Article: Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial

TitleCombined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial
Authors
KeywordsRCT
Health economic analysis
Placebo
Analgesia
Morphine consumption
Issue Date2018
PublisherBioMed Central Ltd. The Journal's web site is located at http://www.trialsjournal.com/
Citation
Trials, 2018, v. 19, p. 8 How to Cite?
AbstractBackground: Postoperative pain is a major complaint following abdominal surgery for gynecological diseases. Effective postoperative pain control after abdominal surgery is particularly important for patient recovery, mobility, and satisfaction. Acupuncture has been commonly used for pain management. However, its efficacy in postoperative pain control is inconclusive and health economic evaluation is limited. Methods: A randomized, sham-controlled, patient- and- assessor-blind trial is designed to evaluate the efficacy and safety of acupuncture in managing postoperative pain following abdominal surgery of gynecological diseases. Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine mass, and cervical lesions, will be recruited. Seventy-two participants will be randomly allocated to an acupuncture or non-invasive sham control in a 1:1 ratio. Treatment will be done within 2 h before operation, upon arrival to the ward and once daily for 5 days. The Pain Numerical Rating Scale (NRS) on the first 5 days during hospitalization will be the primary outcome and will be analyzed using the area-under-the-curve (AUC) method. The secondary outcome measures include frequency of rescue analgesic use during hospital stay, cumulative morphine consumption; quality of recovery as measured by time to recovery variables and the Quality of Recovery-9 (QoR-9); quality of life as measured by the Short Form-6 dimension (SF-6D) and EuroQol-5 Dimension-5 Level (EQ-5D-5 L). The incremental cost-effectiveness ratio of acupuncture vs sham acupuncture will be calculated. Discussion: This study protocol provides an example of integrative medicine practice in a hospital setting for the management of postoperative pain using acupuncture treatment. The acupuncture treatment protocol, if proven to be effective, can be implemented in routine settings to play a role in postoperative pain management for patients who have undergone abdominal surgery for gynecological diseases.
Persistent Identifierhttp://hdl.handle.net/10722/250533
ISSN
2017 Impact Factor: 2.067
2015 SCImago Journal Rankings: 1.077
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLam, WL-
dc.contributor.authorYeung, WF-
dc.contributor.authorWong, MK-
dc.contributor.authorCheung, CW-
dc.contributor.authorChan, KKL-
dc.contributor.authorNgan, HYS-
dc.contributor.authorWong, CKH-
dc.contributor.authorChen, H-
dc.contributor.authorLao, L-
dc.date.accessioned2018-01-18T04:28:35Z-
dc.date.available2018-01-18T04:28:35Z-
dc.date.issued2018-
dc.identifier.citationTrials, 2018, v. 19, p. 8-
dc.identifier.issn1745-6215-
dc.identifier.urihttp://hdl.handle.net/10722/250533-
dc.description.abstractBackground: Postoperative pain is a major complaint following abdominal surgery for gynecological diseases. Effective postoperative pain control after abdominal surgery is particularly important for patient recovery, mobility, and satisfaction. Acupuncture has been commonly used for pain management. However, its efficacy in postoperative pain control is inconclusive and health economic evaluation is limited. Methods: A randomized, sham-controlled, patient- and- assessor-blind trial is designed to evaluate the efficacy and safety of acupuncture in managing postoperative pain following abdominal surgery of gynecological diseases. Patients who are eligible for laparotomy with a midline incision for gynecological neoplasia, including ovarian mass, uterine mass, and cervical lesions, will be recruited. Seventy-two participants will be randomly allocated to an acupuncture or non-invasive sham control in a 1:1 ratio. Treatment will be done within 2 h before operation, upon arrival to the ward and once daily for 5 days. The Pain Numerical Rating Scale (NRS) on the first 5 days during hospitalization will be the primary outcome and will be analyzed using the area-under-the-curve (AUC) method. The secondary outcome measures include frequency of rescue analgesic use during hospital stay, cumulative morphine consumption; quality of recovery as measured by time to recovery variables and the Quality of Recovery-9 (QoR-9); quality of life as measured by the Short Form-6 dimension (SF-6D) and EuroQol-5 Dimension-5 Level (EQ-5D-5 L). The incremental cost-effectiveness ratio of acupuncture vs sham acupuncture will be calculated. Discussion: This study protocol provides an example of integrative medicine practice in a hospital setting for the management of postoperative pain using acupuncture treatment. The acupuncture treatment protocol, if proven to be effective, can be implemented in routine settings to play a role in postoperative pain management for patients who have undergone abdominal surgery for gynecological diseases.-
dc.languageeng-
dc.publisherBioMed Central Ltd. The Journal's web site is located at http://www.trialsjournal.com/-
dc.relation.ispartofTrials-
dc.rightsTrials. Copyright © BioMed Central Ltd.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectRCT-
dc.subjectHealth economic analysis-
dc.subjectPlacebo-
dc.subjectAnalgesia-
dc.subjectMorphine consumption-
dc.titleCombined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial-
dc.typeArticle-
dc.identifier.emailLam, WL: wlpop@hku.hk-
dc.identifier.emailYeung, WF: yeungwfj@hku.hk-
dc.identifier.emailCheung, CW: cheucw@hku.hk-
dc.identifier.emailChan, KKL: kklchan@hkucc.hku.hk-
dc.identifier.emailNgan, HYS: hysngan@hkucc.hku.hk-
dc.identifier.emailWong, CKH: carlosho@hku.hk-
dc.identifier.emailChen, H: haiyong@hku.hk-
dc.identifier.emailLao, L: lxlao1@hku.hk-
dc.identifier.authorityYeung, WF=rp01901-
dc.identifier.authorityCheung, CW=rp00244-
dc.identifier.authorityChan, KKL=rp00499-
dc.identifier.authorityNgan, HYS=rp00346-
dc.identifier.authorityWong, CKH=rp01931-
dc.identifier.authorityChen, H=rp01923-
dc.identifier.authorityLao, L=rp01784-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1186/s13063-017-2359-8-
dc.identifier.pmcidPMC5755011-
dc.identifier.hkuros284026-
dc.identifier.volume19-
dc.identifier.spage8-
dc.identifier.epage8-
dc.identifier.isiWOS:000419607200007-
dc.publisher.placeUnited Kingdom-

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