File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Predictors of success in selective laser trabeculoplasty for chinese open-angle glaucoma

TitlePredictors of success in selective laser trabeculoplasty for chinese open-angle glaucoma
Authors
Issue Date2014
Citation
Journal of Glaucoma, 2014, v. 23 n. 5, p. 321-325 How to Cite?
AbstractAIM: To investigate the determinants of success of selective laser trabeculoplasty (SLT) in Chinese open-angle glaucoma patients. METHODS: This prospective cohort study sequentially recruited Chinese subjects with unilateral or bilateral primary open-angle glaucoma (POAG) or normal tension glaucoma (NTG). All subjects received a single session of 360-degree SLT treatment. Success was defined as IOP reduction >/=20%. The following were analyzed in univariate and multivariate regression analyses for association with SLT success: type of glaucoma, age, sex, lens status, presenting IOP, pre-SLT IOP, day 1 IOP, 1-week IOP, number and type of anti-glaucoma medications, number of SLT shots and energy, retinal nerve fiber layer (RNFL) thickness, Visual Field Index, endothelial cell count, central corneal thickness, Snellen visual acuity, and spherical equivalent. RESULTS: In 111 eyes of 65 subjects, there were 51 POAG eyes and 60 NTG eyes. The overall success was 53.15% with a mean IOP reduction of 19.81+/-15.93%. In univariate analysis, a thinner RNFL [coefficient=-0.027; odds ratio (OR)=0.95; P=0.017] was associated with success. In multivariate analysis, a lower day 1 IOP (coefficient=-0.29; OR=0.75; P=0.049) and using topical carbonic anhydrase inhibitors (CAI) (coefficient=2.92; OR=18.63; P=0.0020) were associated with success. In both univariate and multivariate analyses, a higher pre-SLT IOP significantly predicted success (coefficient=0.20/0.46; OR=1.23/1.58; P=0.0017/0.0011) and using 3 anti-glaucoma medications (coefficient=-1.08/-3.74; OR=0.3/0.024; P=0.037/P=0.0081) was associated with SLT failure. CONCLUSION: The positive predictors of SLT success included: higher pre-SLT IOP, use of topical CAI, thinner RNFL, and lower day 1 IOP. Using 3 anti-glaucoma medications was associated with failure.
Persistent Identifierhttp://hdl.handle.net/10722/208486
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLee, WYJen_US
dc.contributor.authorLiu, CCen_US
dc.contributor.authorChan, JCen_US
dc.contributor.authorLai, JSen_US
dc.date.accessioned2015-03-11T07:06:21Z-
dc.date.available2015-03-11T07:06:21Z-
dc.date.issued2014en_US
dc.identifier.citationJournal of Glaucoma, 2014, v. 23 n. 5, p. 321-325en_US
dc.identifier.issn1536-481Xen_US
dc.identifier.urihttp://hdl.handle.net/10722/208486-
dc.description.abstractAIM: To investigate the determinants of success of selective laser trabeculoplasty (SLT) in Chinese open-angle glaucoma patients. METHODS: This prospective cohort study sequentially recruited Chinese subjects with unilateral or bilateral primary open-angle glaucoma (POAG) or normal tension glaucoma (NTG). All subjects received a single session of 360-degree SLT treatment. Success was defined as IOP reduction >/=20%. The following were analyzed in univariate and multivariate regression analyses for association with SLT success: type of glaucoma, age, sex, lens status, presenting IOP, pre-SLT IOP, day 1 IOP, 1-week IOP, number and type of anti-glaucoma medications, number of SLT shots and energy, retinal nerve fiber layer (RNFL) thickness, Visual Field Index, endothelial cell count, central corneal thickness, Snellen visual acuity, and spherical equivalent. RESULTS: In 111 eyes of 65 subjects, there were 51 POAG eyes and 60 NTG eyes. The overall success was 53.15% with a mean IOP reduction of 19.81+/-15.93%. In univariate analysis, a thinner RNFL [coefficient=-0.027; odds ratio (OR)=0.95; P=0.017] was associated with success. In multivariate analysis, a lower day 1 IOP (coefficient=-0.29; OR=0.75; P=0.049) and using topical carbonic anhydrase inhibitors (CAI) (coefficient=2.92; OR=18.63; P=0.0020) were associated with success. In both univariate and multivariate analyses, a higher pre-SLT IOP significantly predicted success (coefficient=0.20/0.46; OR=1.23/1.58; P=0.0017/0.0011) and using 3 anti-glaucoma medications (coefficient=-1.08/-3.74; OR=0.3/0.024; P=0.037/P=0.0081) was associated with SLT failure. CONCLUSION: The positive predictors of SLT success included: higher pre-SLT IOP, use of topical CAI, thinner RNFL, and lower day 1 IOP. Using 3 anti-glaucoma medications was associated with failure.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Glaucomaen_US
dc.titlePredictors of success in selective laser trabeculoplasty for chinese open-angle glaucomaen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.1097/IJG.0000000000000049en_US
dc.identifier.pmid24886702-
dc.identifier.scopuseid_2-s2.0-84902142875-
dc.identifier.hkuros264613-
dc.identifier.volume23en_US
dc.identifier.issue5en_US
dc.identifier.spage321en_US
dc.identifier.epage325en_US
dc.identifier.isiWOS:000337299100010-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats