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Article: Electroanalytical and biocompatibility studies on carboxylated poly(vinyl chloride) membranes for microfabricated array sensors

TitleElectroanalytical and biocompatibility studies on carboxylated poly(vinyl chloride) membranes for microfabricated array sensors
Authors
Issue Date1994
Citation
The Analyst, 1994, v. 119, n. 11, p. 2283-2292 How to Cite?
AbstractPotassium ion-selective and pH membrane electrodes based on neutral carrier ionophores for K+ (valinomycin) and H+ (TDDA and ETH 5294), respectively, immobilized in carboxylated PVC (PVC-COOH) with normal (classical) and reduced amounts of plasticizer, were investigated with respect to their general analytical performances (linear range, slope, detection limit, selectivity, internal membrane resistance), their biocompatibility and cellular responses. The analytical performance of potassium selective electrodes was not affected by reducing the plasticizer content from 66% (m/m) to about 33% (m/m) while that of pH electrodes was significantly changed at the lower plasticizer concentration level. The adhesive properties of PVC-COOH membranes to an inert substrate such as polyimide-coated Kapton are greatly improved by reducing the plasticizer content of the membrane. In addition, as was reported earlier by this group, improved biocompatibility was observed with these membranes relative to those with increased plasticizer content. A ratio of 1: 1 m/m for PVC-COOH to plasticizer is recommended for the construction of planar ISEs without massive use of internal solution.
Persistent Identifierhttp://hdl.handle.net/10722/216140
ISSN
2015 Impact Factor: 4.033
2015 SCImago Journal Rankings: 1.300

 

DC FieldValueLanguage
dc.contributor.authorCosofret, Vasile V.-
dc.contributor.authorErdösy, Miklós-
dc.contributor.authorBuck, Richard P.-
dc.contributor.authorKao, Weiyuan J.-
dc.contributor.authorAnderson, James M.-
dc.contributor.authorLindner, Ernö-
dc.contributor.authorNeuman, Michael R.-
dc.date.accessioned2015-08-25T10:21:35Z-
dc.date.available2015-08-25T10:21:35Z-
dc.date.issued1994-
dc.identifier.citationThe Analyst, 1994, v. 119, n. 11, p. 2283-2292-
dc.identifier.issn0003-2654-
dc.identifier.urihttp://hdl.handle.net/10722/216140-
dc.description.abstractPotassium ion-selective and pH membrane electrodes based on neutral carrier ionophores for K+ (valinomycin) and H+ (TDDA and ETH 5294), respectively, immobilized in carboxylated PVC (PVC-COOH) with normal (classical) and reduced amounts of plasticizer, were investigated with respect to their general analytical performances (linear range, slope, detection limit, selectivity, internal membrane resistance), their biocompatibility and cellular responses. The analytical performance of potassium selective electrodes was not affected by reducing the plasticizer content from 66% (m/m) to about 33% (m/m) while that of pH electrodes was significantly changed at the lower plasticizer concentration level. The adhesive properties of PVC-COOH membranes to an inert substrate such as polyimide-coated Kapton are greatly improved by reducing the plasticizer content of the membrane. In addition, as was reported earlier by this group, improved biocompatibility was observed with these membranes relative to those with increased plasticizer content. A ratio of 1: 1 m/m for PVC-COOH to plasticizer is recommended for the construction of planar ISEs without massive use of internal solution.-
dc.languageeng-
dc.relation.ispartofThe Analyst-
dc.titleElectroanalytical and biocompatibility studies on carboxylated poly(vinyl chloride) membranes for microfabricated array sensors-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1039/AN9941902283-
dc.identifier.pmid7872483-
dc.identifier.scopuseid_2-s2.0-0028053794-
dc.identifier.volume119-
dc.identifier.issue11-
dc.identifier.spage2283-
dc.identifier.epage2292-

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