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Article: Biomimetic mineralization and bioactivity of phosphorylated chitosan

TitleBiomimetic mineralization and bioactivity of phosphorylated chitosan
Authors
Chen, ZQLi, QLZen, QLi, QJiang, HBLiu, LKDarvell, BW
KeywordsBiocompatibility
Biomimesis
Chitosan (CS)
Mineralization
Phosphorylated Chitosan
Issue Date2005
PublisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net
Citation
Key Engineering Materials, 2005, v. 288-289, p. 429-432 How to Cite?
DOI: http://dx.doi.org/10.4028/www.scientific.net/KEM.288-289.429
AbstractPhosphorylated chitosans were synthesized as templates to manipulate hydroxyapatite (HA) crystal nucleation, growth and microstructure. Two kinds of insoluble phosphorylated chitosan were soaked in saturated Ca(OH)2 solution for 4 d and in 1.5× SBF (simulated body fluid) solutions for 14 d at 37 °C for biomimetic mineralization. A lower [P]-content of phosphorylated chitosan promoted greater mineralization than higher [P]-content. Phosphorylated chitosan inhibited osteoblast proliferation and differentiation in vitro, while calcium phosphate phosphorylated chitosan composites did not.
Persistent Identifierhttp://hdl.handle.net/10722/224089
ISSN
1013-9826
2020 SCImago Journal Rankings: 0.175
ISI Accession Number ID
WOS:000230426600105

 

DC FieldValueLanguage
dc.contributor.authorChen, ZQ-
dc.contributor.authorLi, QL-
dc.contributor.authorZen, Q-
dc.contributor.authorLi, Q-
dc.contributor.authorJiang, HB-
dc.contributor.authorLiu, LK-
dc.contributor.authorDarvell, BW-
dc.date.accessioned2016-03-23T02:31:09Z-
dc.date.available2016-03-23T02:31:09Z-
dc.date.issued2005-
dc.identifier.citationKey Engineering Materials, 2005, v. 288-289, p. 429-432-
dc.identifier.issn1013-9826-
dc.identifier.urihttp://hdl.handle.net/10722/224089-
dc.description.abstractPhosphorylated chitosans were synthesized as templates to manipulate hydroxyapatite (HA) crystal nucleation, growth and microstructure. Two kinds of insoluble phosphorylated chitosan were soaked in saturated Ca(OH)2 solution for 4 d and in 1.5× SBF (simulated body fluid) solutions for 14 d at 37 °C for biomimetic mineralization. A lower [P]-content of phosphorylated chitosan promoted greater mineralization than higher [P]-content. Phosphorylated chitosan inhibited osteoblast proliferation and differentiation in vitro, while calcium phosphate phosphorylated chitosan composites did not.-
dc.languageeng-
dc.publisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net-
dc.relation.ispartofKey Engineering Materials-
dc.subjectBiocompatibility-
dc.subjectBiomimesis-
dc.subjectChitosan (CS)-
dc.subjectMineralization-
dc.subjectPhosphorylated Chitosan-
dc.titleBiomimetic mineralization and bioactivity of phosphorylated chitosan-
dc.typeArticle-
dc.identifier.emailDarvell, BW: hrdubwd@hkucc.hku.hk-
dc.identifier.authorityDarvell, BW=rp00007-
dc.identifier.doi10.4028/www.scientific.net/KEM.288-289.429-
dc.identifier.hkuros97298-
dc.identifier.volume288-289-
dc.identifier.spage429-
dc.identifier.epage432-
dc.identifier.isiWOS:000230426600105-
dc.publisher.placeSwitzerland-
dc.identifier.issnl1013-9826-

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