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Article: Randomized control trial of using tongue acupuncture in autism spectrum disorder

TitleRandomized control trial of using tongue acupuncture in autism spectrum disorder
Authors
Issue Date2014
Citation
Journal of Traditional Chinese Medical Sciences, 2014, v. 1, p. 62-72 How to Cite?
AbstractObjective The therapeutic approach of traditional chinese Medicine (TCM) in autism spectrum disorder (ASD) is a functional one. To study the efficacy, safety and functional brain change from the use of tongue acupuncture (TAC) on ASD children. Methods 21 autistic boys (3–16 years old) were randomly assigned to TAC group (TAC: n = 12; receiving daily TAC for 8 weeks) or control (C: n = 9; no acupuncture). Primary outcome measures included Autism Treatment Evaluation Checklist (ATEC), Reynell Language Developmental Scale, Symbolic Play Test (SPT), Functional Independence Measure for Children (WeeFIM), Clinical Global Impression (CGI) Scale and Cerebral FDG Metabolism by PET. Results There were significant improvement in speech domain of ATEC (p = 0.030), Self-care domain of WeeFIM (p = 0.021), cognition domain of WeeFIM (p = 0.001) and Total score domain of WeeFIM (p = 0.001) in TAC group compared to the C group. There were significant difference in positive clinical response between C and TAC group in language (p = 0.0211), functional (p = 0.0011), parental Impression criteria (p = 0.0003) and overall cerebral glucose metabolism (p = 0.0451) using ROC criteria. No significant association of PET Glucose Metabolism with Clinical response was found. None of the children developed any side-effects. Conclusion A short course of TAC can improve specific functions in children with autism spectrum disorder, especially speech and cognition function. No statistical significant association of PET Glucose Metabolism with Clinical response. Larger scale with more sample size trial should be done for further investigation.
Persistent Identifierhttp://hdl.handle.net/10722/207719

 

DC FieldValueLanguage
dc.contributor.authorWong, VCNen_US
dc.contributor.authorSun, JGen_US
dc.contributor.authorYeung, DWCen_US
dc.date.accessioned2015-01-19T09:21:20Z-
dc.date.available2015-01-19T09:21:20Z-
dc.date.issued2014en_US
dc.identifier.citationJournal of Traditional Chinese Medical Sciences, 2014, v. 1, p. 62-72en_US
dc.identifier.urihttp://hdl.handle.net/10722/207719-
dc.description.abstractObjective The therapeutic approach of traditional chinese Medicine (TCM) in autism spectrum disorder (ASD) is a functional one. To study the efficacy, safety and functional brain change from the use of tongue acupuncture (TAC) on ASD children. Methods 21 autistic boys (3–16 years old) were randomly assigned to TAC group (TAC: n = 12; receiving daily TAC for 8 weeks) or control (C: n = 9; no acupuncture). Primary outcome measures included Autism Treatment Evaluation Checklist (ATEC), Reynell Language Developmental Scale, Symbolic Play Test (SPT), Functional Independence Measure for Children (WeeFIM), Clinical Global Impression (CGI) Scale and Cerebral FDG Metabolism by PET. Results There were significant improvement in speech domain of ATEC (p = 0.030), Self-care domain of WeeFIM (p = 0.021), cognition domain of WeeFIM (p = 0.001) and Total score domain of WeeFIM (p = 0.001) in TAC group compared to the C group. There were significant difference in positive clinical response between C and TAC group in language (p = 0.0211), functional (p = 0.0011), parental Impression criteria (p = 0.0003) and overall cerebral glucose metabolism (p = 0.0451) using ROC criteria. No significant association of PET Glucose Metabolism with Clinical response was found. None of the children developed any side-effects. Conclusion A short course of TAC can improve specific functions in children with autism spectrum disorder, especially speech and cognition function. No statistical significant association of PET Glucose Metabolism with Clinical response. Larger scale with more sample size trial should be done for further investigation.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Traditional Chinese Medical Sciencesen_US
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleRandomized control trial of using tongue acupuncture in autism spectrum disorderen_US
dc.typeArticleen_US
dc.identifier.emailWong, VCN: vcnwong@hku.hken_US
dc.identifier.emailYeung, DWC: dyeung@graduate.hku.hken_US
dc.identifier.authorityWong, VCN=rp00334en_US
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1016/j.jtcms.2014.11.005-
dc.identifier.hkuros242244en_US
dc.identifier.volume1en_US
dc.identifier.spage62en_US
dc.identifier.epage72en_US

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