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Article: Angiographic study of the clinical liaison of drug-eluting stent and paclitaxel-eluting balloon in unifocal side branch ostium stenosis (ASCLEPIUS)

TitleAngiographic study of the clinical liaison of drug-eluting stent and paclitaxel-eluting balloon in unifocal side branch ostium stenosis (ASCLEPIUS)
Authors
KeywordsBifurcation stenosis
Drug-eluting stent
Isolated side branch ostium stenosis
Paclitaxel-eluting balloon
Percutaneous coronary intervention
Restenosis
Issue Date2017
PublisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327
Citation
Heart and Vessels, 2017, v. 32 n. 9, p. 1045-1050 How to Cite?
AbstractA reliable stenting strategy for treating isolated side branch (SB) ostium stenosis is not well established. The purpose of this study was to examine the 6-month angiographic outcome of a novel technique, called the shoulder technique, on this lesion subtype. Symptomatic patients with isolated SB ostium stenosis, defined as ≥75% diameter stenosis at SB ostium and <50% diameter stenosis in main vessel (MV), were treated with paclitaxel-eluting balloon in MV and drug-eluting stent in SB using the shoulder technique. Angiographic restudy was performed at 5–9 months and clinical follow-up was scheduled regularly every 3 months. There were 46 patients of age 66 ± 12 years with male predominance (76%) recruited. Diagonal ostium (67%) was the most frequent target lesion site. The size and length of paclitaxel-eluting balloon and drug-eluting stent used in MV and SB were 3.01 ± 0.25 and 20 ± 4 mm, and 2.39 ± 0.25 and 17 ± 6 mm, respectively. Angiographic restudy was performed on 43 (93.5%) patients at 6.5 ± 1.6 months. The late loss in MV and SB were 0.04 ± 0.19 and 0.19 ± 0.32 mm, respectively. Angiographic restensosis was seen in 2 (4.7%) patients at SB, whereas no stenosis was induced in MV. Improvement of symptom was reported in 36 (78%) patients. At 1-year follow-up, no death, myocardial infarction, and stent thrombosis was observed; target vessel revascularization was performed on 3 (6.5%) patients. Treatment of isolated SB ostium stenosis using the shoulder technique is associated with a favorable short-term angiographic outcome. © 2017, Springer Japan.
Persistent Identifierhttp://hdl.handle.net/10722/243171
ISSN
2017 Impact Factor: 2.185
2015 SCImago Journal Rankings: 0.709
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJim, MH-
dc.contributor.authorWu, EB-
dc.contributor.authorChan, CY-
dc.contributor.authorWong, KL-
dc.contributor.authorFung, RC-
dc.contributor.authorYiu, KH-
dc.date.accessioned2017-08-25T02:51:05Z-
dc.date.available2017-08-25T02:51:05Z-
dc.date.issued2017-
dc.identifier.citationHeart and Vessels, 2017, v. 32 n. 9, p. 1045-1050-
dc.identifier.issn0910-8327-
dc.identifier.urihttp://hdl.handle.net/10722/243171-
dc.description.abstractA reliable stenting strategy for treating isolated side branch (SB) ostium stenosis is not well established. The purpose of this study was to examine the 6-month angiographic outcome of a novel technique, called the shoulder technique, on this lesion subtype. Symptomatic patients with isolated SB ostium stenosis, defined as ≥75% diameter stenosis at SB ostium and <50% diameter stenosis in main vessel (MV), were treated with paclitaxel-eluting balloon in MV and drug-eluting stent in SB using the shoulder technique. Angiographic restudy was performed at 5–9 months and clinical follow-up was scheduled regularly every 3 months. There were 46 patients of age 66 ± 12 years with male predominance (76%) recruited. Diagonal ostium (67%) was the most frequent target lesion site. The size and length of paclitaxel-eluting balloon and drug-eluting stent used in MV and SB were 3.01 ± 0.25 and 20 ± 4 mm, and 2.39 ± 0.25 and 17 ± 6 mm, respectively. Angiographic restudy was performed on 43 (93.5%) patients at 6.5 ± 1.6 months. The late loss in MV and SB were 0.04 ± 0.19 and 0.19 ± 0.32 mm, respectively. Angiographic restensosis was seen in 2 (4.7%) patients at SB, whereas no stenosis was induced in MV. Improvement of symptom was reported in 36 (78%) patients. At 1-year follow-up, no death, myocardial infarction, and stent thrombosis was observed; target vessel revascularization was performed on 3 (6.5%) patients. Treatment of isolated SB ostium stenosis using the shoulder technique is associated with a favorable short-term angiographic outcome. © 2017, Springer Japan.-
dc.languageeng-
dc.publisherSpringer Japan. The Journal's web site is located at www.springerlink.com/openurl.asp?genre=journal&issn=0910-8327-
dc.relation.ispartofHeart and Vessels-
dc.rightsThe final publication is available at Springer via http://dx.doi.org/[insert DOI]-
dc.subjectBifurcation stenosis-
dc.subjectDrug-eluting stent-
dc.subjectIsolated side branch ostium stenosis-
dc.subjectPaclitaxel-eluting balloon-
dc.subjectPercutaneous coronary intervention-
dc.subjectRestenosis-
dc.titleAngiographic study of the clinical liaison of drug-eluting stent and paclitaxel-eluting balloon in unifocal side branch ostium stenosis (ASCLEPIUS)-
dc.typeArticle-
dc.identifier.emailYiu, KH: khkyiu@hku.hk-
dc.identifier.authorityYiu, KH=rp01490-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00380-017-0970-y-
dc.identifier.pmid28357514-
dc.identifier.scopuseid_2-s2.0-85016410236-
dc.identifier.hkuros275231-
dc.identifier.volume32-
dc.identifier.issue9-
dc.identifier.spage1045-
dc.identifier.epage1050-
dc.identifier.isiWOS:000408369700001-
dc.publisher.placeJapan-

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