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Conference Paper: Enrichment of committed, chondroitin sulfate-expressing human nucleus pulposus cells over progenitors under alginate encapsulation

TitleEnrichment of committed, chondroitin sulfate-expressing human nucleus pulposus cells over progenitors under alginate encapsulation
Authors
Issue Date2015
Citation
The 61st Annual Meeting of the Orthopaedic Research Society (ORS 2015), Las Vegas, NV., 28-31 March 2015. How to Cite?
AbstractINTRODUCTION: Accumulating evidence has suggested a heterogeneous NP cell population in adult human IVDs [1, 2], possibly a result of cells being at different differentiation states. The heterogeneous cell populations include the primitive NP cells (also regarded as notochordal NP cells) [1, 2], mature NP cells, and local disc progenitors [1] with various capacities in proteoglycan production other than chondrocytic NP cells. Cross-linked alginate hydrogel provides a favorable three-dimensional microenvironment for promotion of chondrogenic phenotype [3] with enhanced biosynthesis of proteoglycans (PGs) and collagen II. It has been widely used as a bioactive scaffold for engineering of ...
Persistent Identifierhttp://hdl.handle.net/10722/220266

 

DC FieldValueLanguage
dc.contributor.authorSun, Y-
dc.contributor.authorLv, M-
dc.contributor.authorZheng, Z-
dc.contributor.authorChan, D-
dc.contributor.authorCheung, K-
dc.contributor.authorLeung, V-
dc.date.accessioned2015-10-16T06:34:24Z-
dc.date.available2015-10-16T06:34:24Z-
dc.date.issued2015-
dc.identifier.citationThe 61st Annual Meeting of the Orthopaedic Research Society (ORS 2015), Las Vegas, NV., 28-31 March 2015.-
dc.identifier.urihttp://hdl.handle.net/10722/220266-
dc.description.abstractINTRODUCTION: Accumulating evidence has suggested a heterogeneous NP cell population in adult human IVDs [1, 2], possibly a result of cells being at different differentiation states. The heterogeneous cell populations include the primitive NP cells (also regarded as notochordal NP cells) [1, 2], mature NP cells, and local disc progenitors [1] with various capacities in proteoglycan production other than chondrocytic NP cells. Cross-linked alginate hydrogel provides a favorable three-dimensional microenvironment for promotion of chondrogenic phenotype [3] with enhanced biosynthesis of proteoglycans (PGs) and collagen II. It has been widely used as a bioactive scaffold for engineering of ...-
dc.languageeng-
dc.relation.ispartofAnnual Meeting of Orthopaedic Research Society, ORS 2015-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleEnrichment of committed, chondroitin sulfate-expressing human nucleus pulposus cells over progenitors under alginate encapsulation-
dc.typeConference_Paper-
dc.identifier.emailChan, D: chand@hku.hk-
dc.identifier.emailCheung, K: cheungmc@hku.hk-
dc.identifier.emailLeung, V: vicleung@hku.hk-
dc.identifier.authorityChan, D=rp00540-
dc.identifier.authorityCheung, K=rp00387-
dc.description.naturepostprint-
dc.identifier.hkuros256067-

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