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Article: A Longitudinal Study on the Prevalence and Risk Factors for Depression and Anxiety, Quality of Life, and Clinical Outcomes in Incident Peritoneal Dialysis Patients

TitleA Longitudinal Study on the Prevalence and Risk Factors for Depression and Anxiety, Quality of Life, and Clinical Outcomes in Incident Peritoneal Dialysis Patients
Authors
KeywordsCommencement
Psychological symptoms
Issue Date2019
PublisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.com
Citation
Peritoneal Dialysis International, 2019, v. 39 n. 1, p. 74-82 How to Cite?
AbstractBackground: Starting dialysis is an important life event. The prevalence and evolution of psychological symptoms at commencement of long-term dialysis is unclear. We examined the prevalence of and risk factors for depression and anxiety, and the quality of life (QOL) of incident peritoneal dialysis (PD) patients, and also the change of these parameters in the first year of PD in relation to clinical outcomes under the PD-first policy. Methods: All patients commencing long-term PD from March 2011 to April 2015 were asked to complete the Hospital Anxiety and Depression Scale (HADS), World Health Organization Quality of Life-BREF and the Kidney Disease Quality of Life Instrument Short Form questionnaire. Patient demographics and the incidence of hospitalization, peritonitis, exit-site infection, and all-cause mortality were studied. The HADS was repeated after 9 – 12 months. Results: A high depression score was present in 39.6% of 191 patients at commencement of PD and was more common in diabetes patients (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.09 – 3.81). A high anxiety score was present in 23.6%, and the risk factors included younger age (OR 0.96 per year, 95% CI 0.94 – 0.99) and diabetes (OR 2.59, 95% CI 1.20 – 5.57). Both high depression and anxiety scores were associated with an inferior QOL, overall and across most QOL domains. Depression and anxiety symptoms did not change in the first year of PD and were not associated with short-term clinical outcomes. Conclusions: High depression and anxiety scores were prevalent in incident PD patients where PD-first policy is adopted and were associated with inferior QOL. There was no improvement after 1 year of PD. The impact of strategic interventions targeting patient groups at risk such as those with diabetes or of younger age warrants further investigation.
Persistent Identifierhttp://hdl.handle.net/10722/260527
ISSN
2017 Impact Factor: 2.009
2015 SCImago Journal Rankings: 0.683
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorMok, MYM-
dc.contributor.authorLiu, CK-
dc.contributor.authorLam, MF-
dc.contributor.authorKwan, LPY-
dc.contributor.authorChan, GC-
dc.contributor.authorMa, KMM-
dc.contributor.authorYap, YHD-
dc.contributor.authorChiu, F-
dc.contributor.authorChoy, CB-
dc.contributor.authorTang, SCW-
dc.contributor.authorChan, DTM-
dc.date.accessioned2018-09-14T08:43:09Z-
dc.date.available2018-09-14T08:43:09Z-
dc.date.issued2019-
dc.identifier.citationPeritoneal Dialysis International, 2019, v. 39 n. 1, p. 74-82-
dc.identifier.issn0896-8608-
dc.identifier.urihttp://hdl.handle.net/10722/260527-
dc.description.abstractBackground: Starting dialysis is an important life event. The prevalence and evolution of psychological symptoms at commencement of long-term dialysis is unclear. We examined the prevalence of and risk factors for depression and anxiety, and the quality of life (QOL) of incident peritoneal dialysis (PD) patients, and also the change of these parameters in the first year of PD in relation to clinical outcomes under the PD-first policy. Methods: All patients commencing long-term PD from March 2011 to April 2015 were asked to complete the Hospital Anxiety and Depression Scale (HADS), World Health Organization Quality of Life-BREF and the Kidney Disease Quality of Life Instrument Short Form questionnaire. Patient demographics and the incidence of hospitalization, peritonitis, exit-site infection, and all-cause mortality were studied. The HADS was repeated after 9 – 12 months. Results: A high depression score was present in 39.6% of 191 patients at commencement of PD and was more common in diabetes patients (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.09 – 3.81). A high anxiety score was present in 23.6%, and the risk factors included younger age (OR 0.96 per year, 95% CI 0.94 – 0.99) and diabetes (OR 2.59, 95% CI 1.20 – 5.57). Both high depression and anxiety scores were associated with an inferior QOL, overall and across most QOL domains. Depression and anxiety symptoms did not change in the first year of PD and were not associated with short-term clinical outcomes. Conclusions: High depression and anxiety scores were prevalent in incident PD patients where PD-first policy is adopted and were associated with inferior QOL. There was no improvement after 1 year of PD. The impact of strategic interventions targeting patient groups at risk such as those with diabetes or of younger age warrants further investigation.-
dc.languageeng-
dc.publisherMultimed, Inc. The Journal's web site is located at http://pdiconnect.com-
dc.relation.ispartofPeritoneal Dialysis International-
dc.subjectCommencement-
dc.subjectPsychological symptoms-
dc.titleA Longitudinal Study on the Prevalence and Risk Factors for Depression and Anxiety, Quality of Life, and Clinical Outcomes in Incident Peritoneal Dialysis Patients-
dc.typeArticle-
dc.identifier.emailMa, KMM: h9914584@graduate.hku.hk-
dc.identifier.emailYap, YHD: desmondy@hku.hk-
dc.identifier.emailTang, SCW: scwtang@hku.hk-
dc.identifier.emailChan, DTM: dtmchan@hkucc.hku.hk-
dc.identifier.authorityYap, YHD=rp01607-
dc.identifier.authorityTang, SCW=rp00480-
dc.identifier.authorityChan, DTM=rp00394-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.3747/pdi.2017.00168-
dc.identifier.pmid29991560-
dc.identifier.scopuseid_2-s2.0-85058956841-
dc.identifier.hkuros290771-
dc.identifier.hkuros287994-
dc.identifier.volume39-
dc.identifier.issue1-
dc.identifier.spage74-
dc.identifier.epage82-
dc.identifier.isiWOS:000456823000011-
dc.publisher.placeCanada-

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