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Conference Paper: The Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus

TitleThe Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus
Authors
Issue Date2016
PublisherElsevier Inc. The Journal's web site is located at http://www.valueinhealthjournal.com/
Citation
The 7th Asia-Pacific Conference of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR 2016), Singapore, 3-6 September 2016. In Value in Health, 2016, v. 19 n. 7, p. A811, abstract no. CE4 How to Cite?
AbstractOBJECTIVES: The Multidisciplinary Risk Assessment and Management Program –Diabetes Mellitus (RAMP-DM) was associated with reduction in diabetes-related complications. This study aimed to evaluate the short-term and lifetime cost-effectiveness of RAMP-DM from the public health provider’s perspective in Hong Kong. METHODS: An in-depth cost study was conducted to estimate the program cost. The short-term cost-effectiveness of RAMP-DM was evaluated using three-year observed events of diabetes-related complications, program cost and public health service utilization cost. A discrete event model was built to estimate the lifetime cost-effectiveness of RAMP-DM. The transition probabilities (TP) from no complication to diabetes-related complications and mortality were derived from a longitudinal 5-year cohort study on 128,309 DM patients and applied to the usual care group. The hazard ratios of developing complications were used to adjust the TP in RAMP-DM group. The RAMP-DM set-up costs were applied to the first year for the RAMP-DM group, and the ongoing costs were applied to lifetime model. The annual direct medical costs and utility scores for various diabetes-related complications referred to our previous studies in Chinese DM population. For short-term Incremental cost-effectiveness ratios were measured by dividing incremental cost of RAMP-DM accrued over incremental quality-adjusted life years gained from RAMP-DM. RESULTS: Over three–year period, the RAMP-DM group achieved clinical benefits of diabetes-related complications reduction in addition to a monetary saving in public health service utilization of US$2,703, resulting in a net saving of US$2,590 per subject after deduction of RAMP-DM program cost (US$113). Over lifetime, RAMP-DM was found to be cost-saving in terms of gaining 0.526 QALYs at a net saving of US$109 per subject over a lifetime. CONCLUSIONS: RAMP-DM was a cost-saving intervention in managing diabetic patients in short-term. Over lifetime, RAMP-DM was considered highly cost-effective benchmarked against a willingness-to-pay threshold of the annual GDP per capita in Hong Kong (US$38,123).
DescriptionConference Theme: Pharmacoeconomics and Outcomes Research in Asia-Pacific: Challenges, Opportunities, and Future Direction
Research Podium Presentations - Session 2: no. CE4
Persistent Identifierhttp://hdl.handle.net/10722/236380
ISSN
2021 Impact Factor: 5.101
2020 SCImago Journal Rankings: 1.859
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJiao, F-
dc.contributor.authorLam, CLK-
dc.contributor.authorFung, SCC-
dc.contributor.authorWan, YF-
dc.contributor.authorWong, CKH-
dc.contributor.authorMcGhee, S-
dc.date.accessioned2016-11-25T00:52:33Z-
dc.date.available2016-11-25T00:52:33Z-
dc.date.issued2016-
dc.identifier.citationThe 7th Asia-Pacific Conference of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR 2016), Singapore, 3-6 September 2016. In Value in Health, 2016, v. 19 n. 7, p. A811, abstract no. CE4-
dc.identifier.issn1098-3015-
dc.identifier.urihttp://hdl.handle.net/10722/236380-
dc.descriptionConference Theme: Pharmacoeconomics and Outcomes Research in Asia-Pacific: Challenges, Opportunities, and Future Direction-
dc.descriptionResearch Podium Presentations - Session 2: no. CE4-
dc.description.abstractOBJECTIVES: The Multidisciplinary Risk Assessment and Management Program –Diabetes Mellitus (RAMP-DM) was associated with reduction in diabetes-related complications. This study aimed to evaluate the short-term and lifetime cost-effectiveness of RAMP-DM from the public health provider’s perspective in Hong Kong. METHODS: An in-depth cost study was conducted to estimate the program cost. The short-term cost-effectiveness of RAMP-DM was evaluated using three-year observed events of diabetes-related complications, program cost and public health service utilization cost. A discrete event model was built to estimate the lifetime cost-effectiveness of RAMP-DM. The transition probabilities (TP) from no complication to diabetes-related complications and mortality were derived from a longitudinal 5-year cohort study on 128,309 DM patients and applied to the usual care group. The hazard ratios of developing complications were used to adjust the TP in RAMP-DM group. The RAMP-DM set-up costs were applied to the first year for the RAMP-DM group, and the ongoing costs were applied to lifetime model. The annual direct medical costs and utility scores for various diabetes-related complications referred to our previous studies in Chinese DM population. For short-term Incremental cost-effectiveness ratios were measured by dividing incremental cost of RAMP-DM accrued over incremental quality-adjusted life years gained from RAMP-DM. RESULTS: Over three–year period, the RAMP-DM group achieved clinical benefits of diabetes-related complications reduction in addition to a monetary saving in public health service utilization of US$2,703, resulting in a net saving of US$2,590 per subject after deduction of RAMP-DM program cost (US$113). Over lifetime, RAMP-DM was found to be cost-saving in terms of gaining 0.526 QALYs at a net saving of US$109 per subject over a lifetime. CONCLUSIONS: RAMP-DM was a cost-saving intervention in managing diabetic patients in short-term. Over lifetime, RAMP-DM was considered highly cost-effective benchmarked against a willingness-to-pay threshold of the annual GDP per capita in Hong Kong (US$38,123).-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.valueinhealthjournal.com/-
dc.relation.ispartofValue in Health-
dc.titleThe Multidisciplinary Risk Assessment and Management Program - diabetes mellitus (RAMP-DM) was cost-effective for managing patients with diabetes mellitus-
dc.typeConference_Paper-
dc.identifier.emailLam, CLK: clklam@hku.hk-
dc.identifier.emailFung, SCC: cfsc@hku.hk-
dc.identifier.emailWan, YF: yfwan@hku.hk-
dc.identifier.emailWong, CKH: carlosho@hku.hk-
dc.identifier.emailMcGhee, S: smmcghee@hkucc.hku.hk-
dc.identifier.authorityLam, CLK=rp00350-
dc.identifier.authorityFung, SCC=rp01330-
dc.identifier.authorityWong, CKH=rp01931-
dc.identifier.authorityMcGhee, S=rp00393-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1016/j.jval.2016.08.707-
dc.identifier.hkuros270590-
dc.identifier.volume19-
dc.identifier.issue7-
dc.identifier.spageA811, abstract no. CE4-
dc.identifier.epageA811, abstract no. CE4-
dc.identifier.isiWOS:000396606302620-
dc.publisher.placeUnited States-
dc.identifier.issnl1098-3015-

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