File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1007/s00330-014-3265-z
- Scopus: eid_2-s2.0-84905912917
- WOS: WOS:000340519200006
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Effects of gender, age, and body mass index on fat contents and apparent diffusion coefficients in healthy parotid glands: An MRI evaluation
Title | Effects of gender, age, and body mass index on fat contents and apparent diffusion coefficients in healthy parotid glands: An MRI evaluation |
---|---|
Authors | |
Keywords | Fat saturation Parotid ADC measurement IDEAL fat-water separation PROPELLER Parotid fat content |
Issue Date | 2014 |
Citation | European Radiology, 2014, v. 24, n. 9, p. 2069-2076 How to Cite? |
Abstract | Objectives: To establish standard apparent diffusion coefficient (ADC) and the fat content as a function of age, gender and body mass index (BMI) in healthy parotid glands, and to address the influences of fat suppression on ADC measurements. Methods: A total of 100 healthy adults (gender and age evenly distributed) were prospectively recruited, with parotid fat content measured from gradient-echo images with fat-water separated using iterative decomposition with echo asymmetry and least squares (IDEAL). The ADCs were estimated using both fat-saturated and non-fat-saturated diffusion-weighted imaging via a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) technique. Results: Parotid fat content was larger in men than in women by about 10 percentage points (P<0.005), and positively associated with BMI and age for both genders (mostly with P<0.001). ADCs estimated with non-fat-saturated PROPELLER were significantly lower in men than in women (P<0.005), but showed no gender difference if measured using fat-saturated PROPELLER (P=0.840). The negative association between parotid ADC and age/BMI/fat (P<0.001) showed greater regression slopes in non-fat-saturated PROPELLER than in fat-saturated data. Conclusions: Parotid fat content in healthy adults correlates positively with both age and BMI; the correlation with age is gender-dependent. Parotid ADC measurements are strongly influenced by fat saturation. Key Points: • Parotid fat content in healthy adults correlates positively with age and BMI. • The rate of aging-related increase in fat contents is gender-dependent. • Parotid ADC measurements are strongly influenced by fat saturation. © 2014 European Society of Radiology. |
Persistent Identifier | http://hdl.handle.net/10722/210134 |
ISSN | 2021 Impact Factor: 7.034 2020 SCImago Journal Rankings: 1.606 |
ISI Accession Number ID |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, Hing Chiu | - |
dc.contributor.author | Juan, Chun Jung | - |
dc.contributor.author | Chiu, Hui Chu | - |
dc.contributor.author | Cheng, Cheng Chieh | - |
dc.contributor.author | Chiu, Su Chin | - |
dc.contributor.author | Liu, Yi Jui | - |
dc.contributor.author | Chung, Hsiao Wen | - |
dc.contributor.author | Hsu, Hsian He | - |
dc.date.accessioned | 2015-05-22T06:06:44Z | - |
dc.date.available | 2015-05-22T06:06:44Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | European Radiology, 2014, v. 24, n. 9, p. 2069-2076 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.uri | http://hdl.handle.net/10722/210134 | - |
dc.description.abstract | Objectives: To establish standard apparent diffusion coefficient (ADC) and the fat content as a function of age, gender and body mass index (BMI) in healthy parotid glands, and to address the influences of fat suppression on ADC measurements. Methods: A total of 100 healthy adults (gender and age evenly distributed) were prospectively recruited, with parotid fat content measured from gradient-echo images with fat-water separated using iterative decomposition with echo asymmetry and least squares (IDEAL). The ADCs were estimated using both fat-saturated and non-fat-saturated diffusion-weighted imaging via a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) technique. Results: Parotid fat content was larger in men than in women by about 10 percentage points (P<0.005), and positively associated with BMI and age for both genders (mostly with P<0.001). ADCs estimated with non-fat-saturated PROPELLER were significantly lower in men than in women (P<0.005), but showed no gender difference if measured using fat-saturated PROPELLER (P=0.840). The negative association between parotid ADC and age/BMI/fat (P<0.001) showed greater regression slopes in non-fat-saturated PROPELLER than in fat-saturated data. Conclusions: Parotid fat content in healthy adults correlates positively with both age and BMI; the correlation with age is gender-dependent. Parotid ADC measurements are strongly influenced by fat saturation. Key Points: • Parotid fat content in healthy adults correlates positively with age and BMI. • The rate of aging-related increase in fat contents is gender-dependent. • Parotid ADC measurements are strongly influenced by fat saturation. © 2014 European Society of Radiology. | - |
dc.language | eng | - |
dc.relation.ispartof | European Radiology | - |
dc.subject | Fat saturation | - |
dc.subject | Parotid ADC measurement | - |
dc.subject | IDEAL fat-water separation | - |
dc.subject | PROPELLER | - |
dc.subject | Parotid fat content | - |
dc.title | Effects of gender, age, and body mass index on fat contents and apparent diffusion coefficients in healthy parotid glands: An MRI evaluation | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1007/s00330-014-3265-z | - |
dc.identifier.scopus | eid_2-s2.0-84905912917 | - |
dc.identifier.volume | 24 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 2069 | - |
dc.identifier.epage | 2076 | - |
dc.identifier.eissn | 1432-1084 | - |
dc.identifier.isi | WOS:000340519200006 | - |
dc.identifier.issnl | 0938-7994 | - |