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Article: The superiority of hybrid-volumetric arc therapy (VMAT) technique over double arcs VMAT and 3D-conformal technique in the treatment of locally advanced non-small cell lung cancer - A planning study

TitleThe superiority of hybrid-volumetric arc therapy (VMAT) technique over double arcs VMAT and 3D-conformal technique in the treatment of locally advanced non-small cell lung cancer - A planning study
Authors
KeywordsVolumetric modulated arc therapy
Planning study
Non-small cell lung cancer
RapidArc
Issue Date2011
Citation
Radiotherapy and Oncology, 2011, v. 101, n. 2, p. 298-302 How to Cite?
AbstractPurpose: To compare the dosimetric performance of three different treatment techniques - conformal radiotherapy (CRT), double arcs volumetric modulated arc therapy (RapidArc, RA) and Hybrid-RapidArc (H-RA) for locally-advanced non-small cell lung cancer (NSCLC). Material and methods: CRT, RA and H-RA plans were optimized for 24 stage III NSCLC patients. The target prescription dose was 60 Gy. CRT consisted of 5-7 coplanar fields, while RA comprised of two 204 o arcs. H-RA referred to two 204 o arcs plus 2 static fields, which accounted for approximately half of the total dose. The plans were optimized to fulfill the departmental plan acceptance criteria. Results: RA and H-RA yielded a 20% better conformity compared with CRT. Lung volume receiving >20 Gy (V20) and mean lung dose (MLD) were the lowest in H-RA (V20 1.7% and 2.1% lower, MLD 0.59 Gy and 0.41 Gy lower than CRT & RA respectively) without jeopardizing the low-dose lung volume (V5). H-RA plans gave the lowest mean maximum spinal cord dose (34.4 Gy, 3.9 Gy < CRT and 2.2 Gy < RA plans) and NTCP of lung. Higher average MU per fraction (addition 52.4 MU) was observed with a reduced treatment time compared with CRT plans. Conclusion: The H-RA technique was superior in dosimetric outcomes for treating locally-advanced NSCLC compared to CRT and RA. © 2011 Elsevier Ireland Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/213955
ISSN
2015 Impact Factor: 4.817
2015 SCImago Journal Rankings: 2.654

 

DC FieldValueLanguage
dc.contributor.authorChan, Oscar S H-
dc.contributor.authorLee, Michael C H-
dc.contributor.authorHung, Albert W M-
dc.contributor.authorChang, Amy T Y-
dc.contributor.authorYeung, Rebecca M W-
dc.contributor.authorLee, Anne W M-
dc.date.accessioned2015-08-19T13:41:21Z-
dc.date.available2015-08-19T13:41:21Z-
dc.date.issued2011-
dc.identifier.citationRadiotherapy and Oncology, 2011, v. 101, n. 2, p. 298-302-
dc.identifier.issn0167-8140-
dc.identifier.urihttp://hdl.handle.net/10722/213955-
dc.description.abstractPurpose: To compare the dosimetric performance of three different treatment techniques - conformal radiotherapy (CRT), double arcs volumetric modulated arc therapy (RapidArc, RA) and Hybrid-RapidArc (H-RA) for locally-advanced non-small cell lung cancer (NSCLC). Material and methods: CRT, RA and H-RA plans were optimized for 24 stage III NSCLC patients. The target prescription dose was 60 Gy. CRT consisted of 5-7 coplanar fields, while RA comprised of two 204 o arcs. H-RA referred to two 204 o arcs plus 2 static fields, which accounted for approximately half of the total dose. The plans were optimized to fulfill the departmental plan acceptance criteria. Results: RA and H-RA yielded a 20% better conformity compared with CRT. Lung volume receiving >20 Gy (V20) and mean lung dose (MLD) were the lowest in H-RA (V20 1.7% and 2.1% lower, MLD 0.59 Gy and 0.41 Gy lower than CRT & RA respectively) without jeopardizing the low-dose lung volume (V5). H-RA plans gave the lowest mean maximum spinal cord dose (34.4 Gy, 3.9 Gy < CRT and 2.2 Gy < RA plans) and NTCP of lung. Higher average MU per fraction (addition 52.4 MU) was observed with a reduced treatment time compared with CRT plans. Conclusion: The H-RA technique was superior in dosimetric outcomes for treating locally-advanced NSCLC compared to CRT and RA. © 2011 Elsevier Ireland Ltd. All rights reserved.-
dc.languageeng-
dc.relation.ispartofRadiotherapy and Oncology-
dc.subjectVolumetric modulated arc therapy-
dc.subjectPlanning study-
dc.subjectNon-small cell lung cancer-
dc.subjectRapidArc-
dc.titleThe superiority of hybrid-volumetric arc therapy (VMAT) technique over double arcs VMAT and 3D-conformal technique in the treatment of locally advanced non-small cell lung cancer - A planning study-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.radonc.2011.08.015-
dc.identifier.pmid21907438-
dc.identifier.scopuseid_2-s2.0-81755166367-
dc.identifier.hkuros266276-
dc.identifier.volume101-
dc.identifier.issue2-
dc.identifier.spage298-
dc.identifier.epage302-
dc.identifier.eissn1879-0887-

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