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Article: Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making

TitleResting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making
Authors
Issue Date2013
PublisherSociety for Neuroscience. The Journal's web site is located at http://www.jneurosci.org
Citation
Journal of Neuroscience, 2013, v. 33 n. 11, p. 4886-4895 How to Cite?
AbstractIncreasing neuroimaging evidence suggests an association between impulsive decision-making behavior and task-related brain activity. However, the relationship between impulsivity in decision-making and resting-state brain activity remains unknown. To address this issue, we used functional MRI to record brain activity from human adults during a resting state and during a delay discounting task (DDT) that requires choosing between an immediate smaller reward and a larger delayed reward. In experiment I, we identified four DDT-related brain networks. The money network (the striatum, posterior cingulate cortex, etc.) and the time network (the medial and dorsolateral prefrontal cortices, etc.) were associated with the valuation process; the frontoparietal network and the dorsal anterior cingulate cortex–anterior insular cortex network were related to the choice process. Moreover, we found that the resting-state functional connectivity of the brain regions in these networks was significantly correlated with participants' discounting rate, a behavioral index of impulsivity during the DDT. In experiment II, we tested an independent group of subjects and demonstrated that this resting-state functional connectivity was able to predict individuals' discounting rates. Together, these findings suggest that resting-state functional organization of the human brain may be a biomarker of impulsivity and can predict economic decision-making behavior.
Persistent Identifierhttp://hdl.handle.net/10722/212297
ISSN
2015 Impact Factor: 5.924
2015 SCImago Journal Rankings: 5.105

 

DC FieldValueLanguage
dc.contributor.authorLi, N-
dc.contributor.authorMa, N-
dc.contributor.authorLiu, Y-
dc.contributor.authorHe, XS-
dc.contributor.authorSun, D-
dc.contributor.authorFu, XM-
dc.contributor.authorZhang, XC-
dc.contributor.authorHan, SH-
dc.contributor.authorZhang, DR-
dc.date.accessioned2015-07-21T02:31:07Z-
dc.date.available2015-07-21T02:31:07Z-
dc.date.issued2013-
dc.identifier.citationJournal of Neuroscience, 2013, v. 33 n. 11, p. 4886-4895-
dc.identifier.issn0270-6474-
dc.identifier.urihttp://hdl.handle.net/10722/212297-
dc.description.abstractIncreasing neuroimaging evidence suggests an association between impulsive decision-making behavior and task-related brain activity. However, the relationship between impulsivity in decision-making and resting-state brain activity remains unknown. To address this issue, we used functional MRI to record brain activity from human adults during a resting state and during a delay discounting task (DDT) that requires choosing between an immediate smaller reward and a larger delayed reward. In experiment I, we identified four DDT-related brain networks. The money network (the striatum, posterior cingulate cortex, etc.) and the time network (the medial and dorsolateral prefrontal cortices, etc.) were associated with the valuation process; the frontoparietal network and the dorsal anterior cingulate cortex–anterior insular cortex network were related to the choice process. Moreover, we found that the resting-state functional connectivity of the brain regions in these networks was significantly correlated with participants' discounting rate, a behavioral index of impulsivity during the DDT. In experiment II, we tested an independent group of subjects and demonstrated that this resting-state functional connectivity was able to predict individuals' discounting rates. Together, these findings suggest that resting-state functional organization of the human brain may be a biomarker of impulsivity and can predict economic decision-making behavior.-
dc.languageeng-
dc.publisherSociety for Neuroscience. The Journal's web site is located at http://www.jneurosci.org-
dc.relation.ispartofJournal of Neuroscience-
dc.rightsJournal of Neuroscience. Copyright © Society for Neuroscience.-
dc.titleResting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making-
dc.typeArticle-
dc.identifier.emailSun, D: sundelin@hku.hk-
dc.identifier.authoritySun, D=rp00873-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1523/JNEUROSCI.1342-12.2013-
dc.identifier.pmid23486959-
dc.identifier.hkuros243711-
dc.identifier.volume33-
dc.identifier.issue11-
dc.identifier.spage4886-
dc.identifier.epage4895-
dc.publisher.placeUnited States-

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