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Article: Optic neuritis in Hong Kong: a 1-year follow-up study

TitleOptic neuritis in Hong Kong: a 1-year follow-up study
Authors
Issue Date2015
Citation
International Ophthalmology, 2015, v. 35 n. 3, p. 303-310 How to Cite?
AbstractTo investigate the etiology and prevalence of optic neuritis in a Chinese population. This was a single centre prospective cohort study. Consecutive patients with either a first or recurrent attack of optic neuritis from November 2010 to December 2011 were recruited from a district hospital in Hong Kong Special Administrative Region, China. All patients underwent serology testing for NMO (neuromyelitis optica) IgG; oligoclonal bands from lumbar puncture; computer tomography and contrast magnetic resonance imaging (MRI) of the brain and orbit as well as visual field; and optical coherence tomography testing. Patients were followed up for 1 year after the initial attack. 30 optic neuritis subjects were recruited. 73.3 % (22/30) remain as clinical isolated syndrome (CIS) after 1-year follow-up. 10 % (3/30) patients developed multiple sclerosis. 10 % (3/30) were diagnosed with NMO and 6.7 % (2/30) with NMO-spectrum disorder. The majority of acute unilateral optic neuritis in Chinese was CIS in origin although a fraction does progress to develop MS or NMO-related disorders. Clinicians should be aware of the associations and offer appropriate systemic workups.
Persistent Identifierhttp://hdl.handle.net/10722/208493
ISSN
2015 SCImago Journal Rankings: 0.526

 

DC FieldValueLanguage
dc.contributor.authorLau, PPen_US
dc.contributor.authorYau, GSen_US
dc.contributor.authorLee, WYJen_US
dc.contributor.authorWong, WWen_US
dc.contributor.authorTam, VTen_US
dc.contributor.authorChan, EYen_US
dc.contributor.authorTse, DMen_US
dc.contributor.authorYuen, CYen_US
dc.date.accessioned2015-03-11T07:06:24Z-
dc.date.available2015-03-11T07:06:24Z-
dc.date.issued2015en_US
dc.identifier.citationInternational Ophthalmology, 2015, v. 35 n. 3, p. 303-310en_US
dc.identifier.issn1573-2630en_US
dc.identifier.urihttp://hdl.handle.net/10722/208493-
dc.description.abstractTo investigate the etiology and prevalence of optic neuritis in a Chinese population. This was a single centre prospective cohort study. Consecutive patients with either a first or recurrent attack of optic neuritis from November 2010 to December 2011 were recruited from a district hospital in Hong Kong Special Administrative Region, China. All patients underwent serology testing for NMO (neuromyelitis optica) IgG; oligoclonal bands from lumbar puncture; computer tomography and contrast magnetic resonance imaging (MRI) of the brain and orbit as well as visual field; and optical coherence tomography testing. Patients were followed up for 1 year after the initial attack. 30 optic neuritis subjects were recruited. 73.3 % (22/30) remain as clinical isolated syndrome (CIS) after 1-year follow-up. 10 % (3/30) patients developed multiple sclerosis. 10 % (3/30) were diagnosed with NMO and 6.7 % (2/30) with NMO-spectrum disorder. The majority of acute unilateral optic neuritis in Chinese was CIS in origin although a fraction does progress to develop MS or NMO-related disorders. Clinicians should be aware of the associations and offer appropriate systemic workups.en_US
dc.languageengen_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.titleOptic neuritis in Hong Kong: a 1-year follow-up studyen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.1007/s10792-014-9945-5en_US
dc.identifier.pmid24728535-
dc.identifier.scopuseid_2-s2.0-84939896815-
dc.identifier.hkuros244328-

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