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Article: Cutaneous Adverse Effects of Lithium: Epidemiology and Management

TitleCutaneous Adverse Effects of Lithium: Epidemiology and Management
Authors
Issue Date2004
PublisherAdis International Ltd. The Journal's web site is located at http://dermatology.adisonline.com/
Citation
American Journal of Clinical Dermatology, 2004, v. 5 n. 1, p. 3-8 How to Cite?
AbstractAcneiform eruption, psoriasis, folliculitis, and maculopapular eruption have been described as adverse reactions to lithium therapy. In controlled studies, patients treated with lithium developed more cutaneous reactions, particularly acne and psoriasis, than patients receiving other psychotropics, with a prevalence in lithium-treated patients as high as 45%. Male patients taking lithium are more susceptible to developing cutaneous reactions than their female counterparts. Lithium tends to worsen or precipitate cutaneous conditions that are characterized by the pathological findings of neutrophilic infiltration. As lithium-related cutaneous adverse effects can be distressing to patients and may affect medication compliance, attention should be paid to skin problems in patients receiving lithium therapy. Management without cessation of lithium therapy is usually feasible except in some patients with psoriasis that is resistant to treatment. Paradoxically, therapeutic effects of topically applied lithium have been noted in seborrheic dermatitis and recurrent herpes infections.
Persistent Identifierhttp://hdl.handle.net/10722/225574
ISSN
2015 Impact Factor: 3.084
2015 SCImago Journal Rankings: 1.485

 

DC FieldValueLanguage
dc.contributor.authorYeung, CK-
dc.contributor.authorChan, HHL-
dc.date.accessioned2016-05-20T07:17:10Z-
dc.date.available2016-05-20T07:17:10Z-
dc.date.issued2004-
dc.identifier.citationAmerican Journal of Clinical Dermatology, 2004, v. 5 n. 1, p. 3-8-
dc.identifier.issn1175-0561-
dc.identifier.urihttp://hdl.handle.net/10722/225574-
dc.description.abstractAcneiform eruption, psoriasis, folliculitis, and maculopapular eruption have been described as adverse reactions to lithium therapy. In controlled studies, patients treated with lithium developed more cutaneous reactions, particularly acne and psoriasis, than patients receiving other psychotropics, with a prevalence in lithium-treated patients as high as 45%. Male patients taking lithium are more susceptible to developing cutaneous reactions than their female counterparts. Lithium tends to worsen or precipitate cutaneous conditions that are characterized by the pathological findings of neutrophilic infiltration. As lithium-related cutaneous adverse effects can be distressing to patients and may affect medication compliance, attention should be paid to skin problems in patients receiving lithium therapy. Management without cessation of lithium therapy is usually feasible except in some patients with psoriasis that is resistant to treatment. Paradoxically, therapeutic effects of topically applied lithium have been noted in seborrheic dermatitis and recurrent herpes infections.-
dc.languageeng-
dc.publisherAdis International Ltd. The Journal's web site is located at http://dermatology.adisonline.com/-
dc.relation.ispartofAmerican Journal of Clinical Dermatology-
dc.rightsThe final publication is available at Springer via http://dx.doi.org/[insert DOI]-
dc.subject.meshAntimanic Agents - adverse effects-
dc.subject.meshHumans-
dc.subject.meshLithium - adverse effects-
dc.subject.meshSkin Diseases - chemically induced - epidemiology - pathology-
dc.titleCutaneous Adverse Effects of Lithium: Epidemiology and Management-
dc.typeArticle-
dc.identifier.emailYeung, CK: yk890901@netvigator.com-
dc.identifier.emailChan, HHL: hhlchan@hkucc.hku.hk-
dc.identifier.doi10.2165/00128071-200405010-00002-
dc.identifier.pmid14979738-
dc.identifier.hkuros100469-
dc.identifier.volume5-
dc.identifier.issue1-
dc.identifier.spage3-
dc.identifier.epage8-
dc.publisher.placeNew Zealand-

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