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Conference Paper: Quantitative susceptibility mapping for the evaluation of subcortical iron abnormality in Parkinson's Disease with Dementia

TitleQuantitative susceptibility mapping for the evaluation of subcortical iron abnormality in Parkinson's Disease with Dementia
Authors
Issue Date2016
Citation
The 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore, 7-13 May 2016. In Conference Proceedings, 2016, p. 165, abstract no. 0685 How to Cite?
AbstractParkinson’s disease (PD) patients may develop other non-motor comorbidities when the disease progress. While increased nigral iron was considered as a biomarker of the disease, it was also believed that iron deposition is associated with the development of other non-motor symptoms. In this study, magnetic susceptibility as a surrogate of iron concentration was measured in six major subcortical brain regions on the QSM images. Increased magnetic susceptibilities were observed in hippocampus and amygdala of the PD patients with dementia, suggesting a possible association of iron with the development of dementia symptom in late stage of PD.
DescriptionScientific Session: Neurodegeneration - Non AD: no. 0685
Persistent Identifierhttp://hdl.handle.net/10722/223825

 

DC FieldValueLanguage
dc.contributor.authorLi, DTH-
dc.contributor.authorHui, ESK-
dc.contributor.authorChan, Q-
dc.contributor.authorYao, N-
dc.contributor.authorChua, S-
dc.contributor.authorMcAlonan, G-
dc.contributor.authorHo, SL-
dc.contributor.authorMak, HKF-
dc.date.accessioned2016-03-18T02:29:43Z-
dc.date.available2016-03-18T02:29:43Z-
dc.date.issued2016-
dc.identifier.citationThe 24th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2016), Singapore, 7-13 May 2016. In Conference Proceedings, 2016, p. 165, abstract no. 0685-
dc.identifier.urihttp://hdl.handle.net/10722/223825-
dc.descriptionScientific Session: Neurodegeneration - Non AD: no. 0685-
dc.description.abstractParkinson’s disease (PD) patients may develop other non-motor comorbidities when the disease progress. While increased nigral iron was considered as a biomarker of the disease, it was also believed that iron deposition is associated with the development of other non-motor symptoms. In this study, magnetic susceptibility as a surrogate of iron concentration was measured in six major subcortical brain regions on the QSM images. Increased magnetic susceptibilities were observed in hippocampus and amygdala of the PD patients with dementia, suggesting a possible association of iron with the development of dementia symptom in late stage of PD.-
dc.languageeng-
dc.relation.ispartofAnnual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine, ISMRM 2016-
dc.titleQuantitative susceptibility mapping for the evaluation of subcortical iron abnormality in Parkinson's Disease with Dementia-
dc.typeConference_Paper-
dc.identifier.emailHui, ESK: edshui@hku.hk-
dc.identifier.emailYao, N: nlyao@hku.hk-
dc.identifier.emailChua, S: sechua@hku.hk-
dc.identifier.emailMcAlonan, G: mcalonan@hkucc.hku.hk-
dc.identifier.emailHo, SL: slho@hku.hk-
dc.identifier.emailMak, HKF: makkf@hkucc.hku.hk-
dc.identifier.authorityHui, ESK=rp01832-
dc.identifier.authorityChua, S=rp00438-
dc.identifier.authorityMcAlonan, G=rp00475-
dc.identifier.authorityHo, SL=rp00240-
dc.identifier.authorityMak, HKF=rp00533-
dc.identifier.hkuros257225-
dc.identifier.spage165, abstract no. 0685-
dc.identifier.epage165, abstract no. 0685-

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