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Article: Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines

TitleDelineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines
Authors
KeywordsClinical Target Volume (CTV)
Gross Tumour Volume (GTV)
Radiotherapy
Head and neck
Guideline
Issue Date2018
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/radonc
Citation
Radiotherapy & Oncology, 2018, v. 126 n. 1, p. 3-24 How to Cite?
AbstractPurpose: Few studies have reported large inter-observer variations in target volume selection and delineation in patients treated with radiotherapy for head and neck squamous cell carcinoma. Consensus guidelines have been published for the neck nodes (see Grégoire et al., 2003, 2014), but such recommendations are lacking for primary tumour delineation. For the latter, two main schools of thoughts are prevailing, one based on geometric expansion of the Gross Tumour Volume (GTV) as promoted by DAHANCA, and the other one based on anatomical expansion of the GTV using compartmentalization of head and neck anatomy. Method: For each anatomic location within the larynx, hypopharynx, oropharynx and oral cavity, and for each T-stage, the DAHANCA proposal has been comprehensively reviewed and edited to include anatomic knowledge into the geometric Clinical Target Volume (CTV) delineation concept. A first proposal was put forward by the leading authors of this publication (VG and CG) and discussed with opinion leaders in head and neck radiation oncology from Europe, Asia, Australia/New Zealand, North America and South America to reach a worldwide consensus. Results: This consensus proposes two CTVs for the primary tumour, the so called CTV-P1 and CVT-P2, corresponding to a high and lower tumour burden, and which should be associated with a high and a lower dose prescription, respectively. Conclusion: Implementation of these guidelines in the daily practice of radiation oncology should contribute to reduce treatment variations from clinicians to clinicians, facilitate the conduct of multi-institutional clinical trials, and contribute to improved care of patients with head and neck carcinoma.
Persistent Identifierhttp://hdl.handle.net/10722/249993
ISSN
2017 Impact Factor: 4.942
2015 SCImago Journal Rankings: 2.654
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorGrégoire, V-
dc.contributor.authorEvans, M-
dc.contributor.authorLe, QT-
dc.contributor.authorBourhis, J-
dc.contributor.authorBudach, V-
dc.contributor.authorChen, A-
dc.contributor.authorEisbruch, A-
dc.contributor.authorFeng, M-
dc.contributor.authorGiralt, J-
dc.contributor.authorGupta, T-
dc.contributor.authorHamoir, M-
dc.contributor.authorHelito, JK-
dc.contributor.authorHu, C-
dc.contributor.authorHunter, K-
dc.contributor.authorJohansen, J-
dc.contributor.authorKaanders, J-
dc.contributor.authorLaskar, SG-
dc.contributor.authorLee, WMA-
dc.contributor.authorMaingon, P-
dc.contributor.authorMäkitie, A-
dc.contributor.authorMicciche', F-
dc.contributor.authorNicolai, P-
dc.contributor.authorO'Sullivan, B-
dc.contributor.authorPoitevin, A-
dc.contributor.authorPorceddu, S-
dc.contributor.authorSkładowski, K-
dc.contributor.authorTribius, S-
dc.contributor.authorWaldron, J-
dc.contributor.authorWee, J-
dc.contributor.authorYao, M-
dc.contributor.authorYom, M-
dc.contributor.authorZimmermann, F-
dc.contributor.authorCrau, C-
dc.date.accessioned2017-12-20T09:19:06Z-
dc.date.available2017-12-20T09:19:06Z-
dc.date.issued2018-
dc.identifier.citationRadiotherapy & Oncology, 2018, v. 126 n. 1, p. 3-24-
dc.identifier.issn0167-8140-
dc.identifier.urihttp://hdl.handle.net/10722/249993-
dc.description.abstractPurpose: Few studies have reported large inter-observer variations in target volume selection and delineation in patients treated with radiotherapy for head and neck squamous cell carcinoma. Consensus guidelines have been published for the neck nodes (see Grégoire et al., 2003, 2014), but such recommendations are lacking for primary tumour delineation. For the latter, two main schools of thoughts are prevailing, one based on geometric expansion of the Gross Tumour Volume (GTV) as promoted by DAHANCA, and the other one based on anatomical expansion of the GTV using compartmentalization of head and neck anatomy. Method: For each anatomic location within the larynx, hypopharynx, oropharynx and oral cavity, and for each T-stage, the DAHANCA proposal has been comprehensively reviewed and edited to include anatomic knowledge into the geometric Clinical Target Volume (CTV) delineation concept. A first proposal was put forward by the leading authors of this publication (VG and CG) and discussed with opinion leaders in head and neck radiation oncology from Europe, Asia, Australia/New Zealand, North America and South America to reach a worldwide consensus. Results: This consensus proposes two CTVs for the primary tumour, the so called CTV-P1 and CVT-P2, corresponding to a high and lower tumour burden, and which should be associated with a high and a lower dose prescription, respectively. Conclusion: Implementation of these guidelines in the daily practice of radiation oncology should contribute to reduce treatment variations from clinicians to clinicians, facilitate the conduct of multi-institutional clinical trials, and contribute to improved care of patients with head and neck carcinoma.-
dc.languageeng-
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/radonc-
dc.relation.ispartofRadiotherapy & Oncology-
dc.subjectClinical Target Volume (CTV)-
dc.subjectGross Tumour Volume (GTV)-
dc.subjectRadiotherapy-
dc.subjectHead and neck-
dc.subjectGuideline-
dc.titleDelineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines-
dc.typeArticle-
dc.identifier.emailLee, WMA: awmlee@hkucc.hku.hk-
dc.identifier.authorityLee, WMA=rp02056-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.radonc.2017.10.016-
dc.identifier.pmid29180076-
dc.identifier.hkuros283796-
dc.identifier.volume126-
dc.identifier.issue1-
dc.identifier.spage3-
dc.identifier.epage24-
dc.identifier.isiWOS:000425578100002-
dc.publisher.placeIreland-

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