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Conference Paper: Morphological and microstructural changes in the eye and the brain in an experimental glaucoma model induced by crosslinking hydrogel injection

TitleMorphological and microstructural changes in the eye and the brain in an experimental glaucoma model induced by crosslinking hydrogel injection
Authors
Issue Date2015
Citation
The 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 2284 How to Cite?
AbstractGlaucoma is the second leading cause of blindness in the world and is an irreversible neurodegenerative disease of the visual system. To date, limited models have been available to provide sustained intraocular pressure elevation while keeping a clear visual axis for normal visual input to the eye. In this study, we characterized a novel experimental glaucoma model in rats using a crosslinking hydrogel that gives sustained intraocular pressure elevation and a transparent medium after intracameral injection. In vivo anatomical MRI, magic angle-enhanced MRI and diffusion tensor imaging were employed to determine the morphological and microstructural changes in the whole eye and the brain in this model.
DescriptionTraditional Poster Session: Neuro 2 - Novel Brain & Eye: no. 2284
Persistent Identifierhttp://hdl.handle.net/10722/220308

 

DC FieldValueLanguage
dc.contributor.authorHo, LC-
dc.contributor.authorConner, IP-
dc.contributor.authorYang, XL-
dc.contributor.authorvan der Merwe, Y-
dc.contributor.authorYu, Y-
dc.contributor.authorLeung, CK-
dc.contributor.authorSigal, IA-
dc.contributor.authorWu, EX-
dc.contributor.authorKim, SG-
dc.contributor.authorWollstein, G-
dc.contributor.authorSchuman, JS-
dc.contributor.authorChan, KC-
dc.date.accessioned2015-10-16T06:37:07Z-
dc.date.available2015-10-16T06:37:07Z-
dc.date.issued2015-
dc.identifier.citationThe 23rd Annual Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM) and SMRT 24th Annual Meeting, Toronto, ON., Canada, 30 May-5 June 2015, poster no. 2284-
dc.identifier.urihttp://hdl.handle.net/10722/220308-
dc.descriptionTraditional Poster Session: Neuro 2 - Novel Brain & Eye: no. 2284-
dc.description.abstractGlaucoma is the second leading cause of blindness in the world and is an irreversible neurodegenerative disease of the visual system. To date, limited models have been available to provide sustained intraocular pressure elevation while keeping a clear visual axis for normal visual input to the eye. In this study, we characterized a novel experimental glaucoma model in rats using a crosslinking hydrogel that gives sustained intraocular pressure elevation and a transparent medium after intracameral injection. In vivo anatomical MRI, magic angle-enhanced MRI and diffusion tensor imaging were employed to determine the morphological and microstructural changes in the whole eye and the brain in this model. -
dc.languageeng-
dc.relation.ispartofISMRM 23rd Annual Meeting & Exhibition cum SMRT 24th Annual Meeting Proceedings-
dc.titleMorphological and microstructural changes in the eye and the brain in an experimental glaucoma model induced by crosslinking hydrogel injection-
dc.typeConference_Paper-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityWu, EX=rp00193-
dc.identifier.hkuros255287-

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