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Article: In Vitro Activity of Posaconazole against Talaromyces marneffei by Broth Microdilution and Etest Methods and Comparison to Itraconazole, Voriconazole, and Anidulafungin

TitleIn Vitro Activity of Posaconazole against Talaromyces marneffei by Broth Microdilution and Etest Methods and Comparison to Itraconazole, Voriconazole, and Anidulafungin
Authors
KeywordsEtest
Penicillium
Talaromyces marneffei
Anidulafungin
Itraconazole
Issue Date2017
PublisherAmerican Society for Microbiology. The Journal's web site is located at http://aac.asm.org/
Citation
Antimicrobial Agents and Chemotherapy, 2017, v. 61 n. 3, article no. e01480-16 How to Cite?
AbstractWe determined the susceptibilities of 57 Talaromyces marneffei strains to anidulafungin, itraconazole, voriconazole, and posaconazole with MICs of 2 to 8, 0.002 to 0.004, 0.016 to 0.063, and 0.001 to 0.002 μg/ml by broth microdilution and >32, ≤0.002 to 0.008, ≤0.002 to 0.008, and ≤0.002 μg/ml by Etest, respectively, at yeast phase; MICs at mycelial phase for anidulafungin and posaconazole were 1 to 2 and 0.004 to 0.063 μg/ml, respectively. The results suggest promising activities of posaconazole. Etest can be used for testing of azoles against T. marneffei.
Persistent Identifierhttp://hdl.handle.net/10722/245144
ISSN
2017 Impact Factor: 4.256
2015 SCImago Journal Rankings: 2.322
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLau, SKP-
dc.contributor.authorLo, CS-
dc.contributor.authorLam, CS-
dc.contributor.authorChow, WN-
dc.contributor.authorNgan, AH-
dc.contributor.authorWu, AK-
dc.contributor.authorTsang, DN-
dc.contributor.authorTse, CW-
dc.contributor.authorQue, TL-
dc.contributor.authorTang, BS-
dc.contributor.authorWoo, PCY-
dc.date.accessioned2017-09-18T02:05:25Z-
dc.date.available2017-09-18T02:05:25Z-
dc.date.issued2017-
dc.identifier.citationAntimicrobial Agents and Chemotherapy, 2017, v. 61 n. 3, article no. e01480-16-
dc.identifier.issn0066-4804-
dc.identifier.urihttp://hdl.handle.net/10722/245144-
dc.description.abstractWe determined the susceptibilities of 57 Talaromyces marneffei strains to anidulafungin, itraconazole, voriconazole, and posaconazole with MICs of 2 to 8, 0.002 to 0.004, 0.016 to 0.063, and 0.001 to 0.002 μg/ml by broth microdilution and >32, ≤0.002 to 0.008, ≤0.002 to 0.008, and ≤0.002 μg/ml by Etest, respectively, at yeast phase; MICs at mycelial phase for anidulafungin and posaconazole were 1 to 2 and 0.004 to 0.063 μg/ml, respectively. The results suggest promising activities of posaconazole. Etest can be used for testing of azoles against T. marneffei.-
dc.languageeng-
dc.publisherAmerican Society for Microbiology. The Journal's web site is located at http://aac.asm.org/-
dc.relation.ispartofAntimicrobial Agents and Chemotherapy-
dc.rightsAntimicrobial Agents and Chemotherapy. Copyright © American Society for Microbiology.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectEtest-
dc.subjectPenicillium-
dc.subjectTalaromyces marneffei-
dc.subjectAnidulafungin-
dc.subjectItraconazole-
dc.titleIn Vitro Activity of Posaconazole against Talaromyces marneffei by Broth Microdilution and Etest Methods and Comparison to Itraconazole, Voriconazole, and Anidulafungin-
dc.typeArticle-
dc.identifier.emailLau, SKP: skplau@hkucc.hku.hk-
dc.identifier.emailLo, CS: gcslo@connect.hku.hk-
dc.identifier.emailWoo, PCY: pcywoo@hkucc.hku.hk-
dc.identifier.authorityLau, SKP=rp00486-
dc.identifier.authorityChow, WN=rp02493-
dc.identifier.authorityWoo, PCY=rp00430-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1128/AAC.01480-16-
dc.identifier.pmid28031205-
dc.identifier.pmcidPMC5328531-
dc.identifier.scopuseid_2-s2.0-85014119584-
dc.identifier.hkuros275895-
dc.identifier.volume61-
dc.identifier.issue3-
dc.identifier.spagee01480-
dc.identifier.epage16-
dc.identifier.isiWOS:000394605900030-
dc.publisher.placeUnited States-

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