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Conference Paper: Relationships between salivary cortisol, symptom severity and lifestyle factors in chronic schizophrenic patients

TitleRelationships between salivary cortisol, symptom severity and lifestyle factors in chronic schizophrenic patients
Authors
Issue Date2016
PublisherSpringer New York LLC. The Journal's web site is located at http://www.springer.com/medicine/journal/12160
Citation
The 37th Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine (SBM 2016), Washington, DC., 30 March-2 April 2016. In Annals of Behavioral Medicine, 2016, v. 50 suppl. 1, p. S310, abstract no. D091 How to Cite?
AbstractBACKGROUND: This study examined the relationships between diurnal cortisol patterns and perceived stress, physical activity, symptom severity, and daily functioning in patients with chronic schizophrenia. METHODS: The participants were 149 Chinese patients with chronic schizophrenia. Diagnostic assessments of body-mass index (BMI), psychotic symptoms and neurological deficits were made, and self-reported measures of physical activity, perceived stress, and daily functioning were recorded. Diurnal cortisol slope was derived from the salivary cortisol measures collected upon waking, 30 min after waking, before lunch, and before bedtime. A path modeling analysis was performed to investigate the relationships of the diurnal cortisol slope and its antecedents and outcomes. RESULTS: Higher levels of perceived stress, higher BMI, and less physical activity predicted lower waking cortisol and flattened diurnal cortisol slopes. Controlling for age and gender, flattened diurnal cortisol slopes were significantly associated with higher levels of depressive symptoms, cognitive symptoms, motor deficit, and poorer daily functioning. DISCUSSIONS: The results support the neural diathesis–stress model and highlight the importance of the hypothalamic–pituitary–adrenal axis in mediating the effects of stress and symptom severity among patients with chronic schizophrenia. The practical implications of the findings are discussed. LEARNING OBJECTIVES: 1. Communicate the neural diathesis–stress model and highlight the importance of the hypothalamic–pituitary–adrenal axis 2. Describe the associations between lifestyle factors and diurnal cortisol patterns in schizophrenic patients
Persistent Identifierhttp://hdl.handle.net/10722/233192
ISSN
2015 Impact Factor: 4.195
2015 SCImago Journal Rankings: 2.112

 

DC FieldValueLanguage
dc.contributor.authorHo, RTH-
dc.contributor.authorFong, TCT-
dc.contributor.authorWan, HYA-
dc.contributor.authorAu Yeung, FSW-
dc.date.accessioned2016-09-20T05:35:11Z-
dc.date.available2016-09-20T05:35:11Z-
dc.date.issued2016-
dc.identifier.citationThe 37th Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine (SBM 2016), Washington, DC., 30 March-2 April 2016. In Annals of Behavioral Medicine, 2016, v. 50 suppl. 1, p. S310, abstract no. D091-
dc.identifier.issn0883-6612-
dc.identifier.urihttp://hdl.handle.net/10722/233192-
dc.description.abstractBACKGROUND: This study examined the relationships between diurnal cortisol patterns and perceived stress, physical activity, symptom severity, and daily functioning in patients with chronic schizophrenia. METHODS: The participants were 149 Chinese patients with chronic schizophrenia. Diagnostic assessments of body-mass index (BMI), psychotic symptoms and neurological deficits were made, and self-reported measures of physical activity, perceived stress, and daily functioning were recorded. Diurnal cortisol slope was derived from the salivary cortisol measures collected upon waking, 30 min after waking, before lunch, and before bedtime. A path modeling analysis was performed to investigate the relationships of the diurnal cortisol slope and its antecedents and outcomes. RESULTS: Higher levels of perceived stress, higher BMI, and less physical activity predicted lower waking cortisol and flattened diurnal cortisol slopes. Controlling for age and gender, flattened diurnal cortisol slopes were significantly associated with higher levels of depressive symptoms, cognitive symptoms, motor deficit, and poorer daily functioning. DISCUSSIONS: The results support the neural diathesis–stress model and highlight the importance of the hypothalamic–pituitary–adrenal axis in mediating the effects of stress and symptom severity among patients with chronic schizophrenia. The practical implications of the findings are discussed. LEARNING OBJECTIVES: 1. Communicate the neural diathesis–stress model and highlight the importance of the hypothalamic–pituitary–adrenal axis 2. Describe the associations between lifestyle factors and diurnal cortisol patterns in schizophrenic patients-
dc.languageeng-
dc.publisherSpringer New York LLC. The Journal's web site is located at http://www.springer.com/medicine/journal/12160-
dc.relation.ispartofAnnals of Behavioral Medicine-
dc.rightsThe final publication is available at Springer via http://dx.doi.org/[insert DOI]-
dc.titleRelationships between salivary cortisol, symptom severity and lifestyle factors in chronic schizophrenic patients-
dc.typeConference_Paper-
dc.identifier.emailHo, RTH: tinho@hku.hk-
dc.identifier.emailFong, TCT: ttaatt@hku.hk-
dc.identifier.emailWan, HYA: awan@hku.hk-
dc.identifier.authorityHo, RTH=rp00497-
dc.identifier.doi10.1007/s12160-015-9766-4-
dc.identifier.hkuros263156-
dc.identifier.volume50-
dc.identifier.issuesuppl. 1-
dc.identifier.spageS310, abstract no. D091-
dc.identifier.epageS310, abstract no. D091-
dc.publisher.placeUnited States-

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