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Article: Nano-Engineered Environment for Nerve Regeneration: Scaffolds, Functional Molecules and Stem Cells

TitleNano-Engineered Environment for Nerve Regeneration: Scaffolds, Functional Molecules and Stem Cells
Authors
Issue Date2016
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cscrt/index.htm
Citation
Current Stem Cell Research & Therapy, 2016, v. 11 n. 8, p. 605 - 617 How to Cite?
AbstractOne of the most complex systems in the human body is the nervous system, which is divided into the central and peripheral nervous systems. The regeneration of the CNS is a complex and challenging biological phenomenon hindered by the low regenerative capacity of neurons and the prohibition factors in response to nerve injuries. To date, no effective approach can achieve complete recovery and fully restore the functions of the nervous system once it has been damaged. Developments in neuroscience have identified properties of the local environment with a critical role in nerve regeneration. Advances in biomaterials and biomedical engineering have explored new approaches of constructing permissive environments for nerve regeneration, thereby enabling optimism with regard to nerve-injury treatment. This article reviews recent progress in nanoengineered environments for aiding nerve-injury repair and regeneration, including nanofibrous scaffolds, functional molecules, and stem cells.
Persistent Identifierhttp://hdl.handle.net/10722/230585
ISSN
2015 Impact Factor: 2.645
2015 SCImago Journal Rankings: 0.869

 

DC FieldValueLanguage
dc.contributor.authorHe, L-
dc.contributor.authorTian, L-
dc.contributor.authorSun, Y-
dc.contributor.authorZhang, Y-
dc.contributor.authorXue, W-
dc.contributor.authorSo, KF-
dc.contributor.authorRamakrishna, S-
dc.contributor.authorWu, W-
dc.date.accessioned2016-08-23T14:17:54Z-
dc.date.available2016-08-23T14:17:54Z-
dc.date.issued2016-
dc.identifier.citationCurrent Stem Cell Research & Therapy, 2016, v. 11 n. 8, p. 605 - 617-
dc.identifier.issn1574-888X-
dc.identifier.urihttp://hdl.handle.net/10722/230585-
dc.description.abstractOne of the most complex systems in the human body is the nervous system, which is divided into the central and peripheral nervous systems. The regeneration of the CNS is a complex and challenging biological phenomenon hindered by the low regenerative capacity of neurons and the prohibition factors in response to nerve injuries. To date, no effective approach can achieve complete recovery and fully restore the functions of the nervous system once it has been damaged. Developments in neuroscience have identified properties of the local environment with a critical role in nerve regeneration. Advances in biomaterials and biomedical engineering have explored new approaches of constructing permissive environments for nerve regeneration, thereby enabling optimism with regard to nerve-injury treatment. This article reviews recent progress in nanoengineered environments for aiding nerve-injury repair and regeneration, including nanofibrous scaffolds, functional molecules, and stem cells.-
dc.languageeng-
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cscrt/index.htm-
dc.relation.ispartofCurrent Stem Cell Research & Therapy-
dc.titleNano-Engineered Environment for Nerve Regeneration: Scaffolds, Functional Molecules and Stem Cells-
dc.typeArticle-
dc.identifier.emailSo, KF: hrmaskf@hku.hk-
dc.identifier.emailWu, W: wtwu@hkucc.hku.hk-
dc.identifier.authoritySo, KF=rp00329-
dc.identifier.authorityWu, W=rp00419-
dc.identifier.doi10.2174/1574888X10666151001114735-
dc.identifier.pmid26423299-
dc.identifier.hkuros262998-
dc.identifier.volume11-
dc.identifier.issue8-
dc.identifier.spage605-
dc.identifier.epage617-
dc.publisher.placeNetherlands-

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