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Conference Paper: Association between serum concentrations of soluble lectin-like oxidized low density lipoprotein receptor-1 and serum amyloid A in type 2 diabetes
| Title | Association between serum concentrations of soluble lectin-like oxidized low density lipoprotein receptor-1 and serum amyloid A in type 2 diabetes |
|---|---|
| Authors | |
| Keywords | Medical sciences Endocrinology |
| Issue Date | 2014 |
| Publisher | Elsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/diabres |
| Citation | The 10th International Diabetes Federation Western Pacific Region Congress and the 6th AASD Scientific Meeting, Singapore, 21-24 November 2014. In Diabetes Research and Clinical Practice, 2014, v. 106 suppl. 1, p. S56 How to Cite? |
| Abstract | BACKGROUND: Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) mediates the uptake of oxidized LDL in endothelial cells and macrophages, and has been implicated in the pathogenesis of vascular inflammation and atherosclerosis. The extracellular domain of LOX-1 can be proteolytically cleaved and released as a soluble form (sLOX-1). It has been suggested that circulating level of sLOX-1 reflects LOX-1 expression and can act as a biomarker. LOX-1 expression is inducible and recent experimental data have shown that serum amyloid A (SAA), an acute phase protein, can induce LOX-1 expression in macrophages in vitro. Since type 2 diabetes is associated with subclinical inflammation, we have evaluated whether serum sLOX-1 level is ... |
| Description | Posters: no. PO020 This journal suppl. entitled: Abstracts of the 10th International Diabetes Federation-Western Pacific Region Congress and the 6th AASD Scientific Meeting |
| Persistent Identifier | http://hdl.handle.net/10722/211521 |
| ISSN | 2021 Impact Factor: 8.180 2020 SCImago Journal Rankings: 1.605 |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, CH | - |
| dc.contributor.author | Shiu, SWM | - |
| dc.contributor.author | Wong, Y | - |
| dc.contributor.author | Tan, K | - |
| dc.date.accessioned | 2015-07-16T04:10:39Z | - |
| dc.date.available | 2015-07-16T04:10:39Z | - |
| dc.date.issued | 2014 | - |
| dc.identifier.citation | The 10th International Diabetes Federation Western Pacific Region Congress and the 6th AASD Scientific Meeting, Singapore, 21-24 November 2014. In Diabetes Research and Clinical Practice, 2014, v. 106 suppl. 1, p. S56 | - |
| dc.identifier.issn | 0168-8227 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/211521 | - |
| dc.description | Posters: no. PO020 | - |
| dc.description | This journal suppl. entitled: Abstracts of the 10th International Diabetes Federation-Western Pacific Region Congress and the 6th AASD Scientific Meeting | - |
| dc.description.abstract | BACKGROUND: Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) mediates the uptake of oxidized LDL in endothelial cells and macrophages, and has been implicated in the pathogenesis of vascular inflammation and atherosclerosis. The extracellular domain of LOX-1 can be proteolytically cleaved and released as a soluble form (sLOX-1). It has been suggested that circulating level of sLOX-1 reflects LOX-1 expression and can act as a biomarker. LOX-1 expression is inducible and recent experimental data have shown that serum amyloid A (SAA), an acute phase protein, can induce LOX-1 expression in macrophages in vitro. Since type 2 diabetes is associated with subclinical inflammation, we have evaluated whether serum sLOX-1 level is ... | - |
| dc.language | eng | - |
| dc.publisher | Elsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/diabres | - |
| dc.relation.ispartof | Diabetes Research and Clinical Practice | - |
| dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication in Diabetes Research and Clinical Practice. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Diabetes Research and Clinical Practice, vol. 106, suppl. 1, November 2014. DOI: 10.1016/S0168-8227(14)70315-8 | - |
| dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
| dc.subject | Medical sciences | - |
| dc.subject | Endocrinology | - |
| dc.title | Association between serum concentrations of soluble lectin-like oxidized low density lipoprotein receptor-1 and serum amyloid A in type 2 diabetes | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Shiu, SWM: swmshiu@hku.hk | - |
| dc.identifier.email | Wong, Y: ywong@hku.hk | - |
| dc.identifier.email | Tan, K: kcbtan@hkucc.hku.hk | - |
| dc.identifier.authority | Tan, K=rp00402 | - |
| dc.description.nature | postprint | - |
| dc.identifier.doi | 10.1016/S0168-8227(14)70315-8 | - |
| dc.identifier.hkuros | 245103 | - |
| dc.identifier.volume | 106 | - |
| dc.identifier.issue | suppl. 1 | - |
| dc.identifier.spage | S56, abstract PO020 | - |
| dc.identifier.epage | S56, abstract PO020 | - |
| dc.identifier.isi | WOS:000361124300110 | - |
| dc.publisher.place | Ireland | - |
| dc.identifier.issnl | 0168-8227 | - |