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Conference Paper: Overexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma
Title | Overexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma |
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Authors | |
Issue Date | 2015 |
Publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ |
Citation | The 106th Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015. In Cancer Research, 2015, v. 75 n. 15 suppl., abstract no. 2252 How to Cite? |
Abstract | This study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ... |
Description | Section 15 - Tumor Biology: abstract no. 2252 |
Persistent Identifier | http://hdl.handle.net/10722/210349 |
ISSN | 2021 Impact Factor: 13.312 2020 SCImago Journal Rankings: 4.103 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ma, W | - |
dc.contributor.author | Ho, DWH | - |
dc.contributor.author | Ng, IOL | - |
dc.date.accessioned | 2015-06-10T01:02:09Z | - |
dc.date.available | 2015-06-10T01:02:09Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | The 106th Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015. In Cancer Research, 2015, v. 75 n. 15 suppl., abstract no. 2252 | - |
dc.identifier.issn | 0008-5472 | - |
dc.identifier.uri | http://hdl.handle.net/10722/210349 | - |
dc.description | Section 15 - Tumor Biology: abstract no. 2252 | - |
dc.description.abstract | This study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ... | - |
dc.language | eng | - |
dc.publisher | American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/ | - |
dc.relation.ispartof | Cancer Research | - |
dc.title | Overexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Ma, W: rwma@hku.hk | - |
dc.identifier.email | Ho, DWH: dwhho@hku.hk | - |
dc.identifier.email | Ng, IOL: iolng@hku.hk | - |
dc.identifier.authority | Ng, IOL=rp00335 | - |
dc.description.nature | postprint | - |
dc.identifier.doi | 10.1158/1538-7445.AM2015-2252 | - |
dc.identifier.hkuros | 243521 | - |
dc.identifier.volume | 75 | - |
dc.identifier.issue | 15 suppl., abstract no. 2252 | - |
dc.identifier.isi | WOS:000371578504355 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0008-5472 | - |