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Article: Biological Applications of a Nanomanipulator Based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level.

TitleBiological Applications of a Nanomanipulator Based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level.
Authors
Issue Date2015
Citation
IEEE Nanotechnology Magazine, 2015, v. 9, p. 25-35 How to Cite?
AbstractCells are the structural and functional unit of living organisms. Knowledge of cellular behaviors is critical for us to understand the underlying mechanisms that guide the physiological and pathological changes in living organisms. So far, virtually all knowledge of the molecular reactions in cells has come from the ensemble measurements done in test tubes with purified molecules [1], [2]. The disadvantage of this approach is that experiments with purified molecules require the lysis of cells, meaning that the obtained results may not reflect the real situations of living cells.
Persistent Identifierhttp://hdl.handle.net/10722/234606

 

DC FieldValueLanguage
dc.contributor.authorLI, M-
dc.contributor.authorLIU, L-
dc.contributor.authorXi, N-
dc.contributor.authorWANG, Y-
dc.date.accessioned2016-10-14T13:48:00Z-
dc.date.available2016-10-14T13:48:00Z-
dc.date.issued2015-
dc.identifier.citationIEEE Nanotechnology Magazine, 2015, v. 9, p. 25-35-
dc.identifier.urihttp://hdl.handle.net/10722/234606-
dc.description.abstractCells are the structural and functional unit of living organisms. Knowledge of cellular behaviors is critical for us to understand the underlying mechanisms that guide the physiological and pathological changes in living organisms. So far, virtually all knowledge of the molecular reactions in cells has come from the ensemble measurements done in test tubes with purified molecules [1], [2]. The disadvantage of this approach is that experiments with purified molecules require the lysis of cells, meaning that the obtained results may not reflect the real situations of living cells.-
dc.languageeng-
dc.relation.ispartofIEEE Nanotechnology Magazine-
dc.titleBiological Applications of a Nanomanipulator Based on AFM: In situ visualization and quantification of cellular behaviors at the single-molecule level.-
dc.typeArticle-
dc.identifier.emailXi, N: xining@hku.hk-
dc.identifier.authorityXi, N=rp02044-
dc.identifier.doi10.1109/MNANO.2015.2441110-
dc.identifier.hkuros269328-
dc.identifier.volume9-
dc.identifier.spage25-
dc.identifier.epage35-
dc.publisher.placeIEEE Xplore-

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