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Conference Paper: Analysis of three pre-operative risk assessment tools for prostate cancer in a local Chinese cohort undergoing radical prostatectomy

TitleAnalysis of three pre-operative risk assessment tools for prostate cancer in a local Chinese cohort undergoing radical prostatectomy
Authors
Issue Date2016
PublisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/IJU
Citation
The 14th Urological Association of Asia Congress (UAA 2016) in conjunction with UROFAIR 2016, Urology Residents' Course 2016, and the 30th Anniversary of the Singapore Urological Association, Singapore, 20-24 July 2016. In International Journal of Urology, 2016, v. 23 suppl. S1, p. 62, abstract no. C-OPRO-1860 How to Cite?
AbstractOBJECTIVES: To compare the performance of the CAPRA score, Kattan nomogram and Stephenson nomogram in a local Chinese cohort of patients with prostate cancer undergoing radical prostatectomy. METHODS: This is a review of a prospective cohort of men who underwent radical prostatectomy for prostate cancer. CAPRA score, Kattan score and Stephenson score were calculated by analysis of variables for predicting biochemical recurrence. Biochemical recurrence was defined as PSA more than 0.2 ng/mL or secondary treatment for a rising PSA. Performance of the three risk assessment tools was evaluated using Harrell’s concordance index, plotting calibration curves, and constructing decision analysis curves. RESULTS: Two hundred and eighty-seven men who underwent radical prostatectomy from 1998 to 2012 were recruited. Concordance index for the three assessment tools were high (0.69 for CAPRA score, 0.71 for Kattan score, 0.73 for Stephenson score). The Stephenson score had the best calibration plot in predicting biochemical free recurrence probability. The Stephenson score also had a better performance across various threshold probability in the decision curve analysis. CONCLUSIONS: All three assessment tools were validated in our local Chinese cohort. Stephenson score had the best performance in predicting biochemical free recurrence probability and in the decision curve analysis.
DescriptionConference Theme: Urological Advancement in Asia
Abstract and Poster Presentation
This free journal suppl. entitled: Special Issue: 14th Urological Association of Asia Congress 2016 Singapore
Persistent Identifierhttp://hdl.handle.net/10722/235197
ISSN
2015 Impact Factor: 1.878
2015 SCImago Journal Rankings: 0.841

 

DC FieldValueLanguage
dc.contributor.authorTsang, CF-
dc.contributor.authorYiu, MK-
dc.contributor.authorHo, SHB-
dc.contributor.authorNg, ATL-
dc.contributor.authorWong, JKW-
dc.contributor.authorWong, CKW-
dc.contributor.authorMa, WK-
dc.contributor.authorTsu, HLJ-
dc.date.accessioned2016-10-14T13:51:52Z-
dc.date.available2016-10-14T13:51:52Z-
dc.date.issued2016-
dc.identifier.citationThe 14th Urological Association of Asia Congress (UAA 2016) in conjunction with UROFAIR 2016, Urology Residents' Course 2016, and the 30th Anniversary of the Singapore Urological Association, Singapore, 20-24 July 2016. In International Journal of Urology, 2016, v. 23 suppl. S1, p. 62, abstract no. C-OPRO-1860-
dc.identifier.issn0919-8172-
dc.identifier.urihttp://hdl.handle.net/10722/235197-
dc.descriptionConference Theme: Urological Advancement in Asia-
dc.descriptionAbstract and Poster Presentation-
dc.descriptionThis free journal suppl. entitled: Special Issue: 14th Urological Association of Asia Congress 2016 Singapore-
dc.description.abstractOBJECTIVES: To compare the performance of the CAPRA score, Kattan nomogram and Stephenson nomogram in a local Chinese cohort of patients with prostate cancer undergoing radical prostatectomy. METHODS: This is a review of a prospective cohort of men who underwent radical prostatectomy for prostate cancer. CAPRA score, Kattan score and Stephenson score were calculated by analysis of variables for predicting biochemical recurrence. Biochemical recurrence was defined as PSA more than 0.2 ng/mL or secondary treatment for a rising PSA. Performance of the three risk assessment tools was evaluated using Harrell’s concordance index, plotting calibration curves, and constructing decision analysis curves. RESULTS: Two hundred and eighty-seven men who underwent radical prostatectomy from 1998 to 2012 were recruited. Concordance index for the three assessment tools were high (0.69 for CAPRA score, 0.71 for Kattan score, 0.73 for Stephenson score). The Stephenson score had the best calibration plot in predicting biochemical free recurrence probability. The Stephenson score also had a better performance across various threshold probability in the decision curve analysis. CONCLUSIONS: All three assessment tools were validated in our local Chinese cohort. Stephenson score had the best performance in predicting biochemical free recurrence probability and in the decision curve analysis.-
dc.languageeng-
dc.publisherBlackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/IJU-
dc.relation.ispartofInternational Journal of Urology-
dc.rightsThe definitive version is available at www.blackwell-synergy.com-
dc.titleAnalysis of three pre-operative risk assessment tools for prostate cancer in a local Chinese cohort undergoing radical prostatectomy-
dc.typeConference_Paper-
dc.identifier.emailYiu, MK: pmkyiu@hku.hk-
dc.identifier.emailWong, CKW: kwwongab@hku.hk-
dc.identifier.emailMa, WK: mwk054@hku.hk-
dc.identifier.emailTsu, HLJ: jamestsu@hku.hk-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/iju.13149-
dc.identifier.hkuros270379-
dc.identifier.volume23-
dc.identifier.issuesuppl. S1-
dc.identifier.spage62, abstract no. C-OPRO-1860-
dc.identifier.epage62, abstract no. C-OPRO-1860-
dc.publisher.placeAustralia-

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