File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Nasopharyngeal carcinoma: Salvage of local recurrence

TitleNasopharyngeal carcinoma: Salvage of local recurrence
Authors
KeywordsNasopharyngeal carcinoma
Nasopharyngectomy
Radiotherapy
Recurrent
Toxicity
Chemotherapy
Efficacy
Issue Date2012
Citation
Oral Oncology, 2012, v. 48, n. 9, p. 768-774 How to Cite?
AbstractLocal control of nasopharyngeal carcinoma has substantially improved with advancing radiotherapy technology and appropriate combination with chemotherapy. However, when local recurrence occurs, this is one of the most difficult challenges. Aggressive treatment is indicated because long term salvage is achievable particularly for early recurrence, but high risk of complications is a serious concern. Treatment options include different methods of surgery and/or re-irradiation with/without chemotherapy. Available information in the literature is grossly inadequate; most reports compose of small series of highly selected patients with heterogeneous characteristics and treatment. No randomized trials have been performed to evaluate the therapeutic ratio of different treatment methods. This article reviews available treatment options, their therapeutic benefits and risks of complications; the objective is to provide information for developing treatment recommendations and suggestions for future improvement. © 2012 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/213976
ISSN
2015 Impact Factor: 4.286
2015 SCImago Journal Rankings: 1.764

 

DC FieldValueLanguage
dc.contributor.authorLee, Anne W M-
dc.contributor.authorFee, Willard E.-
dc.contributor.authorNg, W. T.-
dc.contributor.authorChan, L. K.-
dc.date.accessioned2015-08-19T13:41:25Z-
dc.date.available2015-08-19T13:41:25Z-
dc.date.issued2012-
dc.identifier.citationOral Oncology, 2012, v. 48, n. 9, p. 768-774-
dc.identifier.issn1368-8375-
dc.identifier.urihttp://hdl.handle.net/10722/213976-
dc.description.abstractLocal control of nasopharyngeal carcinoma has substantially improved with advancing radiotherapy technology and appropriate combination with chemotherapy. However, when local recurrence occurs, this is one of the most difficult challenges. Aggressive treatment is indicated because long term salvage is achievable particularly for early recurrence, but high risk of complications is a serious concern. Treatment options include different methods of surgery and/or re-irradiation with/without chemotherapy. Available information in the literature is grossly inadequate; most reports compose of small series of highly selected patients with heterogeneous characteristics and treatment. No randomized trials have been performed to evaluate the therapeutic ratio of different treatment methods. This article reviews available treatment options, their therapeutic benefits and risks of complications; the objective is to provide information for developing treatment recommendations and suggestions for future improvement. © 2012 Elsevier Ltd. All rights reserved.-
dc.languageeng-
dc.relation.ispartofOral Oncology-
dc.subjectNasopharyngeal carcinoma-
dc.subjectNasopharyngectomy-
dc.subjectRadiotherapy-
dc.subjectRecurrent-
dc.subjectToxicity-
dc.subjectChemotherapy-
dc.subjectEfficacy-
dc.titleNasopharyngeal carcinoma: Salvage of local recurrence-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.oraloncology.2012.02.017-
dc.identifier.pmid22425246-
dc.identifier.scopuseid_2-s2.0-84865187392-
dc.identifier.hkuros265727-
dc.identifier.volume48-
dc.identifier.issue9-
dc.identifier.spage768-
dc.identifier.epage774-
dc.identifier.eissn1879-0593-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats