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Conference Paper: Concentration-dependent vascular effects of divalent manganese

TitleConcentration-dependent vascular effects of divalent manganese
Authors
Issue Date2015
PublisherMedcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3
Citation
The 19th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine held in conjunction with the 10th Across the Strait Scientific Conference on Cardiovascular Science, Hong Kong, 21 November 2015. In Journal of the Hong Kong College of Cardiology, 2015, v. 23 n. 2, p. 92, abstract no. OP9 How to Cite?
AbstractOBJECTIVES: Divalent manganese is a cofactor for soluble guanylyl cyclase (sGC), the enzyme producing cyclic GMP in vascular smooth muscle cells that causes relaxation. Manganese competes with magnesium to activate sGC. These divalent cations can bias the activity of the enzyme to produce cyclic nucleotides other than cyclic GMP, in particular cyclic AMP and cyclic IMP. Cyclic IMP, preferably produced in the presence of magnesium, can cause contraction in ...
DescriptionOral Presentation: no. OP9
Persistent Identifierhttp://hdl.handle.net/10722/229985
ISSN
2015 SCImago Journal Rankings: 0.102

 

DC FieldValueLanguage
dc.contributor.authorDetremmerie, CMS-
dc.contributor.authorLeung, SWS-
dc.contributor.authorVanhoutte, PM-
dc.date.accessioned2016-08-23T14:14:28Z-
dc.date.available2016-08-23T14:14:28Z-
dc.date.issued2015-
dc.identifier.citationThe 19th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine held in conjunction with the 10th Across the Strait Scientific Conference on Cardiovascular Science, Hong Kong, 21 November 2015. In Journal of the Hong Kong College of Cardiology, 2015, v. 23 n. 2, p. 92, abstract no. OP9-
dc.identifier.issn1027-7811-
dc.identifier.urihttp://hdl.handle.net/10722/229985-
dc.descriptionOral Presentation: no. OP9-
dc.description.abstractOBJECTIVES: Divalent manganese is a cofactor for soluble guanylyl cyclase (sGC), the enzyme producing cyclic GMP in vascular smooth muscle cells that causes relaxation. Manganese competes with magnesium to activate sGC. These divalent cations can bias the activity of the enzyme to produce cyclic nucleotides other than cyclic GMP, in particular cyclic AMP and cyclic IMP. Cyclic IMP, preferably produced in the presence of magnesium, can cause contraction in ...-
dc.languageeng-
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3-
dc.relation.ispartofJournal of the Hong Kong College of Cardiology-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleConcentration-dependent vascular effects of divalent manganese-
dc.typeConference_Paper-
dc.identifier.emailLeung, SWS: swsleung@hku.hk-
dc.identifier.emailVanhoutte, PM: vanhoutt@hku.hk-
dc.identifier.authorityLeung, SWS=rp00235-
dc.identifier.authorityVanhoutte, PM=rp00238-
dc.description.naturepostprint-
dc.identifier.hkuros262190-
dc.identifier.volume23-
dc.identifier.issue2-
dc.identifier.spage92, abstract no. OP9-
dc.identifier.epage92, abstract no. OP9-
dc.publisher.placeHong Kong-

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