File Download
  Links for fulltext
     (May Require Subscription)

Conference Paper: Incidence and medical resource utilization for cardiovascular events in Asia

TitleIncidence and medical resource utilization for cardiovascular events in Asia
Authors
Issue Date2016
PublisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/5669
Citation
The 32nd International Conference on Pharmacoepidemiology and Therapeutic Risk Management, Dublin, Ireland, 25-28 August 2016, In Pharmacoepidemiology and Drug Safety, 2016, v. 25 suppl. S3, p. 285-286, abstract no. 488 How to Cite?
AbstractBACKGROUND: Cardiovascular events are the leading cause of mortality and morbidity in United States (US) and other industrialized countries. However, little is known about trends in the incidence and resource utilization of these conditions in Asia as life-style have westernized. OBJECTIVES: To describe the incidence (IR) and medical resource utilization of cardiovascular events among the study population in Hong Kong (HK), Taiwan (TW), Japan (JP) and US from 2006-2013. METHODS: We utilized the OMOP common data model in the AsPEN converted from a 1% random sample of Hong Kong Clinical Data Analysis and Reporting System (CDARS), a 5% random sample from Taiwan National Health Insurance Research Database (NHIRD), Japan Medical Data Center Database (JMDC), and 5% sample from the US Medicare database. Hospitalization and length of hospital stay for myocardial infarction (MI) or acute coronary syndrome (ACS) were identified from the databases. Comorbidities and concurrent medications for the patients at the time of the MI/ACS were assessed. RESULTS: The age-gender adjusted IR (per 100 persons) for MI/ACS were 0.2 in HK, 0.1 in JP and TW, and 0.9 in US. Average number of hospitalizations increased from 4.7-15.2 in HK, 0.8-1.1 in JP, 4.5-7.0 in US but slightly decreased in TW (10.8-10.0) over the study period. Average length of stay was increased by 14.5%-107.9% across the four countries. Congestive heart failure and hypertension were the most common comorbidities in these patients. Medications used after MI/ACS were quite different across sites: 93% of HK and 63% of TW patients started antiplatelet after MI/ACS vs. only 14% patients in JP and 0.1% in US. 61% patients in HK started renin-angiotensin system (RAS) inhibitors after diagnosis, whereas 22.1% and 38.3% patients in TW and US started the same treatment. CONCLUSIONS: The IR of MI/ACS were similar among different Asian sites but were higher in US. An increasing number of hospitalizations and length of stay suggested an increasing disease burden. Discrepancy in recommended drug use after MI/ACS provides additional insights into the variation across countries in treatment patterns that must be appreciated when undertaking multinational studies.
DescriptionThis free journal suppl. entitled: Abstracts of the 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management ... Dublin, Ireland August 25–28, 2016
Persistent Identifierhttp://hdl.handle.net/10722/232557
ISSN
2015 Impact Factor: 2.908
2015 SCImago Journal Rankings: 1.804

 

DC FieldValueLanguage
dc.contributor.authorMan, KCK-
dc.contributor.authorLai, EC-
dc.contributor.authorSu, CC-
dc.contributor.authorKubota, K-
dc.contributor.authorKimura, S-
dc.contributor.authorStang, P-
dc.contributor.authorSchuemie, M-
dc.contributor.authorRyan, P-
dc.contributor.authorKao Yang, YH-
dc.contributor.authorZhang, Y-
dc.contributor.authorSetoguchi, S-
dc.contributor.authorWong, ICK-
dc.date.accessioned2016-09-20T05:30:51Z-
dc.date.available2016-09-20T05:30:51Z-
dc.date.issued2016-
dc.identifier.citationThe 32nd International Conference on Pharmacoepidemiology and Therapeutic Risk Management, Dublin, Ireland, 25-28 August 2016, In Pharmacoepidemiology and Drug Safety, 2016, v. 25 suppl. S3, p. 285-286, abstract no. 488-
dc.identifier.issn1053-8569-
dc.identifier.urihttp://hdl.handle.net/10722/232557-
dc.descriptionThis free journal suppl. entitled: Abstracts of the 32nd International Conference on Pharmacoepidemiology & Therapeutic Risk Management ... Dublin, Ireland August 25–28, 2016-
dc.description.abstractBACKGROUND: Cardiovascular events are the leading cause of mortality and morbidity in United States (US) and other industrialized countries. However, little is known about trends in the incidence and resource utilization of these conditions in Asia as life-style have westernized. OBJECTIVES: To describe the incidence (IR) and medical resource utilization of cardiovascular events among the study population in Hong Kong (HK), Taiwan (TW), Japan (JP) and US from 2006-2013. METHODS: We utilized the OMOP common data model in the AsPEN converted from a 1% random sample of Hong Kong Clinical Data Analysis and Reporting System (CDARS), a 5% random sample from Taiwan National Health Insurance Research Database (NHIRD), Japan Medical Data Center Database (JMDC), and 5% sample from the US Medicare database. Hospitalization and length of hospital stay for myocardial infarction (MI) or acute coronary syndrome (ACS) were identified from the databases. Comorbidities and concurrent medications for the patients at the time of the MI/ACS were assessed. RESULTS: The age-gender adjusted IR (per 100 persons) for MI/ACS were 0.2 in HK, 0.1 in JP and TW, and 0.9 in US. Average number of hospitalizations increased from 4.7-15.2 in HK, 0.8-1.1 in JP, 4.5-7.0 in US but slightly decreased in TW (10.8-10.0) over the study period. Average length of stay was increased by 14.5%-107.9% across the four countries. Congestive heart failure and hypertension were the most common comorbidities in these patients. Medications used after MI/ACS were quite different across sites: 93% of HK and 63% of TW patients started antiplatelet after MI/ACS vs. only 14% patients in JP and 0.1% in US. 61% patients in HK started renin-angiotensin system (RAS) inhibitors after diagnosis, whereas 22.1% and 38.3% patients in TW and US started the same treatment. CONCLUSIONS: The IR of MI/ACS were similar among different Asian sites but were higher in US. An increasing number of hospitalizations and length of stay suggested an increasing disease burden. Discrepancy in recommended drug use after MI/ACS provides additional insights into the variation across countries in treatment patterns that must be appreciated when undertaking multinational studies.-
dc.languageeng-
dc.publisherJohn Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/5669-
dc.relation.ispartofPharmacoepidemiology and Drug Safety-
dc.rightsPharmacoepidemiology and Drug Safety. Copyright © John Wiley & Sons Ltd.-
dc.titleIncidence and medical resource utilization for cardiovascular events in Asia-
dc.typeConference_Paper-
dc.identifier.emailMan, KCK: mkckth@hku.hk-
dc.identifier.emailWong, ICK: wongick@hku.hk-
dc.identifier.authorityWong, ICK=rp01480-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1002/pds.4070-
dc.identifier.hkuros266638-
dc.identifier.volume25-
dc.identifier.issuesuppl. S3-
dc.identifier.spage285, abstract no. 488-
dc.identifier.epage286-
dc.publisher.placeUnited Kingdom-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats