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Conference Paper: Overexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma

TitleOverexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma
Authors
Issue Date2015
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 106th Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015. In Cancer Research, 2015, v. 75 n. 15 suppl., abstract no. 2252 How to Cite?
AbstractThis study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ...
DescriptionSection 15 - Tumor Biology: abstract no. 2252
Persistent Identifierhttp://hdl.handle.net/10722/210349
ISSN
2015 Impact Factor: 8.556
2015 SCImago Journal Rankings: 5.372

 

DC FieldValueLanguage
dc.contributor.authorMa, W-
dc.contributor.authorHo, DWH-
dc.contributor.authorNg, IOL-
dc.date.accessioned2015-06-10T01:02:09Z-
dc.date.available2015-06-10T01:02:09Z-
dc.date.issued2015-
dc.identifier.citationThe 106th Annual Meeting of the American Association for Cancer Research (AACR 2015), Philadelphia, PA., 18-22 April 2015. In Cancer Research, 2015, v. 75 n. 15 suppl., abstract no. 2252-
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/210349-
dc.descriptionSection 15 - Tumor Biology: abstract no. 2252-
dc.description.abstractThis study aims at revealing the roles of APOBEC3B (A3B) in human hepatocellular carcinoma (HCC). HCC is a leading cancer worldwide and specifically prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. Recent evidence has implicated A3B, a DNA deaminase, as a source of mutations in breast, cervical and bladder cancers. For example, A3B was found upregulated and active in the majority of breast cancer cell lines, and its upregulation in tumors correlated with increased C-to-T transition and overall base substitution ...-
dc.languageeng-
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/-
dc.relation.ispartofCancer Research-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.titleOverexpression of APOBEC3B enhances invasiveness of hepatocellular carcinoma-
dc.typeConference_Paper-
dc.identifier.emailMa, W: rwma@hku.hk-
dc.identifier.emailHo, DWH: dwhho@hku.hk-
dc.identifier.emailNg, IOL: iolng@hku.hk-
dc.identifier.authorityNg, IOL=rp00335-
dc.description.naturepostprint-
dc.identifier.doi10.1158/1538-7445.AM2015-2252-
dc.identifier.hkuros243521-
dc.identifier.volume75-
dc.identifier.issue15 suppl., abstract no. 2252-
dc.publisher.placeUnited States-

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