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  Patent History
  • Application
    US 12/4483330 2014-09-11
  • Granted
    US 20150071927 2015-03-12
  Patent Family
Supplementary

granted patent: ANTI-HER2 AND ANTI-IGF-IR BI-SPECIFIC ANTIBODIES AND USES THEREOF

TitleANTI-HER2 AND ANTI-IGF-IR BI-SPECIFIC ANTIBODIES AND USES THEREOF
Granted PatentUS 20150071927
Granted Date2015-03-12
Priority Date2013-09-11 US 12/1876564P
2014-09-11 US 12/4483330
Inventors
Issue Date2015
Citation
US Patent US 20150071927. Washington, DC: US Patent and Trademark Office (USPTO), 2015 How to Cite?
AbstractDisclosed are antibodies, or binding fragments thereof, that specifically bind to human HER2 and human IGF-IR. Also provided are nucleic acid molecules encoding the disclosed antibodies and binding fragments and vectors and host cells containing these nucleic acid molecules. The disclosure also provides methods of inhibiting cancer cell growth and metastasis in a mammal using the antibodies described herein, as well as compositions containing the antibodies, nucleic acid molecules encoding the antibodies, and host cells and vectors comprising the nucleic acid molecules. The disclosure also features the use of the polypeptides to detect the presence of HER2 and IGF-IR in a mammal, and epitopes that can be used as cancer vaccine immunogens.
Persistent Identifierhttp://hdl.handle.net/10722/210548

 

DC FieldValueLanguage
dc.date.accessioned2015-06-17T07:04:25Z-
dc.date.available2015-06-17T07:04:25Z-
dc.date.issued2015-
dc.identifier.citationUS Patent US 20150071927. Washington, DC: US Patent and Trademark Office (USPTO), 2015-
dc.identifier.urihttp://hdl.handle.net/10722/210548-
dc.description.abstractDisclosed are antibodies, or binding fragments thereof, that specifically bind to human HER2 and human IGF-IR. Also provided are nucleic acid molecules encoding the disclosed antibodies and binding fragments and vectors and host cells containing these nucleic acid molecules. The disclosure also provides methods of inhibiting cancer cell growth and metastasis in a mammal using the antibodies described herein, as well as compositions containing the antibodies, nucleic acid molecules encoding the antibodies, and host cells and vectors comprising the nucleic acid molecules. The disclosure also features the use of the polypeptides to detect the presence of HER2 and IGF-IR in a mammal, and epitopes that can be used as cancer vaccine immunogens.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License for public patent documents-
dc.titleANTI-HER2 AND ANTI-IGF-IR BI-SPECIFIC ANTIBODIES AND USES THEREOF-
dc.typePatent-
dc.identifier.authorityZHANG MEI-YUN=rp01409-
dc.description.naturepublished_or_final_version-
dc.contributor.inventorZHANG MEI-YUN-
patents.identifier.applicationUS 12/4483330-
patents.identifier.grantedUS 20150071927-
patents.description.assigneeUNIV HONG KONG [CN] -
patents.description.countryUnited States of America -
patents.date.granted2015-03-12-
patents.identifier.hkutechidMicro-2013-00471-1-
patents.date.application2014-09-11-
patents.date.priority2013-09-11 US 12/1876564P-
patents.date.priority2014-09-11 US 12/4483330-
patents.description.ccus-
patents.relation.familyCN 104418947 (A) 2015-03-18-
patents.description.kindA1-
patents.typePatent_granted-

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