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Article: Incidence and risk factors for retinopathy of prematurity in extreme low birth weight Chinese infants

TitleIncidence and risk factors for retinopathy of prematurity in extreme low birth weight Chinese infants
Authors
Issue Date2015
Citation
International Ophthalmology, 2015, v. 35 n. 3, p. 365-373 How to Cite?
AbstractThe objective of this study is to determine the incidence and risk factors of retinopathy of prematurity (ROP) in extremely low birth weight (ELBW) Chinese infants. A retrospective medical record review of all ELBW (
Persistent Identifierhttp://hdl.handle.net/10722/208475
ISSN
2015 SCImago Journal Rankings: 0.526

 

DC FieldValueLanguage
dc.contributor.authorYau, GSen_US
dc.contributor.authorLee, WYJen_US
dc.contributor.authorTam, VTen_US
dc.contributor.authorLiu, CCen_US
dc.contributor.authorChu, BCen_US
dc.contributor.authorYuen, CYen_US
dc.date.accessioned2015-03-11T07:06:15Z-
dc.date.available2015-03-11T07:06:15Z-
dc.date.issued2015en_US
dc.identifier.citationInternational Ophthalmology, 2015, v. 35 n. 3, p. 365-373en_US
dc.identifier.issn1573-2630en_US
dc.identifier.urihttp://hdl.handle.net/10722/208475-
dc.description.abstractThe objective of this study is to determine the incidence and risk factors of retinopathy of prematurity (ROP) in extremely low birth weight (ELBW) Chinese infants. A retrospective medical record review of all ELBW (</=1,000 g) neonates screened for ROP from 2007 to 2012 was performed in Hong Kong. ROP screening was conducted at 2 neonatal intensive care units by 3 pediatric ophthalmologists using the Royal College of Ophthalmologists ROP guideline and the International Classification of ROP. Maternal and neonatal covariates were analyzed using univariate and multivariate regression analyses for both ROP and Type 1 ROP. In 131 ELBW Chinese infants, the mean gestational age (GA) and birth weight (BW) were 27.3 +/- 3.3 weeks and 806.9 +/- 133.7 g, respectively. The incidence of ROP and Type 1 ROP was 53.4 and 14.5 %, respectively. For ROP, a lighter BW, smaller GA, vaginal delivery, postnatal hypotension, inotrope use, bronchopulmonary dysplasia, surfactant use, invasive mechanical ventilation, and supplementary oxygen were independent risk factors for ROP, while PET was protective (P </= 0.02). On multivariate analysis, a smaller GA was a risk factor, while PET and congenital heart disease were protective for ROP development (P </= 0.01). For Type 1 ROP, a lighter BW, smaller GA, surfactant use, and invasive mechanical ventilation were independent risk factors for ROP, while PET was protective (P </= 0.02). There were no significant covariates on multivariate analysis for Type 1 ROP. In ELBW, preterm Chinese infants, a smaller GA was a risk factor for ROP, while PET and congenital heart disease were protective for ROP development in multivariate analysis.en_US
dc.languageengen_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.titleIncidence and risk factors for retinopathy of prematurity in extreme low birth weight Chinese infantsen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.1007/s10792-014-9956-2en_US
dc.identifier.pmid24898774-
dc.identifier.scopuseid_2-s2.0-84939885252-
dc.identifier.hkuros244327-

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