifactorial, including genetic risk factors, family history, age, gender, ethnicity, dense breast tissue and life-style related risk factors. Cigarette smoking is one of the risk factors in many cancers and recently been shown to be associated with breast cancer. The relationship between cigarette smoking and breast cancer has been explored in vitro and in vivo. One of the important components of cigarette smoke, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a representative carcinogen of N-nitrosamines, has also gained focus in breast cancer carcinogenesis. Other than promoting tumor growth in cancer cells, NNK has also been proved to cause malignant transformation in normal breast cells. However, clinical association of NNK and breast cells is still limited, and there are controversies that warrant further explorations-
dc.languageeng-
dc.publisherCrimson Publishers, LLC. The Journal's web site is located at https://doi.org/10.31031/nacs-
dc.relation.ispartofNovel Approaches in Cancer Study-
dc.subjectBreast cancer-
dc.subjectRisk factor-
dc.subjectSmoking-
dc.subject4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-
dc.titleIs Smoking a Risk Factor of Breast Cancer?-
dc.typeArticle-
dc.identifier.emailCheuk, IW: isacheuk@hku.hk-
dc.identifier.emailShin, VY: vyshin@hku.hk-
dc.identifier.emailKwong, A: avakwong@hku.hk-
dc.identifier.authorityShin, VY=rp02000-
dc.identifier.authorityKwong, A=rp01734-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.31031/NACS.2019.02.000540-
dc.identifier.hkuros298161-
dc.identifier.hkuros298828-
dc.identifier.volume2-
dc.identifier.issue3-
dc.identifier.spagearticle no. NACS.000540.2019-
dc.identifier.epagearticle no. NACS.000540.2019-
dc.publisher.placeUnited States-

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