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Article: The Diagnostic Utility of Cardiac Biomarkers in Dialysis Patients

TitleThe Diagnostic Utility of Cardiac Biomarkers in Dialysis Patients
Authors
Issue Date2012
Citation
Seminars in Dialysis, 2012, v. 25, n. 4, p. 388-396 How to Cite?
AbstractMortality in dialysis patients remains high due to excessive cardiovascular disease burden from coronary artery disease, left ventricular hypertrophy, and heart failure. Thus, cardiovascular risk stratification is an important aspect in managing dialysis patients; it may enable early identification of high-risk patients to optimize therapeutic interventions that may ultimately lower their cardiovascular morbidity and mortality. In particular, serum cardiac biomarkers that are readily measured, inexpensive, reproducible with high sensitivity and specificity, may have potential for cardiovascular risk prediction and stratification. Cardiac troponin represents a highly sensitive and specific marker of myocardial damage and is a current gold standard test for diagnosing acute myocardial infarction in the general population. On the other hand, natriuretic peptides, released from the heart secondary to increased left ventricular wall stress, have emerged as a diagnostic marker for heart failure in the general population. These two biomarkers reflect unique pathology of the myocardium and are powerful prognostic markers in the dialysis population. This article reviews the diagnostic potentials of these two cardiac biomarkers and their clinical application in the dialysis population. © 2012 Wiley Periodicals, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/228468
ISSN
2015 Impact Factor: 1.912
2015 SCImago Journal Rankings: 0.739

 

DC FieldValueLanguage
dc.contributor.authorWang, Angela Yee Moon-
dc.contributor.authorWai-Kei Lam, Christopher-
dc.date.accessioned2016-08-13T08:02:29Z-
dc.date.available2016-08-13T08:02:29Z-
dc.date.issued2012-
dc.identifier.citationSeminars in Dialysis, 2012, v. 25, n. 4, p. 388-396-
dc.identifier.issn0894-0959-
dc.identifier.urihttp://hdl.handle.net/10722/228468-
dc.description.abstractMortality in dialysis patients remains high due to excessive cardiovascular disease burden from coronary artery disease, left ventricular hypertrophy, and heart failure. Thus, cardiovascular risk stratification is an important aspect in managing dialysis patients; it may enable early identification of high-risk patients to optimize therapeutic interventions that may ultimately lower their cardiovascular morbidity and mortality. In particular, serum cardiac biomarkers that are readily measured, inexpensive, reproducible with high sensitivity and specificity, may have potential for cardiovascular risk prediction and stratification. Cardiac troponin represents a highly sensitive and specific marker of myocardial damage and is a current gold standard test for diagnosing acute myocardial infarction in the general population. On the other hand, natriuretic peptides, released from the heart secondary to increased left ventricular wall stress, have emerged as a diagnostic marker for heart failure in the general population. These two biomarkers reflect unique pathology of the myocardium and are powerful prognostic markers in the dialysis population. This article reviews the diagnostic potentials of these two cardiac biomarkers and their clinical application in the dialysis population. © 2012 Wiley Periodicals, Inc.-
dc.languageeng-
dc.relation.ispartofSeminars in Dialysis-
dc.titleThe Diagnostic Utility of Cardiac Biomarkers in Dialysis Patients-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1525-139X.2012.01099.x-
dc.identifier.pmid22748194-
dc.identifier.scopuseid_2-s2.0-84864021944-
dc.identifier.volume25-
dc.identifier.issue4-
dc.identifier.spage388-
dc.identifier.epage396-
dc.identifier.eissn1525-139X-

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