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Article: Case Report of Relay Liver Transplantation With Graft Infected With Hepatitis B Virus

TitleCase Report of Relay Liver Transplantation With Graft Infected With Hepatitis B Virus
Authors
Issue Date2015
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/transproceed
Citation
Transplantation Proceedings, 2015, v. 47 n. 9, p. 2768-2770 How to Cite?
AbstractReuse of liver graft for transplantation is extremely uncommon. We report the 1st case of reuse of liver graft from a recipient who had hepatitis B virus (HBV) infection, 11 years after the 1st transplantation. Our relay liver transplantation challenged conventional thinking because of late reuse of graft in the presence of HBV infection. Moreover, both the 1st and the 2nd donors were of advanced age. The key questions were whether the liver graft could be reused safely, especially in the setting of HBV infection, and technical concerns during organ procurement and implantation. The absence of HBV replication was confirmed with negative hepatitis B surface antigen and undetectable serum HBV DNA in the 2nd donor. Based on our experience in managing HBV infection after liver transplantation, we were confident that the adequately suppressed HBV infection in the donor would not jeopardize graft function and that the graft would be able to withstand another ischemia-perfusion injury to continue to function well in our recipient. © 2015 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/217251
ISSN
2015 Impact Factor: 0.867
2015 SCImago Journal Rankings: 0.455
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, CLT-
dc.contributor.authorCheung, TT-
dc.contributor.authorShe, WH-
dc.contributor.authorChan, SC-
dc.contributor.authorLo, CM-
dc.date.accessioned2015-09-18T05:53:41Z-
dc.date.available2015-09-18T05:53:41Z-
dc.date.issued2015-
dc.identifier.citationTransplantation Proceedings, 2015, v. 47 n. 9, p. 2768-2770-
dc.identifier.issn0041-1345-
dc.identifier.urihttp://hdl.handle.net/10722/217251-
dc.description.abstractReuse of liver graft for transplantation is extremely uncommon. We report the 1st case of reuse of liver graft from a recipient who had hepatitis B virus (HBV) infection, 11 years after the 1st transplantation. Our relay liver transplantation challenged conventional thinking because of late reuse of graft in the presence of HBV infection. Moreover, both the 1st and the 2nd donors were of advanced age. The key questions were whether the liver graft could be reused safely, especially in the setting of HBV infection, and technical concerns during organ procurement and implantation. The absence of HBV replication was confirmed with negative hepatitis B surface antigen and undetectable serum HBV DNA in the 2nd donor. Based on our experience in managing HBV infection after liver transplantation, we were confident that the adequately suppressed HBV infection in the donor would not jeopardize graft function and that the graft would be able to withstand another ischemia-perfusion injury to continue to function well in our recipient. © 2015 Elsevier Inc. All rights reserved.-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/transproceed-
dc.relation.ispartofTransplantation Proceedings-
dc.rights© <year>. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/-
dc.titleCase Report of Relay Liver Transplantation With Graft Infected With Hepatitis B Virus-
dc.typeArticle-
dc.identifier.emailWong, CLT: wongtcl@hku.hk-
dc.identifier.emailShe, WH: brianshe@hku.hk-
dc.identifier.emailCheung, TT: cheung68@hku.hk-
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hk-
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hk-
dc.identifier.authorityWong, CLT=rp01679-
dc.identifier.authorityChan, SC=rp01568-
dc.identifier.authorityLo, CM=rp00412-
dc.identifier.doi10.1016/j.transproceed.2015.09.036-
dc.identifier.pmid26680090-
dc.identifier.scopuseid_2-s2.0-84949482557-
dc.identifier.hkuros251762-
dc.identifier.volume47-
dc.identifier.issue9-
dc.identifier.spage2768-
dc.identifier.epage2770-
dc.identifier.isiWOS:000366790100057-
dc.publisher.placeUnited States-

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