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  Patent History
  • Application
    US 12/3411387 2012-03-02
  • Granted
    US 20120225101 2012-09-06
  Patent Family
Supplementary

granted patent: Multifunctional in situ polymerized network via thiol-ene and thiol-maleimide chemistry

TitleMultifunctional in situ polymerized network via thiol-ene and thiol-maleimide chemistry
Granted PatentUS 20120225101
Granted Date2012-09-06
Priority Date2012-03-02 US 12/3411387
2011-03-02 US 12/1448543P
Inventors
Issue Date2012
Citation
US Patent US 20120225101. Washington, DC: US Patent and Trademark Office (USPTO), 2012 How to Cite?
AbstractBiomaterials that support cell attachment and growth are provided. In one aspect, biomaterials are provided comprising a first polymer matrix comprising reactive amino moieties and a second polymer matrix that interpenetrates with the first polymer matrix, where the second polymer matrix comprises a poly(alkylene oxide) comprising two or more alkylene oxide oligomers joined by gamma-thioether carbonyl linkages. In another aspect, biomaterials are provided comprising at least one biopolymer comprising amino groups, thiol groups, and bifunctional modifiers connecting at least some of the amino groups to at least some of the thiol groups; and at least one poly(alkylene oxide) cross-linked to at least two thiol groups of the biopolymer. The biomaterials may further comprise a pharmacologically active agent or cells.; Methods of administering such biomaterials to a patient in need thereof are also provided.
Persistent Identifierhttp://hdl.handle.net/10722/216134
References

 

DC FieldValueLanguage
dc.date.accessioned2015-08-25T10:21:19Z-
dc.date.available2015-08-25T10:21:19Z-
dc.date.issued2012-
dc.identifier.citationUS Patent US 20120225101. Washington, DC: US Patent and Trademark Office (USPTO), 2012-
dc.identifier.urihttp://hdl.handle.net/10722/216134-
dc.description.abstractBiomaterials that support cell attachment and growth are provided. In one aspect, biomaterials are provided comprising a first polymer matrix comprising reactive amino moieties and a second polymer matrix that interpenetrates with the first polymer matrix, where the second polymer matrix comprises a poly(alkylene oxide) comprising two or more alkylene oxide oligomers joined by gamma-thioether carbonyl linkages. In another aspect, biomaterials are provided comprising at least one biopolymer comprising amino groups, thiol groups, and bifunctional modifiers connecting at least some of the amino groups to at least some of the thiol groups; and at least one poly(alkylene oxide) cross-linked to at least two thiol groups of the biopolymer. The biomaterials may further comprise a pharmacologically active agent or cells.; Methods of administering such biomaterials to a patient in need thereof are also provided.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleMultifunctional in situ polymerized network via thiol-ene and thiol-maleimide chemistry-
dc.typePatent-
dc.identifier.authorityKAO, WEIYUAN J=rp02076-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorKAO, WEIYUAN J-
dc.contributor.inventorFU, YAO-
patents.identifier.applicationUS 12/3411387-
patents.identifier.grantedUS 20120225101-
patents.description.assigneeKAO WEIYUAN J [US]; FU YAO [US]-
patents.description.countryUnited States of America-
patents.date.granted2012-09-06-
dc.relation.referencesUS 2009117078 (A1) 2009-05-07-
dc.relation.referencesU S7928069 (B2) 2011-04-19-
patents.date.application2012-03-02-
patents.date.priority2012-03-02 US 12/3411387-
patents.date.priority2011-03-02 US 12/1448543P-
patents.description.ccus-
patents.relation.familyU S8980295 (B2) 2015-03-17-
patents.description.kindA1-
patents.typePatent_granted-

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