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Article: Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese

TitlePredictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese
Authors
Issue Date2014
Citation
Clinical Ophthalmology, 2014, v. 8, p. 1787-1791 How to Cite?
AbstractPURPOSE: To determine the predictors of success for adjuvant selective laser trabeculoplasty (SLT) in Chinese primary open angle glaucoma (POAG) patients. METHODS: This prospective study recruited Chinese subjects with unilateral or bilateral POAG currently taking medication to reduce intraocular pressure (IOP). All subjects received a single session of 360 degrees SLT treatment and continued their medications for 1 month. SLT success was defined as IOP reduction >/=20% at 1 month. The following covariates were analyzed in both groups via univariate and multivariate analyses: age, sex, lens status, initial IOPs, post-SLT IOPs, number and type of medications, SLT shots and energy, and pre-SLT investigations. RESULTS: In 51 eyes of 33 POAG subjects, the success rate of SLT was 47.1%. Certain groups of patients were associated with greater success using univariate analysis. These groups included the following: older age (coefficient =0.1; OR: 1.1; P=0.0003), a higher pre-SLT IOP (coefficient =0.3; OR: 1.3; P=0.0005), using four types of antiglaucoma medication (coefficient =2.1; OR: 8.4; P=0.005), a greater degree of spherical equivalent (coefficient =2.1; OR: 8.4; P=0.005), and the use of a topical carbonic anhydrase inhibitor (coefficient =1.7; OR: 6.0; P=0.003). None of the covariates were significant using multivariate analysis. CONCLUSION: Older age, a higher pretreatment IOP, using multiple antiglaucoma medications especially topical carbonic anhydrase inhibitor, and higher refractive errors were associated with greater SLT success.
Persistent Identifierhttp://hdl.handle.net/10722/208487
ISSN
2015 SCImago Journal Rankings: 0.787
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorLee, WYJen_US
dc.contributor.authorLiu, CCen_US
dc.contributor.authorChan, JCHen_US
dc.contributor.authorWong, RLen_US
dc.contributor.authorWong, IYen_US
dc.contributor.authorLai, JSen_US
dc.date.accessioned2015-03-11T07:06:21Z-
dc.date.available2015-03-11T07:06:21Z-
dc.date.issued2014en_US
dc.identifier.citationClinical Ophthalmology, 2014, v. 8, p. 1787-1791en_US
dc.identifier.issn1177-5467en_US
dc.identifier.urihttp://hdl.handle.net/10722/208487-
dc.description.abstractPURPOSE: To determine the predictors of success for adjuvant selective laser trabeculoplasty (SLT) in Chinese primary open angle glaucoma (POAG) patients. METHODS: This prospective study recruited Chinese subjects with unilateral or bilateral POAG currently taking medication to reduce intraocular pressure (IOP). All subjects received a single session of 360 degrees SLT treatment and continued their medications for 1 month. SLT success was defined as IOP reduction >/=20% at 1 month. The following covariates were analyzed in both groups via univariate and multivariate analyses: age, sex, lens status, initial IOPs, post-SLT IOPs, number and type of medications, SLT shots and energy, and pre-SLT investigations. RESULTS: In 51 eyes of 33 POAG subjects, the success rate of SLT was 47.1%. Certain groups of patients were associated with greater success using univariate analysis. These groups included the following: older age (coefficient =0.1; OR: 1.1; P=0.0003), a higher pre-SLT IOP (coefficient =0.3; OR: 1.3; P=0.0005), using four types of antiglaucoma medication (coefficient =2.1; OR: 8.4; P=0.005), a greater degree of spherical equivalent (coefficient =2.1; OR: 8.4; P=0.005), and the use of a topical carbonic anhydrase inhibitor (coefficient =1.7; OR: 6.0; P=0.003). None of the covariates were significant using multivariate analysis. CONCLUSION: Older age, a higher pretreatment IOP, using multiple antiglaucoma medications especially topical carbonic anhydrase inhibitor, and higher refractive errors were associated with greater SLT success.en_US
dc.languageengen_US
dc.relation.ispartofClinical Ophthalmologyen_US
dc.titlePredictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chineseen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.2147/OPTH.S69166en_US
dc.identifier.pmid25228796-
dc.identifier.pmcid4164283-
dc.identifier.scopuseid_2-s2.0-84907697049-
dc.identifier.volume8en_US
dc.identifier.spage1787en_US
dc.identifier.epage1791en_US

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