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Article: Predictors of success in selective laser trabeculoplasty for normal tension glaucoma

TitlePredictors of success in selective laser trabeculoplasty for normal tension glaucoma
Authors
Issue Date2014
Citation
Medicine (Baltimore), 2014, v. 93 n. 28, p. e236 How to Cite?
AbstractTo determine the predictors of success for selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG).This prospective cohort study recruited subjects with unilateral or bilateral NTG on medication. All subjects received a single session of 360 degrees SLT treatment. SLT success was defined as IOP reduction >/=20% at 1-month. The following covariates were analyzed via univariate and multivariate analyses: age; sex; lens status; presenting, pre-SLT, and post-SLT IOP's; number and type of medications; SLT shots and energy; and pre-SLT investigations.In 60 eyes of 32 subjects with NTG, there were 30 right eyes and 28 left eyes. The success rate of SLT was 61.7%. Using 3 types of anti-glaucoma medications (coefficient = -2.2, OR = 0.1, P = 0.02) and a thicker retinal nerve fiber layer thickness (coefficient = -0.04, OR = 0.96, P = 0.04) were associated with failure (univariate analysis). In multivariate analysis, a higher pre-SLT IOP (coefficient = 1.1, OR = 3.1, P = 0.05) and a lower 1-week IOP (coefficient = -0.8, OR = 0.5, P = 0.04) were associated with success.SLT was successful in over 60% of treated NTG patients. A higher pre-SLT IOP and a greater IOP reduction at 1-week post-SLT were predictors of a successful outcome.
Persistent Identifierhttp://hdl.handle.net/10722/208485
ISSN
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLee, WYJen_US
dc.contributor.authorLiu, CCen_US
dc.contributor.authorChan, JCen_US
dc.contributor.authorLai, JSen_US
dc.date.accessioned2015-03-11T07:06:21Z-
dc.date.available2015-03-11T07:06:21Z-
dc.date.issued2014en_US
dc.identifier.citationMedicine (Baltimore), 2014, v. 93 n. 28, p. e236en_US
dc.identifier.issn1536-5964en_US
dc.identifier.urihttp://hdl.handle.net/10722/208485-
dc.description.abstractTo determine the predictors of success for selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG).This prospective cohort study recruited subjects with unilateral or bilateral NTG on medication. All subjects received a single session of 360 degrees SLT treatment. SLT success was defined as IOP reduction >/=20% at 1-month. The following covariates were analyzed via univariate and multivariate analyses: age; sex; lens status; presenting, pre-SLT, and post-SLT IOP's; number and type of medications; SLT shots and energy; and pre-SLT investigations.In 60 eyes of 32 subjects with NTG, there were 30 right eyes and 28 left eyes. The success rate of SLT was 61.7%. Using 3 types of anti-glaucoma medications (coefficient = -2.2, OR = 0.1, P = 0.02) and a thicker retinal nerve fiber layer thickness (coefficient = -0.04, OR = 0.96, P = 0.04) were associated with failure (univariate analysis). In multivariate analysis, a higher pre-SLT IOP (coefficient = 1.1, OR = 3.1, P = 0.05) and a lower 1-week IOP (coefficient = -0.8, OR = 0.5, P = 0.04) were associated with success.SLT was successful in over 60% of treated NTG patients. A higher pre-SLT IOP and a greater IOP reduction at 1-week post-SLT were predictors of a successful outcome.en_US
dc.languageengen_US
dc.relation.ispartofMedicine (Baltimore)en_US
dc.titlePredictors of success in selective laser trabeculoplasty for normal tension glaucomaen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.1097/MD.0000000000000236en_US
dc.identifier.pmid25526445-
dc.identifier.pmcidPMC4603124-
dc.identifier.scopuseid_2-s2.0-84920149194-
dc.identifier.hkuros264615-
dc.identifier.volume93en_US
dc.identifier.issue28en_US
dc.identifier.spagee236en_US
dc.identifier.epagee236en_US
dc.identifier.isiWOS:000346762200016-

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