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Article: The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases

TitleThe Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases
Authors
Issue Date2018
PublisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/oximed/
Citation
Oxidative Medicine and Cellular Longevity, 2018, v. 4, p. 8394818:1-8394818:25 How to Cite?
AbstractLiver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In recent years, many natural foods and herbs with abundant phytochemicals have been proposed as health supplementation for patients with hepatic disorders. As an important category of phytochemicals, natural polyphenols have attracted increasing attention as potential agents for the prevention and treatment of liver diseases. The striking capacities in remitting oxidative stress, lipid metabolism, insulin resistance, and inflammation put polyphenols in the spotlight for the therapies of liver diseases. It has been reported that many polyphenols from a wide range of foods and herbs exert therapeutic effects on liver injuries via complicated mechanisms. Therefore, it is necessary to have a systematical review to sort out current researches to help better understand the potentials of polyphenols in liver diseases. In this review, we aim to summarize and update the existing evidence of natural polyphenols in the treatment of various liver diseases by in vitro, in vivo, and clinical studies, while special attention is paid to the action mechanisms.
Persistent Identifierhttp://hdl.handle.net/10722/259993
ISSN
2015 Impact Factor: 4.492
2015 SCImago Journal Rankings: 1.503

 

DC FieldValueLanguage
dc.contributor.authorLI, S-
dc.contributor.authorTan, HYH-
dc.contributor.authorWang, N-
dc.contributor.authorCheung, F-
dc.contributor.authorHONG, M-
dc.contributor.authorFeng, Y-
dc.date.accessioned2018-09-03T04:22:41Z-
dc.date.available2018-09-03T04:22:41Z-
dc.date.issued2018-
dc.identifier.citationOxidative Medicine and Cellular Longevity, 2018, v. 4, p. 8394818:1-8394818:25-
dc.identifier.issn1942-0900-
dc.identifier.urihttp://hdl.handle.net/10722/259993-
dc.description.abstractLiver disease, involving a wide range of liver pathologies from fatty liver, hepatitis, and fibrosis to cirrhosis and hepatocellular carcinoma, is a serious health problem worldwide. In recent years, many natural foods and herbs with abundant phytochemicals have been proposed as health supplementation for patients with hepatic disorders. As an important category of phytochemicals, natural polyphenols have attracted increasing attention as potential agents for the prevention and treatment of liver diseases. The striking capacities in remitting oxidative stress, lipid metabolism, insulin resistance, and inflammation put polyphenols in the spotlight for the therapies of liver diseases. It has been reported that many polyphenols from a wide range of foods and herbs exert therapeutic effects on liver injuries via complicated mechanisms. Therefore, it is necessary to have a systematical review to sort out current researches to help better understand the potentials of polyphenols in liver diseases. In this review, we aim to summarize and update the existing evidence of natural polyphenols in the treatment of various liver diseases by in vitro, in vivo, and clinical studies, while special attention is paid to the action mechanisms.-
dc.languageeng-
dc.publisherHindawi Publishing Corporation. The Journal's web site is located at http://www.hindawi.com/journals/oximed/-
dc.relation.ispartofOxidative Medicine and Cellular Longevity-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleThe Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases-
dc.typeArticle-
dc.identifier.emailTan, HYH: hyhtan@hku.hk-
dc.identifier.emailWang, N: ckwang@hku.hk-
dc.identifier.emailCheung, F: ofcheung@hku.hk-
dc.identifier.emailFeng, Y: yfeng@hku.hk-
dc.identifier.authorityWang, N=rp02075-
dc.identifier.authorityFeng, Y=rp00466-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1155/2018/8394818-
dc.identifier.hkuros288790-
dc.identifier.volume4-
dc.identifier.spage8394818:1-
dc.identifier.epage8394818:25-
dc.publisher.placeUnited States-

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