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Article: Abnormal gastro-oesophageal reflux in Chinese with atypical chest pain

TitleAbnormal gastro-oesophageal reflux in Chinese with atypical chest pain
Authors
Issue Date1996
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH
Citation
Journal of Gastroenterology and Hepatology, 1996, v. 11 n. 8, p. 775-779 How to Cite?
AbstractAlthough atypical chest pain has been well described in the Western population, its frequency in Chinese is unknown. Over a period of 42 months, we studied 521 Chinese patients with chest pain and identified 108 patients (20.7%) whose pain was not related to cardiac causes, as determined by exercise ECG or cardiac catheterization. Using 24 h ambulatory pH monitoring and baseline oesophageal manometry, 28.7, 19.4 and 5.6% of these patients were found to have abnormal reflux parameters, abnormal manometric findings or both, respectively. There were significantly more patients complaining of chest pain during the study in the gastro-oesophageal reflux disease (GERD) group than in the non-GERD group (16/31 vs 20/77; P< 0.001). The lower oesophageal sphincter pressure was lower in those with abnormal reflex parameters than in those with normal reflux parameters (12.7±5.4 vs 17.8±5.8 mmHg; P< 0.05). There was no significant difference in symptoms, such as heartburn (54.8 vs 42.9%), regurgitation (38.7 vs 35.1%) and dysphagia (19.4 vs 24.7%), among the two groups. Non-specific changes were the most frequent baseline motility pattern. In conclusion, atypical chest pain and gastro-oesophageal reflux disease are not uncommon in Chinese and this deserves special emphasis as the continuation of anti-anginal drugs may aggravate their condition.
Persistent Identifierhttp://hdl.handle.net/10722/225156
ISSN
2015 Impact Factor: 3.322
2015 SCImago Journal Rankings: 1.190

 

DC FieldValueLanguage
dc.contributor.authorLau, GKK-
dc.contributor.authorHui, WM-
dc.contributor.authorLau, CP-
dc.contributor.authorHu, WHC-
dc.contributor.authorLai, KC-
dc.contributor.authorLam, SK-
dc.date.accessioned2016-04-25T06:21:27Z-
dc.date.available2016-04-25T06:21:27Z-
dc.date.issued1996-
dc.identifier.citationJournal of Gastroenterology and Hepatology, 1996, v. 11 n. 8, p. 775-779-
dc.identifier.issn0815-9319-
dc.identifier.urihttp://hdl.handle.net/10722/225156-
dc.description.abstractAlthough atypical chest pain has been well described in the Western population, its frequency in Chinese is unknown. Over a period of 42 months, we studied 521 Chinese patients with chest pain and identified 108 patients (20.7%) whose pain was not related to cardiac causes, as determined by exercise ECG or cardiac catheterization. Using 24 h ambulatory pH monitoring and baseline oesophageal manometry, 28.7, 19.4 and 5.6% of these patients were found to have abnormal reflux parameters, abnormal manometric findings or both, respectively. There were significantly more patients complaining of chest pain during the study in the gastro-oesophageal reflux disease (GERD) group than in the non-GERD group (16/31 vs 20/77; P< 0.001). The lower oesophageal sphincter pressure was lower in those with abnormal reflex parameters than in those with normal reflux parameters (12.7±5.4 vs 17.8±5.8 mmHg; P< 0.05). There was no significant difference in symptoms, such as heartburn (54.8 vs 42.9%), regurgitation (38.7 vs 35.1%) and dysphagia (19.4 vs 24.7%), among the two groups. Non-specific changes were the most frequent baseline motility pattern. In conclusion, atypical chest pain and gastro-oesophageal reflux disease are not uncommon in Chinese and this deserves special emphasis as the continuation of anti-anginal drugs may aggravate their condition.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwellpublishing.com/journals/JGH-
dc.relation.ispartofJournal of Gastroenterology and Hepatology-
dc.titleAbnormal gastro-oesophageal reflux in Chinese with atypical chest pain-
dc.typeArticle-
dc.identifier.emailLau, GKK: gkklau@netvigator.com-
dc.identifier.emailHui, WM: hrmehwm@hkucc.hku.hk-
dc.identifier.emailLau, CP: cplau@hku.hk-
dc.identifier.emailLai, KC: kclai@hkucc.hku.hk-
dc.identifier.emailLam, SK: hrmelsk@hkucc.hku.hk-
dc.identifier.doi10.1111/j.1440-1746.1996.tb00331.x-
dc.identifier.pmid8872778-
dc.identifier.hkuros22978-
dc.identifier.hkuros40443-
dc.identifier.volume11-
dc.identifier.issue8-
dc.identifier.spage775-
dc.identifier.epage779-
dc.publisher.placeAustralia-

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