File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)

Article: Postoperative nomogram for predicting disease-specific death and recurrence in papillary thyroid carcinoma

TitlePostoperative nomogram for predicting disease-specific death and recurrence in papillary thyroid carcinoma
Authors
Issue Date2015
Citation
Head & Neck, 2015 How to Cite?
AbstractBackground: A nomogram could provide individualized prognostic for papillary thyroid carcinoma (PTC). The purpose of our study was to develop and validate a new nomogram. Methods: Consecutive patients with PTC from 2 different institutions were analyzed and divided into the development (n = 849) and validation (n = 275) sets. The former was used for formulating a nomogram in predicting disease-specific death and recurrence, whereas the latter was for validation (by area under the curve [AUC]). Results: The nomogram had excellent discrimination in predicting 10-year disease-specific death and recurrence (0.984; 0.969–0.998; and 0.743; 0.658–0.828; respectively). A score <30 meant 100% of the patients survived at 10 years and those who died within 10 years had a score ≥30. A score <17 meant almost all the patients (91.04%) were disease-free within 10 years. Conclusion: Using a competing-risk model, a nomogram was created with excellent discriminatory ability and accuracy in predicting 10-year disease-specific death and recurrence for PTC. Our results implied its potential for wider use in other populations.
Persistent Identifierhttp://hdl.handle.net/10722/217139

 

DC FieldValueLanguage
dc.contributor.authorLang, HHB-
dc.contributor.authorWong, CKH-
dc.contributor.authorYu, HW-
dc.contributor.authorLee, KE-
dc.date.accessioned2015-09-18T05:49:09Z-
dc.date.available2015-09-18T05:49:09Z-
dc.date.issued2015-
dc.identifier.citationHead & Neck, 2015-
dc.identifier.urihttp://hdl.handle.net/10722/217139-
dc.description.abstractBackground: A nomogram could provide individualized prognostic for papillary thyroid carcinoma (PTC). The purpose of our study was to develop and validate a new nomogram. Methods: Consecutive patients with PTC from 2 different institutions were analyzed and divided into the development (n = 849) and validation (n = 275) sets. The former was used for formulating a nomogram in predicting disease-specific death and recurrence, whereas the latter was for validation (by area under the curve [AUC]). Results: The nomogram had excellent discrimination in predicting 10-year disease-specific death and recurrence (0.984; 0.969–0.998; and 0.743; 0.658–0.828; respectively). A score <30 meant 100% of the patients survived at 10 years and those who died within 10 years had a score ≥30. A score <17 meant almost all the patients (91.04%) were disease-free within 10 years. Conclusion: Using a competing-risk model, a nomogram was created with excellent discriminatory ability and accuracy in predicting 10-year disease-specific death and recurrence for PTC. Our results implied its potential for wider use in other populations.-
dc.languageeng-
dc.relation.ispartofHead & Neck-
dc.titlePostoperative nomogram for predicting disease-specific death and recurrence in papillary thyroid carcinoma-
dc.typeArticle-
dc.identifier.emailLang, HHB: blang@hkucc.hku.hk-
dc.identifier.emailWong, CKH: carlosho@hku.hk-
dc.identifier.authorityLang, HHB=rp01828-
dc.identifier.authorityWong, CKH=rp01931-
dc.identifier.doi10.1002/hed.24201-
dc.identifier.hkuros252713-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats