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Conference Paper: Prevention of glyceryl trinitrate tolerance by flavonoids

TitlePrevention of glyceryl trinitrate tolerance by flavonoids
Authors
Issue Date2014
PublisherMedcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3
Citation
The 18th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM 2014), Hong Kong, 1 November 2014. In Journal of the Hong Kong College of Cardiology, 2014, v. 22 n. 2, p. 55, abstract CP7 How to Cite?
AbstractGlyceryl trinitrate (GTN) is one of the most widely used anti-ischemic. However, the development of tolerance after continuous application for 24 to 72 hours limits its clinical utility. Tolerance appears to be associated with the oxidative stress induced by GTN in blood vessels. Flavonoids are important components in herbal medicine. They have antioxidative effect and potentiate vascular relaxation. In this study, the potential of nine flavonoids to prevent GTN tolerance were examined. Changes in isometric tension in thoracic aorta of Sprague Dawley rats were studied using organ chamber ...
DescriptionMeeting Theme: Bridging Translational Gap
Chaired Posters: no. CP7
Persistent Identifierhttp://hdl.handle.net/10722/211072
ISSN
2015 SCImago Journal Rankings: 0.102

 

DC FieldValueLanguage
dc.contributor.authorZhang, L-
dc.contributor.authorLeung, SWS-
dc.contributor.authorMan, RYK-
dc.date.accessioned2015-07-06T08:31:54Z-
dc.date.available2015-07-06T08:31:54Z-
dc.date.issued2014-
dc.identifier.citationThe 18th Annual Scientific Meeting of the Institute of Cardiovascular Science and Medicine (ICSM 2014), Hong Kong, 1 November 2014. In Journal of the Hong Kong College of Cardiology, 2014, v. 22 n. 2, p. 55, abstract CP7-
dc.identifier.issn1027-7811-
dc.identifier.urihttp://hdl.handle.net/10722/211072-
dc.descriptionMeeting Theme: Bridging Translational Gap-
dc.descriptionChaired Posters: no. CP7-
dc.description.abstractGlyceryl trinitrate (GTN) is one of the most widely used anti-ischemic. However, the development of tolerance after continuous application for 24 to 72 hours limits its clinical utility. Tolerance appears to be associated with the oxidative stress induced by GTN in blood vessels. Flavonoids are important components in herbal medicine. They have antioxidative effect and potentiate vascular relaxation. In this study, the potential of nine flavonoids to prevent GTN tolerance were examined. Changes in isometric tension in thoracic aorta of Sprague Dawley rats were studied using organ chamber ...-
dc.languageeng-
dc.publisherMedcom Limited. The Journal's web site is located at http://www.hkcchk.com/journals.php#3-
dc.relation.ispartofJournal of the Hong Kong College of Cardiology-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titlePrevention of glyceryl trinitrate tolerance by flavonoids-
dc.typeConference_Paper-
dc.identifier.emailLeung, SWS: swsleung@hku.hk-
dc.identifier.emailMan, RYK: rykman@hku.hk-
dc.identifier.authorityLeung, SWS=rp00235-
dc.identifier.authorityMan, RYK=rp00236-
dc.description.naturepostprint-
dc.identifier.hkuros244692-
dc.identifier.volume22-
dc.identifier.issue2-
dc.identifier.spage55, abstract CP7-
dc.identifier.epage55, abstract CP7-
dc.publisher.placeHong Kong-

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