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Article: Neuromyelitis optica spectrum disorder in a chinese woman with ocular myasthenia gravis: First reported case in the chinese population

TitleNeuromyelitis optica spectrum disorder in a chinese woman with ocular myasthenia gravis: First reported case in the chinese population
Authors
KeywordsNeuromyelitis optica
Nmo-Igg seropositivity
Ocular myasthenia
Issue Date2014
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01658107.asp
Citation
Neuro-Ophthalmology, 2014, v. 38 n. 3, p. 140-144 How to Cite?
AbstractCoexisting myasthenia gravis and neuromyelitis optica spectrum disorder was reported as a rare association, with only 26 reported cases in the literature. The authors report the case of a middle-aged Chinese woman with bilateral recurrent optic neuritis and seropositive ocular myasthenia gravis who was subsequently diagnosed with neuromyelitis optica spectrum. She was tested seropositive for the neuromyelitis optica immunoglobulin G (NMO-IgG) and had elevated antinuclear antibody titres, but workup for other autoimmune disorders were negative. She was subsequently prescribed with azathioprine and pyridostigmine, and showed good control of both autoimmune disorders. To the best of the authors' knowledge, this is the first reported case in the literature of a Chinese patient with seropositivity for both anti-acetylcholine receptor and NMO-IgG without a thymic disorder. Testing of NMO-IgG may be considered in patients with optic neuritis with underlying autoimmune disorders even in the absence of transverse myelitis for the detection of associated neuromyelitis optica spectrum disorders. © 2014 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.
Persistent Identifierhttp://hdl.handle.net/10722/208472
ISSN
2012 Impact Factor: 0.184
2015 SCImago Journal Rankings: 0.147

 

DC FieldValueLanguage
dc.contributor.authorYau, GSKen_US
dc.contributor.authorLee, WYJen_US
dc.contributor.authorChan, TTKen_US
dc.contributor.authorYuen, CYFen_US
dc.date.accessioned2015-03-11T07:06:14Z-
dc.date.available2015-03-11T07:06:14Z-
dc.date.issued2014en_US
dc.identifier.citationNeuro-Ophthalmology, 2014, v. 38 n. 3, p. 140-144en_US
dc.identifier.issn0165-8107en_US
dc.identifier.urihttp://hdl.handle.net/10722/208472-
dc.description.abstractCoexisting myasthenia gravis and neuromyelitis optica spectrum disorder was reported as a rare association, with only 26 reported cases in the literature. The authors report the case of a middle-aged Chinese woman with bilateral recurrent optic neuritis and seropositive ocular myasthenia gravis who was subsequently diagnosed with neuromyelitis optica spectrum. She was tested seropositive for the neuromyelitis optica immunoglobulin G (NMO-IgG) and had elevated antinuclear antibody titres, but workup for other autoimmune disorders were negative. She was subsequently prescribed with azathioprine and pyridostigmine, and showed good control of both autoimmune disorders. To the best of the authors' knowledge, this is the first reported case in the literature of a Chinese patient with seropositivity for both anti-acetylcholine receptor and NMO-IgG without a thymic disorder. Testing of NMO-IgG may be considered in patients with optic neuritis with underlying autoimmune disorders even in the absence of transverse myelitis for the detection of associated neuromyelitis optica spectrum disorders. © 2014 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/01658107.aspen_US
dc.relation.ispartofNeuro-Ophthalmologyen_US
dc.subjectNeuromyelitis opticaen_US
dc.subjectNmo-Igg seropositivityen_US
dc.subjectOcular myastheniaen_US
dc.titleNeuromyelitis optica spectrum disorder in a chinese woman with ocular myasthenia gravis: First reported case in the chinese populationen_US
dc.typeArticleen_US
dc.identifier.emailLee, WYJ: jackylee@hku.hken_US
dc.identifier.authorityLee, WYJ=rp01498en_US
dc.identifier.doi10.3109/01658107.2013.879903en_US
dc.identifier.scopuseid_2-s2.0-84900542185-
dc.identifier.volume38en_US
dc.identifier.issue3en_US
dc.identifier.spage140en_US
dc.identifier.epage144en_US

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