File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils

TitleBudding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils
Authors
Issue Date2018
PublisherNature Publishing Group: Nature Communications. The Journal's web site is located at http://www.nature.com/ncomms/index.html
Citation
Nature Communications, 2018, v. 9, p. 2110 How to Cite?
AbstractNetworks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of all-aqueous emulsion droplets with budding-like morphologies. We show that this process is driven by the difference in the immersional wetting energy of the nanofibril network, and that both the size and the number of the daughter droplets formed during division can be controlled by modulating the fibril concentration and the chemical properties of the fibril network. Our results demonstrate a route for achieving biomimetic division with synthetic self-assembling fibrils and offer an engineered approach to regulate the morphology of protein gels.
Persistent Identifierhttp://hdl.handle.net/10722/260323
ISSN
2017 Impact Factor: 12.353
2015 SCImago Journal Rankings: 6.539

 

DC FieldValueLanguage
dc.contributor.authorSong, Y-
dc.contributor.authorMichaels, TCT-
dc.contributor.authorMa, QM-
dc.contributor.authorLiu, Z-
dc.contributor.authorYuan, H-
dc.contributor.authorTakayama, S-
dc.contributor.authorKnowles, TPJ-
dc.contributor.authorShum, HC-
dc.date.accessioned2018-09-14T08:39:45Z-
dc.date.available2018-09-14T08:39:45Z-
dc.date.issued2018-
dc.identifier.citationNature Communications, 2018, v. 9, p. 2110-
dc.identifier.issn2041-1723-
dc.identifier.urihttp://hdl.handle.net/10722/260323-
dc.description.abstractNetworks of natural protein nanofibrils, such as cytoskeletal filaments, control the shape and the division of cells, yet mimicking this functionality in a synthetic setting has proved challenging. Here, we demonstrate that artificial networks of protein nanofibrils can induce controlled deformation and division of all-aqueous emulsion droplets with budding-like morphologies. We show that this process is driven by the difference in the immersional wetting energy of the nanofibril network, and that both the size and the number of the daughter droplets formed during division can be controlled by modulating the fibril concentration and the chemical properties of the fibril network. Our results demonstrate a route for achieving biomimetic division with synthetic self-assembling fibrils and offer an engineered approach to regulate the morphology of protein gels.-
dc.languageeng-
dc.publisherNature Publishing Group: Nature Communications. The Journal's web site is located at http://www.nature.com/ncomms/index.html-
dc.relation.ispartofNature Communications-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleBudding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils-
dc.typeArticle-
dc.identifier.emailShum, HC: ashum@hku.hk-
dc.identifier.authorityShum, HC=rp01439-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1038/s41467-018-04510-3-
dc.identifier.hkuros290227-
dc.identifier.volume9-
dc.identifier.spage2110-
dc.identifier.epage2110-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats