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Conference Paper: The Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus
Title | The Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus |
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Authors | |
Issue Date | 2016 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.valueinhealthjournal.com/ |
Citation | The 7th Asia-Pacific Conference of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR 2016), Singapore, 3-6 September 2016. In Value in Health, 2016, v. 19 n. 7, p. A811, abstract no. CE4 How to Cite? |
Abstract | OBJECTIVES: The Multidisciplinary Risk Assessment and Management Program –Diabetes Mellitus (RAMP-DM) was associated with reduction in diabetes-related complications. This study aimed to evaluate the short-term and lifetime cost-effectiveness of RAMP-DM from the public health provider’s perspective in Hong Kong. METHODS: An in-depth cost study was conducted to estimate the program cost. The short-term cost-effectiveness of RAMP-DM was evaluated using three-year observed events of diabetes-related complications, program cost and public health service utilization cost. A discrete event model was built to estimate the lifetime cost-effectiveness of RAMP-DM. The transition probabilities (TP) from no complication to diabetes-related complications and mortality were derived from a longitudinal 5-year cohort study on 128,309 DM patients and applied to the usual care group. The hazard ratios of developing complications were used to adjust the TP in RAMP-DM group. The RAMP-DM set-up costs were applied to the first year for the RAMP-DM group, and the ongoing costs were applied to lifetime model. The annual direct medical costs and utility scores for various diabetes-related complications referred to our previous studies in Chinese DM population. For short-term Incremental cost-effectiveness ratios were measured by dividing incremental cost of RAMP-DM accrued over incremental quality-adjusted life years gained from RAMP-DM. RESULTS: Over three–year period, the RAMP-DM group achieved clinical benefits of diabetes-related complications reduction in addition to a monetary saving in public health service utilization of US$2,703, resulting in a net saving of US$2,590 per subject after deduction of RAMP-DM program cost (US$113). Over lifetime, RAMP-DM was found to be cost-saving in terms of gaining 0.526 QALYs at a net saving of US$109 per subject over a lifetime. CONCLUSIONS: RAMP-DM was a cost-saving intervention in managing diabetic patients in short-term. Over lifetime, RAMP-DM was considered highly cost-effective benchmarked against a willingness-to-pay threshold of the annual GDP per capita in Hong Kong (US$38,123). |
Description | Conference Theme: Pharmacoeconomics and Outcomes Research in Asia-Pacific: Challenges, Opportunities, and Future Direction Research Podium Presentations - Session 2: no. CE4 |
Persistent Identifier | http://hdl.handle.net/10722/236380 |
ISSN | 2021 Impact Factor: 5.101 2020 SCImago Journal Rankings: 1.859 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Jiao, F | - |
dc.contributor.author | Lam, CLK | - |
dc.contributor.author | Fung, SCC | - |
dc.contributor.author | Wan, YF | - |
dc.contributor.author | Wong, CKH | - |
dc.contributor.author | McGhee, S | - |
dc.date.accessioned | 2016-11-25T00:52:33Z | - |
dc.date.available | 2016-11-25T00:52:33Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | The 7th Asia-Pacific Conference of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR 2016), Singapore, 3-6 September 2016. In Value in Health, 2016, v. 19 n. 7, p. A811, abstract no. CE4 | - |
dc.identifier.issn | 1098-3015 | - |
dc.identifier.uri | http://hdl.handle.net/10722/236380 | - |
dc.description | Conference Theme: Pharmacoeconomics and Outcomes Research in Asia-Pacific: Challenges, Opportunities, and Future Direction | - |
dc.description | Research Podium Presentations - Session 2: no. CE4 | - |
dc.description.abstract | OBJECTIVES: The Multidisciplinary Risk Assessment and Management Program –Diabetes Mellitus (RAMP-DM) was associated with reduction in diabetes-related complications. This study aimed to evaluate the short-term and lifetime cost-effectiveness of RAMP-DM from the public health provider’s perspective in Hong Kong. METHODS: An in-depth cost study was conducted to estimate the program cost. The short-term cost-effectiveness of RAMP-DM was evaluated using three-year observed events of diabetes-related complications, program cost and public health service utilization cost. A discrete event model was built to estimate the lifetime cost-effectiveness of RAMP-DM. The transition probabilities (TP) from no complication to diabetes-related complications and mortality were derived from a longitudinal 5-year cohort study on 128,309 DM patients and applied to the usual care group. The hazard ratios of developing complications were used to adjust the TP in RAMP-DM group. The RAMP-DM set-up costs were applied to the first year for the RAMP-DM group, and the ongoing costs were applied to lifetime model. The annual direct medical costs and utility scores for various diabetes-related complications referred to our previous studies in Chinese DM population. For short-term Incremental cost-effectiveness ratios were measured by dividing incremental cost of RAMP-DM accrued over incremental quality-adjusted life years gained from RAMP-DM. RESULTS: Over three–year period, the RAMP-DM group achieved clinical benefits of diabetes-related complications reduction in addition to a monetary saving in public health service utilization of US$2,703, resulting in a net saving of US$2,590 per subject after deduction of RAMP-DM program cost (US$113). Over lifetime, RAMP-DM was found to be cost-saving in terms of gaining 0.526 QALYs at a net saving of US$109 per subject over a lifetime. CONCLUSIONS: RAMP-DM was a cost-saving intervention in managing diabetic patients in short-term. Over lifetime, RAMP-DM was considered highly cost-effective benchmarked against a willingness-to-pay threshold of the annual GDP per capita in Hong Kong (US$38,123). | - |
dc.language | eng | - |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.valueinhealthjournal.com/ | - |
dc.relation.ispartof | Value in Health | - |
dc.title | The Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Lam, CLK: clklam@hku.hk | - |
dc.identifier.email | Fung, SCC: cfsc@hku.hk | - |
dc.identifier.email | Wan, YF: yfwan@hku.hk | - |
dc.identifier.email | Wong, CKH: carlosho@hku.hk | - |
dc.identifier.email | McGhee, S: smmcghee@hkucc.hku.hk | - |
dc.identifier.authority | Lam, CLK=rp00350 | - |
dc.identifier.authority | Fung, SCC=rp01330 | - |
dc.identifier.authority | Wong, CKH=rp01931 | - |
dc.identifier.authority | McGhee, S=rp00393 | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1016/j.jval.2016.08.707 | - |
dc.identifier.hkuros | 270590 | - |
dc.identifier.volume | 19 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | A811, abstract no. CE4 | - |
dc.identifier.epage | A811, abstract no. CE4 | - |
dc.identifier.isi | WOS:000396606302620 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1098-3015 | - |