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Conference Paper: Overexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma

TitleOverexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma
Authors
Issue Date2015
PublisherAmerican Association for Cancer Research. The Conference abstracts' website is located at http://www.abstractsonline.com/Plan/AdvancedSearch.aspx
Citation
The 2015 Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015. How to Cite?
AbstractThis study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ...
DescriptionSection 15: abstract no. 2252
Persistent Identifierhttp://hdl.handle.net/10722/210349

 

DC FieldValueLanguage
dc.contributor.authorMa, W-
dc.contributor.authorHo, DWH-
dc.contributor.authorNg, IOL-
dc.date.accessioned2015-06-10T01:02:09Z-
dc.date.available2015-06-10T01:02:09Z-
dc.date.issued2015-
dc.identifier.citationThe 2015 Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015.-
dc.identifier.urihttp://hdl.handle.net/10722/210349-
dc.descriptionSection 15: abstract no. 2252-
dc.description.abstractThis study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ...-
dc.languageeng-
dc.publisherAmerican Association for Cancer Research. The Conference abstracts' website is located at http://www.abstractsonline.com/Plan/AdvancedSearch.aspx-
dc.relation.ispartofAACR Annual Meeting 2015-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleOverexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma-
dc.typeConference_Paper-
dc.identifier.emailMa, W: rwma@hku.hk-
dc.identifier.emailHo, DWH: dwhho@hku.hk-
dc.identifier.emailNg, IOL: iolng@hku.hk-
dc.identifier.authorityNg, IOL=rp00335-
dc.description.naturepostprint-
dc.identifier.hkuros243521-
dc.publisher.placeUnited States-

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