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Article: Methylphenidate for ADHD in children and adolescents: Throwing the baby out with the bathwater

TitleMethylphenidate for ADHD in children and adolescents: Throwing the baby out with the bathwater
Authors
Issue Date2016
PublisherB M J Group. The Journal's web site is located at https://ebmh.bmj.com/
Citation
Evidence-Based Mental Health, 2016, v. 19 n. 4, p. 97-99 How to Cite?
AbstractA recent Cochrane review assessed the efficacy of methylphenidate for attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. Notwithstanding the moderate-to-large effect sizes for ADHD symptom reduction found in the meta-analysis, the authors concluded that the quality of the evidence is low and therefore the true magnitude of these effects remains uncertain. We identified a number of major concerns with the review, in the domains of study inclusion, approaches to quality assessment and interpretation of data relating to serious adverse events as well as of the clinical implications of the reported effects. We also found errors in the extraction of data used to estimate the effect size of the primary outcome. Considering all the shortcomings, the conclusion in the Cochrane review that the status of the evidence is uncertain is misplaced. Professionals, parents and patients should refer to previous reviews and existing guidelines, which include methylphenidate as one of the safe and efficacious treatment strategies for ADHD.
Persistent Identifierhttp://hdl.handle.net/10722/259429
ISSN
2015 SCImago Journal Rankings: 0.217

 

DC FieldValueLanguage
dc.contributor.authorBanaschewski, T-
dc.contributor.authorBuitelaar, J-
dc.contributor.authorChui, SLC-
dc.contributor.authorCoghill, D-
dc.contributor.authorCortese, S-
dc.contributor.authorSimonoff, E-
dc.contributor.authorWong, ICK-
dc.date.accessioned2018-09-03T04:07:16Z-
dc.date.available2018-09-03T04:07:16Z-
dc.date.issued2016-
dc.identifier.citationEvidence-Based Mental Health, 2016, v. 19 n. 4, p. 97-99-
dc.identifier.issn1362-0347-
dc.identifier.urihttp://hdl.handle.net/10722/259429-
dc.description.abstractA recent Cochrane review assessed the efficacy of methylphenidate for attention-deficit/hyperactivity disorder (ADHD) in children and adolescents. Notwithstanding the moderate-to-large effect sizes for ADHD symptom reduction found in the meta-analysis, the authors concluded that the quality of the evidence is low and therefore the true magnitude of these effects remains uncertain. We identified a number of major concerns with the review, in the domains of study inclusion, approaches to quality assessment and interpretation of data relating to serious adverse events as well as of the clinical implications of the reported effects. We also found errors in the extraction of data used to estimate the effect size of the primary outcome. Considering all the shortcomings, the conclusion in the Cochrane review that the status of the evidence is uncertain is misplaced. Professionals, parents and patients should refer to previous reviews and existing guidelines, which include methylphenidate as one of the safe and efficacious treatment strategies for ADHD.-
dc.languageeng-
dc.publisherB M J Group. The Journal's web site is located at https://ebmh.bmj.com/-
dc.relation.ispartofEvidence-Based Mental Health-
dc.rightsEvidence-Based Mental Health. Copyright © B M J Group.-
dc.subject.meshAdolescent-
dc.subject.meshAttention Deficit Disorder with Hyperactivity-
dc.subject.meshChild-
dc.subject.meshHumans-
dc.subject.meshMethylphenidate-
dc.titleMethylphenidate for ADHD in children and adolescents: Throwing the baby out with the bathwater-
dc.typeArticle-
dc.identifier.emailWong, ICK: wongick@hku.hk-
dc.identifier.authorityWong, ICK=rp01480-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1136/eb-2016-102461-
dc.identifier.pmid27935807-
dc.identifier.scopuseid_2-s2.0-84991728605-
dc.identifier.hkuros287773-
dc.identifier.volume19-
dc.identifier.issue4-
dc.identifier.spage97-
dc.identifier.epage99-
dc.publisher.placeUnited Kingdom-

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