File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: In-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool

TitleIn-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool
Authors
KeywordsYoung's modulus
Embryogenic stages
Fruit fly drosophila embryo
Mechanical impedance
Microforce
Microinjection
Stiffness
Issue Date2008
Citation
2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008, 2008, p. 31-36 How to Cite?
AbstractThe fruit fly Drosophila is one of the most important model organisms in genetics and developmental biology research. To better understand the biomechanical properties involved in Drosophila embryo research, this work presents a mechanical characterization of living Drosophila embryos through the stages of embryogenesis. Measurements of the mechanical forces of Drosophila embryos are implemented using a novel, in-situ, and minimally invasive force sensing tool with a resolution in the range of μN. The measurements offer an essential understanding of penetration force profiles during the microinjection of Drosophila embryos. Sequentially quantitative evaluation and analysis of the mechanical properties, such as Young's modulus, stiffness, and mechanical impedance of living Drosophila embryos are performed by extracting the force measurements throughout the stages of embryogenesis. The evaluation provides a critical step toward better understanding of the biomechanical properties of Drosophila embryos during embryogenesis, and could contribute to more efficient and significant genetic and embryonic development research on Drosophila. © 2008 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/213060

 

DC FieldValueLanguage
dc.contributor.authorShen, Yantao-
dc.contributor.authorXi, Ning-
dc.contributor.authorZhang, Rui-
dc.date.accessioned2015-07-28T04:06:00Z-
dc.date.available2015-07-28T04:06:00Z-
dc.date.issued2008-
dc.identifier.citation2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008, 2008, p. 31-36-
dc.identifier.urihttp://hdl.handle.net/10722/213060-
dc.description.abstractThe fruit fly Drosophila is one of the most important model organisms in genetics and developmental biology research. To better understand the biomechanical properties involved in Drosophila embryo research, this work presents a mechanical characterization of living Drosophila embryos through the stages of embryogenesis. Measurements of the mechanical forces of Drosophila embryos are implemented using a novel, in-situ, and minimally invasive force sensing tool with a resolution in the range of μN. The measurements offer an essential understanding of penetration force profiles during the microinjection of Drosophila embryos. Sequentially quantitative evaluation and analysis of the mechanical properties, such as Young's modulus, stiffness, and mechanical impedance of living Drosophila embryos are performed by extracting the force measurements throughout the stages of embryogenesis. The evaluation provides a critical step toward better understanding of the biomechanical properties of Drosophila embryos during embryogenesis, and could contribute to more efficient and significant genetic and embryonic development research on Drosophila. © 2008 IEEE.-
dc.languageeng-
dc.relation.ispartof2008 IEEE International Conference on Robotics and Biomimetics, ROBIO 2008-
dc.subjectYoung's modulus-
dc.subjectEmbryogenic stages-
dc.subjectFruit fly drosophila embryo-
dc.subjectMechanical impedance-
dc.subjectMicroforce-
dc.subjectMicroinjection-
dc.subjectStiffness-
dc.titleIn-situ mechanical property evaluation of different stage drosophila embryos with a minimally invasive microforce sensing tool-
dc.typeConference_Paper-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1109/ROBIO.2009.4912975-
dc.identifier.scopuseid_2-s2.0-70349166767-
dc.identifier.spage31-
dc.identifier.epage36-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats