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Article: Age-related and diurnal changes in met5-enk-arg6-phe7 and met5-enkephalin contents of pituitary and rat brain structures

TitleAge-related and diurnal changes in met5-enk-arg6-phe7 and met5-enkephalin contents of pituitary and rat brain structures
Authors
Issue Date1984
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie
Citation
Life Sciences, 1984, v. 35 n. 9, p. 1005-1014 How to Cite?
AbstractThe β-endorphin, met5-enkephalin-arg6-phe7 (MEAP) and met5-enkephalin (ME) changes related to age and diurnal rhythms were studied in various regions of rat brain and in the pituitary by specific radioimmunoassays. The contents of MEAP, met5-enkephalin and β-endorphin were higher in the pituitary of old rats (18 months old) than that of young rats (23 days old) while the content of these opioid peptides was higher in the hyphotalamus of young rats than in that of old rats. β-endorphin was also higher in the striatum of 23 days old rats, but no age-associated changes were observed in the hippocampus, brain stem or cortex. In the diurnal rhythm study, it was found that in the hypothalamus and striatum of the adult rat (2-3 months old), both MEAP and ME contents were higher at mid-dark than at mid-light and that in the intermediate posterior lobe of the pituitary, the ME content was also higher at mid-dark. © 1984.
Persistent Identifierhttp://hdl.handle.net/10722/208161
ISSN
2015 Impact Factor: 2.685
2015 SCImago Journal Rankings: 1.056
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTang, F-
dc.contributor.authorTang, J-
dc.contributor.authorChou, J-
dc.date.accessioned2015-02-16T06:55:07Z-
dc.date.available2015-02-16T06:55:07Z-
dc.date.issued1984-
dc.identifier.citationLife Sciences, 1984, v. 35 n. 9, p. 1005-1014-
dc.identifier.issn0024-3205-
dc.identifier.urihttp://hdl.handle.net/10722/208161-
dc.description.abstractThe β-endorphin, met5-enkephalin-arg6-phe7 (MEAP) and met5-enkephalin (ME) changes related to age and diurnal rhythms were studied in various regions of rat brain and in the pituitary by specific radioimmunoassays. The contents of MEAP, met5-enkephalin and β-endorphin were higher in the pituitary of old rats (18 months old) than that of young rats (23 days old) while the content of these opioid peptides was higher in the hyphotalamus of young rats than in that of old rats. β-endorphin was also higher in the striatum of 23 days old rats, but no age-associated changes were observed in the hippocampus, brain stem or cortex. In the diurnal rhythm study, it was found that in the hypothalamus and striatum of the adult rat (2-3 months old), both MEAP and ME contents were higher at mid-dark than at mid-light and that in the intermediate posterior lobe of the pituitary, the ME content was also higher at mid-dark. © 1984.-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/lifescie-
dc.relation.ispartofLife Sciences-
dc.titleAge-related and diurnal changes in met5-enk-arg6-phe7 and met5-enkephalin contents of pituitary and rat brain structuresen_US
dc.typeArticle-
dc.identifier.emailTang, F: ftang@hku.hk-
dc.identifier.doi10.1016/0024-3205(84)90667-2-
dc.identifier.pmid6088930-
dc.identifier.scopuseid_2-s2.0-0021275331-
dc.identifier.hkuros700002009-
dc.identifier.volume35-
dc.identifier.issue9-
dc.identifier.spage1005-
dc.identifier.epage1014-
dc.identifier.isiWOS:A1984TD64800011-
dc.publisher.placeUnited States-

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