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Conference Paper: Interplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis

TitleInterplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis
Authors
Issue Date2014
Citation
The 34th Annual Meeting of the Hong Kong Orthopaedic Association (HKOA), Hong Kong, 15-16 November 2014, p. 117 How to Cite?
AbstractBACKGROUND: Osteoarthritis (OA) is a common degenerative disease among elderly with some cases associated with hypertension. Endothelin-1 (ET-1) is a hypertension agonist which has been shown to induce type I collagen secretion and inhibit mineralisation in osteoblasts. Upregulation of transforming growth factor beta 1 (TGFβ-1) is associated with the onset of OA. Crosstalks between TGFβ-1 and ET-1 may increase the OA ...
DescriptionElectronic Poster Presentations: P40
Persistent Identifierhttp://hdl.handle.net/10722/217579

 

DC FieldValueLanguage
dc.contributor.authorTang, WC-
dc.contributor.authorWen, C-
dc.contributor.authorYan, CH-
dc.contributor.authorChiu, KY-
dc.date.accessioned2015-09-18T06:05:30Z-
dc.date.available2015-09-18T06:05:30Z-
dc.date.issued2014-
dc.identifier.citationThe 34th Annual Meeting of the Hong Kong Orthopaedic Association (HKOA), Hong Kong, 15-16 November 2014, p. 117-
dc.identifier.urihttp://hdl.handle.net/10722/217579-
dc.descriptionElectronic Poster Presentations: P40-
dc.description.abstractBACKGROUND: Osteoarthritis (OA) is a common degenerative disease among elderly with some cases associated with hypertension. Endothelin-1 (ET-1) is a hypertension agonist which has been shown to induce type I collagen secretion and inhibit mineralisation in osteoblasts. Upregulation of transforming growth factor beta 1 (TGFβ-1) is associated with the onset of OA. Crosstalks between TGFβ-1 and ET-1 may increase the OA ...-
dc.languageeng-
dc.relation.ispartofAnnual Meeting of the Hong Kong Orthopaedic Association, HKOA 2014-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleInterplay of transforming growth factor beta 1 and endothelin 1 signaling in subchondral osteoblast dysfunction in osteoarthritis-
dc.typeConference_Paper-
dc.identifier.emailWen, C: paulwen@hku.hk-
dc.identifier.emailYan, CH: yanchoi@hku.hk-
dc.identifier.emailChiu, KY: pkychiu@hkucc.hku.hk-
dc.identifier.authorityYan, CH=rp00303-
dc.identifier.authorityChiu, KY=rp00379-
dc.description.naturepostprint-
dc.identifier.hkuros251975-
dc.identifier.spage117-
dc.identifier.epage117-

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